Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes

Trans splicing of nuclear pre-mRNAs

1990 • 383 citations

Double targeted gene replacement for creating null mutants.

1991 • 323 citations

Use of the green fluorescent protein as a marker in transfected Leishmania

1996 • 255 citations

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.

1990 • 222 citations

Axenic cultivation and characterization ofLeishmania mexicanaamastigote-like forms

1992 • 187 citations

Isolation and characterization of infective and non-infective clones of Leishmania tropica

1983 • 151 citations

The Developmental Expression of A2 Amastigote-specific Genes Is Post-transcriptionally Mediated and Involves Elements Located in the 3′-Untranslated Region

1996 • 129 citations

[28] Application of LacZ gene fusions to postimplantation development

1993 • 125 citations

Genetic Manipulation of Kinetoplastida

1999 • 124 citations

The Multiple cpb Cysteine Proteinase Genes ofLeishmania mexicana Encode Isoenzymes That Differ in Their Stage Regulation and Substrate Preferences

1997 • 115 citations

Alpha-amanitin-resistant transcription units in trypanosomes: a comparison of promoter sequences for a VSG gene expression site and for the ribosomal RNA genes

1991 • 112 citations

Transient activity assays of the Trypanosoma brucei variant surface glycoprotein gene promoter: control of gene expression at the posttranscriptional level.

1991 • 109 citations

RNA polymerase I can mediate expression of CAT and neo protein-coding genes in Trypanosoma brucei.

1991 • 99 citations

Genetic nomenclature for Trypanosoma and Leishmania

1998 • 88 citations

Surface antigens of Leishmania mexicana amastigotes: characterization of glycoinositol phospholipids and a macrophage-derived glycosphingolipid

1994 • 84 citations

pRIBOTEX expression vector: a pTEX derivative for a rapid selection of Trypanosoma cruzi transfectants

1997 • 81 citations

Intergenic Regions between Tandem gp63 Genes Influence the Differential Expression of gp63 RNAs in Leishmania chagasi Promastigotes

1995 • 70 citations

Maturation of Polycistronic Pre-mRNA in Trypanosoma brucei: Analysis of trans Splicing and Poly(A) Addition at Nascent RNA Transcripts from the hsp70 Locus

1991 • 65 citations

Simultaneous transient expression assays of the trypanosomatid parasite Leishmania using β-galactosidase and β-glucuronidase as reporter enzymes

1991 • 56 citations

Transient expression mediated by the Trypanosoma cruzi rRNA promoter

1995 • 46 citations

Increased Expression of LD1 Genes Transcribed by RNA Polymerase I in Leishmania donovani as a Result of Duplication into the rRNA Gene Locus

1995 • 45 citations

Structural and functional characterization of the Leishmania amazonensis ribosomal RNA promoter

1996 • 41 citations

The promoter for the ribosomal RNA genes of Leishmania chagasi

1996 • 40 citations

The 3' untranslated region of the hsp 70 genes maintains the level of steady state mRNA in Trypanosoma brucei upon heat shock

1998 • 40 citations

Antigen presentation by Leishmania mexicana‐infected macrophages: activation of helper T cells by a model parasite antigen secreted into the parasitophorous vacuole or expressed on the amastigote surface

1996 • 38 citations

Leishmania mexicana promastigotes induce cytotoxic T lymphocytes in vivo that do not recognize infected macrophages

1993 • 29 citations

Genetic control of the immune response in mice to Leishmania mexicana surface protease.

1991 • 23 citations

Trypanosoma brucei: A Preferential Splicing at the Inverted Polyadenylation Site of the VSG mRNA Provides Further Evidence for Coupling between Trans-splicing and Polyadenylation

1995 • 11 citations