Transcriptional activation of the Klebsiella pneumoniae nitrogenase promoter may involve DNA loop formation

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals

1980 • 1,052 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1985 • 686 citations

Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter

1986 • 444 citations

Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: evidence that the ntrA product is a sigma factor.

1985 • 352 citations

REGULATION OF NITROGEN FIXATION GENES

1986 • 345 citations

Transcription of glnA by purified Escherichia coli components: core RNA polymerase and the products of glnF, glnG, and glnL.

1985 • 335 citations

Kinked DNA in crystalline complex with EcoRI endonuclease

1984 • 303 citations

Upstream activator sequences are present in the promoters of nitrogen fixation genes

1986 • 293 citations

Sequence and domain relationships of ntrC and nifA from Klebsiella pneumoniae: homologies to other regulatory proteins.

1986 • 283 citations

Yeast promoters: Positive and negative elements

1984 • 227 citations

The nif promoters of Klebsiella pneumoniae have a characteristic primary structure

1983 • 223 citations

Expression of glnA in Escherichia coli is regulated at tandem promoters.

1985 • 215 citations

Role of the nifA gene product in the regulation of nif expression in Klebsiella pneumoniae

1981 • 207 citations

Analysis of regulation of Klebsiella pneumoniae nitrogen fixation (nif) gene cluster with gene fusions

1980 • 188 citations

Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae

1983 • 173 citations

The DNA loop model for ara repression: AraC protein occupies the proposed loop sites in vivo and repression-negative mutations lie in these same sites.

1986 • 167 citations

DNA loops induced by cooperative binding of λ repressor

1986 • 165 citations

Nitrogen fixation specific regulatory genes ofKlebsiella pneumoniaeandRhizobium melilotishare homology with the general nitrogen regulatory genentrCofK. pneumoniae

1985 • 160 citations

Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae

1983 • 150 citations

A phage repressor–operator complex at 7 Å resolution

1985 • 140 citations

Nitrogen control of the nif regulon in Klebsiella pneumoniae: involvement of the ntrA gene and analogies between ntrC and nifA.

1983 • 125 citations

Tandem promoters determine regulation of theKlebsiella pneumoniaeglutamine synthetase (glnA) gene

1984 • 116 citations

Bending of promoter DNA on binding of heat shock transcription factor

1986 • 101 citations

Synthetic lac operator mediates repression through lac repressor when introduced upstream and downstream from lac promoter.

1986 • 87 citations

Enhancers and eukaryotic gene expression

1984 • 83 citations

Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region.

1983 • 81 citations

Two operator sites separated by 599 base pairs are required for deoR repression of the deo operon of Escherichia coli.

1985 • 79 citations

Overproduction of phage Lambda repressor under control of the lac promotor of Escherichia coli

1976 • 75 citations

Site-directed mutagenesis of theKlebsiella pneumoniae nifLandnifHpromoters andin vivoanalysis of promoter activity

1985 • 71 citations

Nitrogen fixation by Klebsiella pneumoniae is inhibited by certain multicopy hybrid nif plasmids

1983 • 70 citations

Activation of theBradyrhizobium japonicum nifH and nifDKoperons is dependent on promoter-upstream DNA sequences

1986 • 69 citations

Deletion analysis of the Klebsiella pneumoniae nitrogenase promoter: importance of spacing between conserved sequences around positions -12 and -24 for activation by the nifA and ntrC (glnG) products

1986 • 65 citations

Requirements for transcriptional activation in vitro of the nitrogen‐regulated gInA and nifLA promoters from Klebsiella pneumoniae: dependence on activator concentration

1987 • 61 citations

Interaction of purified NtrC protein with nitrogen regulated promoters from Klebsiella pneumoniae

1985 • 49 citations

Mutational analysis of the Klebsiella pneumoniae nitrogenase promoter: sequences essential for positive control by nifA and ntrC (glnG) products

1985 • 47 citations

Regulation of the operon encoding ribonucleotide reductase in Escherichia coli: evidence for both positive and negative control.

1986 • 45 citations

Mutations affecting regulation of the Klebsiella pneumoniae nifH (nitrogenase reductase) promotor

1984 • 41 citations

Visualization of cAMP receptor protein-induced DNA kinking by electron microscopy

1984 • 27 citations

Deletion loop mutagenesis of the nifL promoter from Klebsiella pneumoniae: role of the -26 to -12 region in promoter function

1986 • 21 citations

Frameshifts close to the Klebsiella pneumoniae nifH promoter prevent multicopy inhibition by hybrid nifH plasmids

1987 • 13 citations