Vaccination-Induced Autoimmune Vitiligo Is a Consequence of Secondary Trauma to the Skin

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells

2003 • 919 citations

Does the Immune System See Tumors as Foreign or Self?

2003 • 746 citations

gp100/pmel 17 Is a Murine Tumor Rejection Antigen: Induction of “Self”-reactive, Tumoricidal T Cells Using High-affinity, Altered Peptide Ligand

1998 • 490 citations

Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

2000 • 421 citations

Vaccination with a recombinant vaccinia virus encoding a “self” antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4⁺T lymphocytes

1999 • 383 citations

Vitiligo in Patients with Melanoma

1996 • 335 citations

Immunotherapy with Dendritic Cells Directed against Tumor Antigens Shared with Normal Host Cells Results in Severe Autoimmune Disease

2000 • 258 citations

Activation of Low Avidity CTL Specific for a Self Epitope Results in Tumor Rejection But Not Autoimmunity

1998 • 248 citations

Coupling and Uncoupling of Tumor Immunity and Autoimmunity

1999 • 245 citations

Tumor immunity and autoimmunity induced by immunization with homologous DNA.

1998 • 233 citations

Progression of Armed CTL from Draining Lymph Node to Spleen Shortly After Localized Infection with Herpes Simplex Virus 1

2002 • 231 citations

Induction of anti-self-immunity to cure cancer

1995 • 207 citations

Inducing autoimmune disease to treat cancer

1999 • 187 citations

Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus protein.

1995 • 186 citations

Self-Tolerance to the Murine Homologue of a Tyrosinase-Derived Melanoma Antigen

2000 • 160 citations

Telomerase as a universal tumor-associated antigen for cancer immunotherapy

2002 • 152 citations

Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination

1997 • 145 citations

Antigens derived from melanocyte differentiation proteins: self‐tolerance, autoimmunity, and use for cancer immunotherapy

2002 • 130 citations

Induction of tissue-specific autoimmune prostatitis with prostatic acid phosphatase immunization: implications for immunotherapy of prostate cancer.

1997 • 128 citations

Dendritic cells break tolerance and induce protective immunity against a melanocyte differentiation antigen in an autologous melanoma model.

2000 • 127 citations

Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity.

2002 • 119 citations

Enabling topical immunization via microporation: a novel method for pain-free and needle-free delivery of adenovirus-based vaccines

2003 • 118 citations

A Single Heteroclitic Epitope Determines Cancer Immunity After Xenogeneic DNA Immunization Against a Tumor Differentiation Antigen

2003 • 116 citations

Genetic vaccination with 'self' tyrosinase-related protein 2 causes melanoma eradication but not vitiligo

2000 • 116 citations

Genetic immunization of mice with human tyrosinase-related protein 2: Implications for the immunotherapy of melanoma

2000 • 106 citations

Vaccine therapy of established tumors in the absence of autoimmunity.

2003 • 105 citations

Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity

2003 • 99 citations

alpha-Fetoprotein-specific tumor immunity induced by plasmid prime-adenovirus boost genetic vaccination.

2001 • 98 citations

The risk of autoimmunity associated with tumor immunotherapy

2001 • 87 citations

HER-2/neu Oncogenic Protein: Issues in Vaccine Development

1998 • 80 citations

Redundant and Alternative Roles for Activating Fc Receptors and Complement in an Antibody-Dependent Model of Autoimmune Vitiligo

2002 • 73 citations

Induction of CD8 T Cells by Vaccination with Recombinant Adenovirus Expressing Human Papillomavirus Type 16 E5 Gene Reduces Tumor Growth

2000 • 71 citations

Quantitative analysis of CEA expression in colorectal adenocarcinoma and serum: Lack of correlation

1997 • 64 citations

Genetic immunization with a melanocytic self-antigen linked to foreign helper sequences breaks tolerance and induces autoimmunity and tumor immunity

2002 • 46 citations

Dendritic Cell-Derived IL-12 Is Not Required for the Generation of Cytotoxic, IFN-γ-Secreting, CD8+ CTL In Vivo

2001 • 43 citations

Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.

2000 • 41 citations

High-Affinity HLA-A(*)02.01 Peptides from Parathyroid Hormone-Related Protein Generate In Vitro and In Vivo Antitumor CTL Response Without Autoimmune Side Effects

2002 • 35 citations

Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma

1998 • 32 citations

Immunogene Therapy for Murine Melanoma Using Recombinant Adenoviral Vectors Expressing Melanoma-Associated Antigens

2000 • 31 citations