Spontaneous Pain, Both Neuropathic and Inflammatory, Is Related to Frequency of Spontaneous Firing in Intact C-Fiber Nociceptors

Quantitative assessment of tactile allodynia in the rat paw

1994 • 6,953 citations

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1988 • 4,963 citations

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

1992 • 3,001 citations

Textbook of pain

1999 • 2,566 citations

Behavioral signs of ongoing pain and cold allodynia in a rat model of neuropathic pain

1994 • 803 citations

Conduction velocity is related to morphological cell type in rat dorsal root ganglion neurones.

1985 • 749 citations

Beyond Neurons: Evidence That Immune and Glial Cells Contribute to Pathological Pain States

2002 • 723 citations

Activating Transcription Factor 3 (ATF3) Induction by Axotomy in Sensory and Motoneurons: A Novel Neuronal Marker of Nerve Injury

2000 • 718 citations

Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity

1994 • 685 citations

Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat

1986 • 561 citations

Potent Analgesic Effects of GDNF in Neuropathic Pain States

2000 • 506 citations

The cytokine network of Wallerian degeneration: tumor necrosis factor-alpha, interleukin-1alpha, and interleukin-1beta.

2002 • 476 citations

Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury

2000 • 433 citations

The Cytokine Network of Wallerian Degeneration: Tumor Necrosis Factor-α, Interleukin-1α, and Interleukin-1β

2002 • 432 citations

Early Onset of Spontaneous Activity in Uninjured C-Fiber Nociceptors after Injury to Neighboring Nerve Fibers

2001 • 409 citations

Comparison of three rodent neuropathic pain models

1997 • 407 citations

Aβ-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals

2004 • 362 citations

Membrane Potential Oscillations in Dorsal Root Ganglion Neurons: Role in Normal Electrogenesis and Neuropathic Pain

1999 • 309 citations

Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy

1992 • 286 citations

Uninjured C-Fiber Nociceptors Develop Spontaneous Activity and α-Adrenergic Sensitivity Following L₆ Spinal Nerve Ligation in Monkey

1999 • 280 citations

Increased sensitivity of injured and adjacent uninjured rat primary sensory neurons to exogenous tumor necrosis factor-alpha after spinal nerve ligation.

2003 • 274 citations

Pathophysiology of damaged nerves in relation to chronic pain

1999 • 269 citations

Mechanical hyperalgesia after an L5 spinal nerve lesion in the rat is not dependent on input from injured nerve fibers

2000 • 269 citations

Increased Sensitivity of Injured and Adjacent Uninjured Rat Primary Sensory Neurons to Exogenous Tumor Necrosis Factor-α after Spinal Nerve Ligation

2003 • 256 citations

Contributions of injured and intact afferents to neuropathic pain in an experimental rat model

1996 • 235 citations

The Presence and Role of the Tetrodotoxin-Resistant Sodium Channel Na_v1.9 (NaN) in Nociceptive Primary Afferent Neurons

2002 • 233 citations

Cell loss in lumbar dorsal root ganglia and transganglionic degeneration after sciatic nerve resection in the rat

1986 • 224 citations

Similar Electrophysiological Changes in Axotomized and Neighboring Intact Dorsal Root Ganglion Neurons

2003 • 221 citations

Electrophysiological differences between nociceptive and non‐nociceptive dorsal root ganglion neurones in the rat in vivo

2005 • 210 citations

Axotomized and Intact Muscle Afferents But No Skin Afferents Develop Ongoing Discharges of Dorsal Root Ganglion Origin after Peripheral Nerve Lesion

2000 • 204 citations

Association of somatic action potential shape with sensory receptive properties in guinea‐pig dorsal root ganglion neurones

1998 • 203 citations

Possible chemical contribution from chromic gut sutures produces disorders of pain sensation like those seen in man

1993 • 197 citations

Characteristics of ectopic discharges in a rat neuropathic pain model

2000 • 184 citations

trkA Is Expressed in Nociceptive Neurons and Influences Electrophysiological Properties via Nav1.8 Expression in Rapidly Conducting Nociceptors

2005 • 146 citations

A method for unbiased and efficient estimation of number and mean volume of specified neuron subtypes in rat dorsal root ganglion

1993 • 125 citations

Nerve lesions induced by macrophage activation

1992 • 121 citations

Time Course and Nerve Growth Factor Dependence of Inflammation-Induced Alterations in Electrophysiological Membrane Properties in Nociceptive Primary Afferent Neurons

2001 • 103 citations

Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent‐induced apoptosis

2001 • 103 citations

Evolution and current status of pain programs

1990 • 89 citations

Contribution of degeneration of motor and sensory fibers to pain behavior and the changes in neurotrophic factors in rat dorsal root ganglion

2004 • 80 citations

Somata of nerve-injured sensory neurons exhibit enhanced responses to inflammatory mediators

2003 • 63 citations

The Peripheral Sensory Nervous System: Dorsal Root Ganglion Neurons

2005 • 55 citations

Increased conduction velocity of nociceptive primary afferent neurons during unilateral hindlimb inflammation in the anaesthetised guinea-pig

2001 • 52 citations

Immunopharmacology of Antibiotics: Direct and Indirect Immunomodulation of Defence Mechanisms

2001 • 35 citations

The role of uninjured nerve in spinal nerve ligated rats points to an improved animal model of neuropathic pain

2003 • 26 citations

Les douleurs neuropathiques : des avancées expérimentales aux applications cliniques

2004 • 20 citations