H-Ras Signals to Cytoskeletal Machinery in Induction of Integrin-Mediated Adhesion of T Cells

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.

1981 • 2,281 citations

Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration

1995 • 1,525 citations

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules.

1995 • 1,202 citations

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

1997 • 1,064 citations

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

1993 • 896 citations

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

1993 • 771 citations

Lymphocyte interactions with endothelial cells

1992 • 689 citations

Leucocyte-endothelial interactions and regulation of leucocyte migration

1994 • 584 citations

Chemoattractant signaling and leukocyte activation

1995 • 510 citations

Suppression of Integrin Activation: A Novel Function of a Ras/Raf-Initiated MAP Kinase Pathway

1997 • 501 citations

Role of Rho in Chemoattractant-Activated Leukocyte Adhesion Through Integrins

1996 • 494 citations

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.

1993 • 470 citations

Ras effectors

1996 • 445 citations

Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion

1993 • 437 citations

Integrin Activation by R-ras

1996 • 414 citations

Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes

1993 • 412 citations

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion.

1992 • 383 citations

Control of actin dynamics in cell motility

1997 • 337 citations

Activated Conformations of Very Late Activation Integrins Detected by a Group of Antibodies (HUTS) Specific for a Novel Regulatory Region(355-425) of the Common β1 Chain

1996 • 298 citations

Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venules.

1993 • 271 citations

Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathway.

1995 • 265 citations

Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells.

1996 • 265 citations

Ins and outs of LFA-1

1995 • 260 citations

T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1.

1996 • 249 citations

Profilins as regulators of actin dynamics

1997 • 205 citations

Profilin: At the crossroads of signal transduction and the actin cytoskeleton

1994 • 172 citations

Extracellular Ca2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion

1994 • 148 citations

Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells.

1994 • 129 citations

Alpha 4 beta 7 integrin mediates B cell binding to fibronectin and vascular cell adhesion molecule-1. Expression and function of alpha 4 integrins on human B lymphocytes.

1993 • 128 citations

Localization of a Binding Site for Phosphatidylinositol 4,5-Bisphosphate on Human Profilin

1995 • 117 citations

Regulating integrin-mediated adhesion: one more function for PI 3-kinase?

1996 • 115 citations

Cellular polarization induced by chemokines: a mechanism for leukocyte recruitment?

1996 • 104 citations

Getting integrins into shape: recent insights into how integrin activity is regulated by conformational changes

1996 • 94 citations

HEPATIC EXPRESSION OF MACROPHAGE INFLAMMATORY PROTEIN-1?? AND MACROPHAGE INFLAMMATORY PROTEIN-1?? AFTER LIVER TRANSPLANTATION1

1996 • 90 citations

Phosphatidylinositol 4,5‐bisphosphate specifically stimulates PP60^c‐src catalyzed phosphorylation of gelsolin and related actin‐binding proteins

1997 • 86 citations

Isolation and culture of synovial microvascular endothelial cells. Characterization and assessment of adhesion molecule expression

1992 • 85 citations

Promiscuous Presentation and Recognition of Nucleosomal Autoepitopes in Lupus: Role of Autoimmune T Cell Receptor α Chain

1998 • 84 citations

The Role of Profilin in Actin Polymerization and Nucleotide Exchange

1998 • 82 citations

Lymphocyte function-associated antigen 1 dominates very late antigen 4 in binding of activated T cells to endothelium.

1993 • 76 citations

Constitutive Chemokine Production Results in Activation of Leukocyte Function-Associated Antigen-1 on Adult T-Cell Leukemia Cells

1998 • 75 citations

Probing the phosphoinositide 4,5-bisphosphate binding site of human profilin I

1998 • 65 citations

Signaling mechanisms and the activation of leukocyte integrins

1997 • 64 citations

CD7-mediated regulation of integrin adhesiveness on human T cells involves tyrosine phosphorylation-dependent activation of phosphatidylinositol 3-kinase.

1997 • 63 citations

Heparan sulfate proteoglycan on leukemic cells is primarily involved in integrin triggering and its mediated adhesion to endothelial cells.

1996 • 62 citations

Distinct phenotype of leukemic T cells with various tissue tropisms.

1997 • 58 citations

Heparan sulfate proteoglycan on endothelium efficiently induces integrin-mediated T cell adhesion by immobilizing chemokines in patients with rheumatoid synovitis

1998 • 52 citations

Regulation of endothelial cell adhesion by profilin

1997 • 50 citations

Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells.

1998 • 38 citations

Membrane recruitment of Raf-1 is not the only function of Ras in Raf-1 activation

1997 • 36 citations

Localization of actobindin, profilin I, profilin II, and phosphatidylinositol-4,5-bisphosphate (PIP2) inAcanthamoeba castellanii

1998 • 35 citations

Structure‐function analysis of the human integrin VLA‐4 (α4/β1)

1991 • 20 citations

Evidence for the Involvement of Phosphatidylinositol 4,5-Bisphosphate 3-Kinase in CD18-Mediated Adhesion of Human Neutrophils to Fibrinogen

1997 • 20 citations

Intracellular signaling pathways and the regulation of cell adhesion.

1996 • 11 citations

Constitutive Chemokine Production Results in Activation of Leukocyte Function-Associated Antigen-1 on Adult T-Cell Leukemia Cells

1998 • 8 citations

Modulation of LFA-1 surface antigen expression by activated H-ras oncogene in EBV-infected human B-lymphoblast cells.

1991 • 8 citations