Glutamate Modulation of Dopamine Measured in Vivo with Positron Emission Tomography (PET) and 11C-Raclopride in Normal Human Subjects

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

1994 • 3,182 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-¹¹C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

1990 • 1,412 citations

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Subanesthetic Doses of Ketamine Stimulate Psychosis in Schizophrenia

1995 • 891 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1992 • 832 citations

A glutamatergic corticostriatal path?

1977 • 487 citations

An N-methylaspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine?

1985 • 457 citations

Kinetic Analysis of Central [¹¹C]Raclopride Binding to D₂-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis

1989 • 454 citations

NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine

1996 • 450 citations

Ketamine activates psychosis and alters limbic blood flow in schizophrenia

1995 • 438 citations

Dissociative anesthesia: further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581.

1966 • 389 citations

Specific [3H]phencyclidine binding in rat central nervous system.

1979 • 382 citations

Imaging endogenous dopamine competition with [¹¹C]raclopride in the human brain

1994 • 378 citations

The Prefrontal Cortex Regulates the Basal Release of Dopamine in the Limbic Striatum: An Effect Mediated by Ventral Tegmental Area

1996 • 365 citations

The N-methyl-d-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias

1995 • 306 citations

Striatal binding of the PET ligand ¹¹C‐raclopride is altered by drugs that modify synaptic dopamine levels

1993 • 285 citations

Serotonergic Function in Obsessive-Compulsive Disorder

1992 • 263 citations

Interaction of phencyclidine ("angel dust") with a specific receptor in rat brain membranes.

1979 • 263 citations

Serotonergic modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis

1995 • 216 citations

GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography

1992 • 211 citations

Reproducibility of repeated measures of carbon-11-raclopride binding in the human brain.

1993 • 183 citations

Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies

1990 • 176 citations

Effects of Blood Flow on [¹¹C]Raclopride Binding in the Brain: Model Simulations and Kinetic Analysis of PET Data

1994 • 171 citations

Effects of age and gender on CNS serotonergic responsivity in normal adults

1990 • 168 citations

In vivo characterization of locally applied dopamine uptake inhibitors by striatal microdialysis

1990 • 159 citations

Amphetamine‐stimulated dopamine release competes in vivo for [¹²³I]IBZM binding to the D2 receptor in nonhuman primates

1992 • 157 citations

Phencyclidine and ketamine intoxication: a study of four populations of recreational users.

1978 • 132 citations

Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects.

1993 • 128 citations

Effects of amphetamine on local cerebral metabolism in normal and schizophrenic subjects as determined by positron emission tomography

1987 • 103 citations

Differentiation of Radioligand Delivery and Binding in the Brain: Validation of a Two-Compartment Model for [¹¹C]Flumazenil

1991 • 94 citations

Properties of the optical isomers and metabolites of ketamine on the high affinity transport and catabolism of monoamines

1981 • 92 citations

Amphetamine induced decreases in (¹⁸F)‐N‐methylspiroperidol binding in the baboon brain using positron emission tomography (PET)

1991 • 91 citations

Excitatory Amino Acid Receptors in Schizophrenia

1993 • 90 citations

Serotonergic modulation of dopamine measured with [11C]raclopride and PET in normal human subjects

1997 • 75 citations

Alterations in local cerebral glucose utilization induced by phencyclidine

1987 • 68 citations

Delayed regional metabolic actions of phencyclidine

1993 • 67 citations

Phencyclidine and the midbrain dopamine system: Electrophysiology and behavior

1994 • 61 citations

Serotonergic function in obsessive-compulsive disorder

1996 • 59 citations

Inhibition of mammalian brain acetylcholinesterase by ketamine

1974 • 56 citations

The chiral forms of ketamine as probes for NMDA receptor functions in humans

1991 • 44 citations

PET studies of [18F]methyl-MK-801, a potential NMDA receptor complex radioligand

1991 • 40 citations

18F-desmethoxyfallypride: A fluorine-18 labeled radiotracer with properties similar to carbon-11 raclopride for pet imaging studies of dopamine D2 receptors

1996 • 39 citations

Electrophysiological evidence for excitatory amino acid receptors in the rat supraoptic nucleus in vitro

1991 • 27 citations