Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 • 1,762 citations

Identification of Epoxyeicosatrienoic Acids as Endothelium-Derived Hyperpolarizing Factors

1996 • 1,226 citations

Molecular Cloning and Expression of CYP2J2, a Human Cytochrome P450 Arachidonic Acid Epoxygenase Highly Expressed in Heart

1996 • 469 citations

A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture.

1991 • 399 citations

Cytochrome P450 and the arachidonate cascade ¹

1992 • 288 citations

Direct Demonstration of P-Selectin– and VCAM-1–Dependent Mononuclear Cell Rolling in Early Atherosclerotic Lesions of Apolipoprotein E–Deficient Mice

1999 • 266 citations

Epoxyeicosatrienoic Acids and Dihydroxyeicosatrienoic Acids Are Potent Vasodilators in the Canine Coronary Microcirculation

1998 • 248 citations

Molecular Cloning, Expression, and Functional Significance of a Cytochrome P450 Highly Expressed in Rat Heart Myocytes

1997 • 228 citations

Endothelium-Derived Hyperpolarizing Factors and Vascular Cytochrome P450 Metabolites of Arachidonic Acid in the Regulation of Tone

1999 • 211 citations

Synthesis of hydroxyeicosatetraenoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells

1996 • 161 citations

14,15-Epoxyeicosatrienoic acid metabolism in endothelial cells.

1993 • 97 citations

Expression of Cytochrome P450s and Microsomal Epoxide Hydrolase in Primary Cultures of Human Umbilical Vein Endothelial Cells

1994 • 87 citations

Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta

1991 • 85 citations

Atherogenic concentrations of low-density lipoprotein enhance endothelial cell generation of epoxyeicosatrienoic acid products.

1990 • 62 citations

ORIGIN AND FUNCTION OF EPOXYEICOSATRIENOIC ACIDS IN VASCULAR ENDOTHELIAL CELLS: MORE THAN JUST ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR?

1998 • 49 citations

Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice

1998 • 44 citations

Human Umbilical Vein Endothelial Cells Express P450 2C8 mRNA: Cloning of Endothelial P450 Epoxygenase

1996 • 39 citations

Inhibitors of cytochrome P-450 augment fever induced by interleukin-1 beta

1996 • 25 citations