Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line

Pajek - Program for Large Network Analysis

1999 • 1,402 citations

Constructing biological knowledge bases by extracting information from text sources.

1999 • 605 citations

GENIES: a natural-language processing system for the extraction of molecular pathways from journal articles

2001 • 514 citations

EDGAR: Extraction of Drugs, Genes And Relations from the Biomedical Literature

1999 • 428 citations

Membrane-type 1 matrix metalloproteinase: a key enzyme for tumor invasion

2003 • 402 citations

Sphingosine 1-Phosphate Induces Angiogenesis: Its Angiogenic Action and Signaling Mechanism in Human Umbilical Vein Endothelial Cells

1999 • 359 citations

Sphingosine Kinase-1 Expression Correlates With Poor Survival of Patients With Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines

2005 • 321 citations

Akt-Mediated Phosphorylation of the G Protein-Coupled Receptor EDG-1 Is Required for Endothelial Cell Chemotaxis

2001 • 284 citations

MINING MEDLINE: ABSTRACTS, SENTENCES, OR PHRASES?

2001 • 246 citations

Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

2000 • 231 citations

EVENT EXTRACTION FROM BIOMEDICAL PAPERS USING A FULL PARSER

2000 • 228 citations

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

2003 • 212 citations

Identifying the Interaction between Genes and Gene Products Based on Frequently Seen Verbs in Medline Abstracts.

1998 • 201 citations

Information extraction from full text scientific articles: Where are the keywords?

2003 • 198 citations

Generation and metabolism of bioactive sphingosine‐1‐phosphate

2004 • 194 citations

The G Protein–Coupled Receptor S1P2 Regulates Rho/Rho Kinase Pathway to Inhibit Tumor Cell Migration

2005 • 179 citations

Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy

2004 • 178 citations

Urokinase plasminogen activator system: a multifunctional role in tumor progression and metastasis.

2003 • 170 citations

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-β1 in human breast cancer cells

2001 • 167 citations

Lecture Notes in Bioinformatics

2020 • 160 citations

Osteopontin Stimulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Phosphatidylinositol 3-Kinase/Akt Signaling Pathways in Breast Cancer Cells

2003 • 155 citations

Proteases in brain tumour progression

2003 • 153 citations

BIDIRECTIONAL INCREMENTAL PARSING FOR AUTOMATIC PATHWAY IDENTIFICATION WITH COMBINATORY CATEGORIAL GRAMMAR

2000 • 149 citations

Gene name ambiguity of eukaryotic nomenclatures

2004 • 147 citations

Differential Regulation of Sphingosine-1-Phosphate- and VEGF-Induced Endothelial Cell Chemotaxis

2001 • 144 citations

Toward Routine Automatic Pathway Discovery from On-line Scientific Text Abstracts.

1999 • 140 citations

Sphingosine 1-Phosphate and Isoform-specific Activation of Phosphoinositide 3-Kinase β

2001 • 132 citations

Expression of matrix metalloproteinase-9 and urinary-type plasminogen activator in Alzheimer's disease brain.

2001 • 130 citations

Proteases and Glioma Angiogenesis

2005 • 125 citations

Nrg-1 Belongs to the Endothelial Differentiation Gene Family of G Protein-coupled Sphingosine-1-phosphate Receptors

2001 • 121 citations

Distribution of information in biomedical abstracts and full-text publications

2004 • 121 citations

Vascular Endothelial Growth Factor Up-regulation via p21-activated Kinase-1 Signaling Regulates Heregulin-β1-mediated Angiogenesis

2000 • 118 citations

Extracting molecular binding relationships from biomedical text

2000 • 115 citations

Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo.

2003 • 114 citations

Glioblastoma multiforme

1974 • 104 citations

Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells

2003 • 103 citations

Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase β

2002 • 100 citations

PREDICTING THE SUB-CELLULAR LOCATION OF PROTEINS FROM TEXT USING SUPPORT VECTOR MACHINES

2001 • 89 citations

Sphingosine 1-Phosphate, Present in Serum-derived Lipoproteins, Activates Matriptase

2002 • 88 citations

Rac1-MKK3-p38-MAPKAPK2 Pathway Promotes Urokinase Plasminogen Activator mRNA Stability in Invasive Breast Cancer Cells

2002 • 88 citations

Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells

2005 • 84 citations

Inhibition of Tumor Invasion by Genomic Down-regulation of Matriptase through Suppression of Activation of Receptor-bound Pro-urokinase

2004 • 81 citations

Involvement of Phospholipase D in Sphingosine 1-Phosphate-induced Activation of Phosphatidylinositol 3-Kinase and Akt in Chinese Hamster Ovary Cells Overexpressing EDG3

2001 • 75 citations

Molecular Cloning, Tissue-Specific Expression, and Chromosomal Localization of a Novel Nerve Growth Factor-Regulated G-Protein-Coupled Receptor, nrg-1

1999 • 73 citations

Sphingosine-1-phosphate Mobilizes Intracellular Calcium and Activates Transcription Factor NF-κB in U937 Cells

1997 • 71 citations

PIES, a Protein Interaction Extraction System

2000 • 70 citations

Automatic extraction of gene and protein synonyms from MEDLINE and journal articles.

2002 • 62 citations

Signaling Mechanisms Responsible for Lysophosphatidic Acid-induced Urokinase Plasminogen Activator Expression in Ovarian Cancer Cells

2005 • 60 citations

Urokinase upregulates matrix metalloproteinase-9 expression in THP-1 monocytes via gene transcription and protein synthesis

2002 • 54 citations

Semi-automatic indexing of full text biomedical articles.

2005 • 53 citations

Role of guanine nucleotide exchange factor P-Rex-2b in sphingosine 1-phosphate-induced Rac1 activation and cell migration in endothelial cells

2005 • 52 citations

Data-poor categorization and passage retrieval for Gene Ontology Annotation in Swiss-Prot

2005 • 42 citations

Knowledge Discovery in Biology and Biotechnology Texts: A Review of Techniques, Evaluation Strategies, and Applications

2005 • 40 citations

A three-dimensional and temporo-spatial model to study invasiveness of cancer cells by heregulin and prostaglandin E2.

2001 • 38 citations

Heregulin inhibits proliferation via ERKs and phosphatidyl‐inositol 3‐kinase activation but regulates urokinase plasminogen activator independently of these pathways in metastatic mammary tumor cells

2002 • 37 citations

Identification of rat pancreatic carcinoma genes associated with lymphogenous metastasis.

2002 • 35 citations

Ambiguity of human gene symbols in LocusLink and MEDLINE: creating an inventory and a disambiguation test collection.

2003 • 31 citations

Molecular regulators of angiogenesis in the developing nervous system and adult brain tumors (Review)

2003 • 16 citations

Plasmin-independent gelatinase B (matrix metalloproteinase-9) release by monocytes under the influence of urokinase.

2001 • 14 citations

Text Mining of Full Text Articles and Creation of a Knowledge Base for Analysis of Microarray Data

2004 • 8 citations

GetItFull – A Tool for Downloading and Pre-processing Full-Text Journal Articles

2006 • 5 citations