Communication between Hin recombinase and Fis regulatory subunits during coordinate activation of Hin-catalyzed site-specific DNA inversion

A general method for rapid site-directed mutagenesis using the polymerase chain reaction

1990 • 642 citations

Crystal structure of the site-specific recombinase γδ resolvase complexed with a 34 by cleavage site

1995 • 248 citations

Hin-mediated site-specific recombination requires two 26 by recombination sites and a 60 by recombinational enhancer

1985 • 234 citations

Hin Recombinase Bound to DNA: the Origin of Specificity in Major and Minor Groove Interactions

1994 • 206 citations

G inversion in bacteriophage Mu DNA is stimulated by a site within the invertase gene and a host factor

1985 • 204 citations

Three-dimensional structure of the E. coli DMA-binding protein FIS

1991 • 166 citations

The Hin Invertasome: Protein-Mediated Joining of Distant Recombination Sites at the Enhancer

1990 • 158 citations

Variable Structures of Fis-DNA Complexes Determined by Flanking DNA – Protein Contacts

1996 • 158 citations

Transposition of Phage Mu DNA

1996 • 150 citations

The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding.

1991 • 148 citations

Processive recombination by the phage Mu Gin system: Implications for the mechanisms of DNA strand exchange, DNA site alignment, and enhancer action

1990 • 141 citations

Isolation of the gene encoding the Hin recombinational enhancer binding protein.

1988 • 132 citations

Isolation and characterization of unusual gin mutants.

1988 • 120 citations

Escherichia coli host factor for site-specific DNA inversion: cloning and characterization of the fis gene.

1988 • 110 citations

DNA looping and the helical repeat in vitro and in vivo: effect of HU protein and enhancer location on Hin invertasome assembly.

1993 • 103 citations

Fis binding to the recombinational enhancer of the Hin DNA inversion system.

1987 • 99 citations

The Interwoven Architecture of the Mu Transposase Couples DNA Synapsis to Catalysis

1996 • 99 citations

DNA inversions in phages and bacteria

1992 • 97 citations

Mu Transpositional Recombination: Donor DNA Cleavage and Strand Transfer in trans by the Mu Transposase

1996 • 95 citations

The functional subunit of a dimeric transcription activator protein depends on promoter architecture.

1994 • 94 citations

Spatial relationship of the Fis binding sites for Hin recombinational enhancer activity

1987 • 90 citations

Processive Recombination by Wild-type Gin and an Enhancer-independent Mutant

1994 • 90 citations

Roles of supercoiled DNA structure in DNA transactions

1992 • 89 citations

Three-Site Synapsis during Mu DNA Transposition: A Critical Intermediate Preceding Engagement of the Active Site

1996 • 88 citations

Configuration of DNA strands and mechanism of strand exchange in the Hin invertasome as revealed by analysis of recombinant knots.

1991 • 85 citations

Identification of the functional subunit of a dimeric transcription activator protein by use of oriented heterodimers

1993 • 77 citations

Intermediates in Hin-mediated DNA inversion: a role for Fis and the recombinational enhancer in the strand exchange reaction.

1989 • 76 citations

Gin-mediated DNA inversion: product structure and the mechanism of strand exchange.

1988 • 75 citations

Analysis of strand exchange and DNA binding of enhancer-independent Gin recombinase mutants.

1993 • 67 citations

Enhancer-independent mutants of the Cin recombinase have a relaxed topological specificity.

1988 • 67 citations

Mechanism of site-specific DNA inversion in bacteria

1991 • 65 citations

The DNA invertase Gin of phage Mu: formation of a covalent complex with DNA via a phosphoserine at amino acid position 9.

1988 • 64 citations

Roles of supercoiled DNA structure in DNA transactions

1992 • 63 citations

DNA-binding properties of the Hin recombinase

1989 • 62 citations

Model for a DNA-mediated synaptic complex suggested by crystal packing of gamma delta resolvase subunits.

1994 • 62 citations

Model for a DNA-mediated synaptic complex suggested by crystal packing of gamma delta resolvase subunits.

1994 • 60 citations

The transactivation region of the Fis protein that controls site-specific DNA inversion contains extended mobile beta -hairpin arms

1997 • 57 citations

Refinement of γ δ resolvase reveals a strikingly flexible molecule

1994 • 55 citations

The Hin dimer interface is critical for Fis-mediated activation of the catalytic steps of site-specific DNA inversion

1996 • 53 citations

Alignment of recombination sites in Hin-mediated site-specific DNA recombination.

1991 • 51 citations

Protein-protein interactions directing resolvase site-specific recombination: a structure-function analysis.

1993 • 49 citations

Catalytic residues of gamma delta resolvase act in cis.

1995 • 47 citations

Positional Information within the Mu Transposase Tetramer: Catalytic Contributions of Individual Monomers

1996 • 37 citations

Location, degree, and direction of DNA bending associated with the Hin recombinational enhancer sequence and Fis-enhancer complex

1997 • 29 citations

Enhancer-independent variants of phage Mu transposase: enhancer-specific stimulation of catalytic activity by a partner transposase.

1995 • 23 citations

Analysis of subunit interaction by introducing disulfide bonds at the dimerization domain of Hin recombinase.

1994 • 14 citations

Role of arginine‐43 and arginine‐69 of the Hin recombinase catalytic domain in the binding of Hin to the hix DNA recombination sites

1997 • 10 citations

Proteins that promote DNA inversion and deletion

1994 • 9 citations

|Site-specific recombinases and their interactions with DNA

1995 • 8 citations