Initial Antigen Encounter Programs CD8+ T Cells Competent to Develop into Memory Cells That Are Activated in an Antigen-Free, IL-7- and IL-15-Rich Environment

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

2000 • 1,596 citations

Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

2000 • 1,578 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

2002 • 962 citations

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

2001 • 861 citations

Control of Homeostasis of CD8 ⁺ Memory T Cells by Opposing Cytokines

2000 • 847 citations

Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells

2002 • 783 citations

Persistence of Memory CD8 T Cells in MHC Class I-Deficient Mice

1999 • 738 citations

CD27 is required for generation and long-term maintenance of T cell immunity

2000 • 726 citations

Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution

2000 • 679 citations

Interleukin 15 Is Required for Proliferative Renewal of Virus-specific Memory CD8 T Cells

2002 • 671 citations

Naive T Cells Transiently Acquire a Memory-like Phenotype during Homeostasis-Driven Proliferation

2000 • 644 citations

Cytokine Requirements for Acute and Basal Homeostatic Proliferation of Naive and Memory CD8+ T Cells

2002 • 588 citations

Programmed contraction of CD8+ T cells after infection

2002 • 586 citations

Response of naïve and memory CD8+ T cells to antigen stimulation in vivo

2000 • 542 citations

T Cell Memory

2002 • 529 citations

Migratory Properties of Naive, Effector, and Memory Cd8+ T Cells

2001 • 514 citations

Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes Implications for Immunotherapy

2001 • 441 citations

Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes

2001 • 407 citations

Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15.

1995 • 397 citations

Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes

1999 • 393 citations

4-1BB Ligand Induces Cell Division, Sustains Survival, and Enhances Effector Function of CD4 and CD8 T Cells with Similar Efficacy

2001 • 352 citations

What messenger RNA capping tells us about eukaryotic evolution

2002 • 351 citations

Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells

2002 • 332 citations

Modelling T-cell memory by genetic marking of memory T cells in vivo

1999 • 310 citations

Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8+ T Cells

2002 • 291 citations

Characterization of the ovalbumin‐specific TCR transgenic line OT‐I: MHC elements for positive and negative selection

2000 • 279 citations

4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses

1999 • 259 citations

Interleukin-2, Interleukin-15, and Their Receptors

1998 • 198 citations

CD8+ Memory T Cells (CD44high, Ly-6C+) Are More Sensitive than Naive Cells (CD44low, Ly-6C−) to TCR/CD8 Signaling in Response to Antigen

1998 • 177 citations

Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells.

1996 • 139 citations

Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells

2011 • 130 citations

Gene Expression in Antigen-Specific CD8+ T Cells During Viral Infection

2001 • 130 citations

Interleukin‐7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells

1995 • 127 citations

Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes

2001 • 114 citations

Ly-6C is a marker of memory CD8+ T cells.

1995 • 109 citations

Exploring pathways for memory T cell generation

2001 • 105 citations

Broad Programming by IL-2 Receptor Signaling for Extended Growth to Multiple Cytokines and Functional Maturation of Antigen-Activated T Cells

2001 • 85 citations

Exploring pathways for memory T cell generation

2001 • 85 citations

JAK3 protein tyrosine kinase mediates interleukin-7-induced activation of phosphatidylinositol-3' kinase

1995 • 80 citations

Interleukin-15 and the regulation of lymphoid homeostasis

2002 • 75 citations

Differential TCR signaling and the generation of memory T cells.

1998 • 71 citations

JAK3 Janus kinase is involved in interleukin 7 signal pathway

1994 • 67 citations

Cutting Edge Commentary: Differential TCR Signaling and the Generation of Memory T Cells

1998 • 60 citations

Generation of primary tumor-specific CTL in vitro to immunogenic and poorly immunogenic mouse tumors.

1996 • 46 citations

Reversal of CD8+ T Cell Ignorance and Induction of Anti-Tumor Immunity by Peptide-Pulsed APC

2000 • 43 citations

Differential In Vivo Persistence of Two Subsets of Memory Phenotype CD8 T Cells Defined by CD44 and CD122 Expression Levels

2002 • 39 citations

IL-2 During In Vitro Priming Promotes Subsequent Engraftment and Successful Adoptive Tumor Immunotherapy by Persistent Memory Phenotypic CD8+ T Cells

2001 • 20 citations

TNF-Mediated Toxicity After Massive Induction of Specific CD8+ T Cells Following Immunization of Mice with a Tumor-Specific Peptide

2002 • 19 citations

Quantitation of Phosphotyrosine Signals in Human Prostate Cell Adhesion Sites

2000 • 12 citations

Segregation of Effector Mechanisms in a Tumour‐Specific CD8⁺ T‐Cell Clone Correlates with CD30 Expression

2001 • 5 citations