Leptin does not affect adipocyte glucose metabolism: Studies in fresh and cultured adipocytes

Methods of Enzymatic Analysis

1975 • 20,446 citations

Methods of Enzymatic Analysis

1974 • 6,512 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

1995 • 3,730 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Role of leptin in the neuroendocrine response to fasting

1996 • 3,106 citations

Identification of targets of leptin action in rat hypothalamus.

1996 • 1,502 citations

Regional adiposity and morbidity.

1994 • 1,135 citations

Leptin: The Tale of an Obesity Gene

1996 • 987 citations

Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.

1991 • 980 citations

Specificity of Leptin Action on Elevated Blood Glucose Levels and Hypothalamic Neuropeptide Y Gene Expression in ob/ob Mice

1996 • 873 citations

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells

1996 • 751 citations

Modulation of Insulin Activities by Leptin

1996 • 733 citations

Acute stimulation of glucose metabolism in mice by leptin treatment

1997 • 717 citations

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

1995 • 716 citations

Direct antidiabetic effect of leptin through triglyceride depletion of tissues

1997 • 664 citations

Expression of the Functional Leptin Receptor mRNA in Pancreatic Islets and Direct Inhibitory Action of Leptin on Insulin Secretion

1997 • 511 citations

Leptin Impairs Metabolic Actions of Insulin in Isolated Rat Adipocytes

1997 • 463 citations

Human Obese Gene Expression: Adipocyte-Specific Expression and Regional Differences in the Adipose Tissue

1995 • 434 citations

Direct effects of leptin on brown and white adipose tissue.

1997 • 377 citations

Leptin selectively decreases visceral adiposity and enhances insulin action.

1997 • 349 citations

Short Term Effects of Leptin on Hepatic Gluconeogenesis and in Vivo Insulin Action

1997 • 311 citations

Effects of Leptin on Insulin Sensitivity in Normal Rats*

1997 • 271 citations

In VitroLipolytic Effect of Leptin on Mouse Adipocytes: Evidence for a Possible Autocrine/Paracrine Role of Leptin

1997 • 264 citations

Obese Gene Expression Alters the Ability of 30A5 Preadipocytes to Respond to Lipogenic Hormones

1996 • 238 citations

Leptin stimulates glucose transport and glycogen synthesis in C 2 C 12 myotubes: evidence for a PI3-kinase mediated effect

1997 • 207 citations

Leptin Receptor Action in Hepatic Cells

1997 • 204 citations

The effect of insulin upon glucose metabolism by adipose cells of different size

1971 • 185 citations

Leptin: A Significant Indicator of Total Body Fat but Not of Visceral Fat and Insulin Insensitivity in African-American Women

1996 • 126 citations

Low Plasma Leptin in Response to Dietary Fat in Diabetes- and Obesity-Prone Mice

1997 • 125 citations

Leptin: A Potent Inhibitor of Insulin Secretion

1997 • 106 citations

Evidence Against a Direct Effect of Leptin on Glucose Transport in Skeletal Muscle and Adipocytes

1998 • 99 citations

Lack of Effect of Leptin on Glucose Transport, Lipoprotein Lipase, and Insulin Action in Adipose and Muscle Cells¹

1998 • 80 citations

Do Leptin Receptors Play a Functional Role in the Endocrine Pancreas?

1996 • 71 citations

Effect of Regional Fat Distribution and Prader-Willi Syndrome on Plasma Leptin Levels¹

1997 • 56 citations

Augmentation ofobese(ob) Gene Expression and Leptin Secretion in Obese Spontaneously Hypertensive Rats (Obese SHR or Koletsky Rats)

1997 • 43 citations

Effect of Regional Fat Distribution and Prader-Willi Syndrome on Plasma Leptin Levels

1997 • 42 citations

Leptin Induces Tyrosine Phosphorylation of Cellular Proteins Including STAT-1 in Human Renal Adenocarcinoma Cells, ACHN

1996 • 30 citations

Plasma Leptin Concentrations Do Not Appear to Decrease Insulin-Mediated Glucose Disposal or Glucose-Stimulated Insulin Secretion in Women With Normal Glucose Tolerance

1998 • 29 citations

Preservation of intermediary metabolism in saponin-permeabilized rat adipocytes.

1988 • 23 citations

Diminished in Situ Glucose-6-Phosphate Flux in Permeabilized Adipocytes From Streptozocin-Induced Diabetic Rats

1991 • 6 citations

Persistence of disturbed adipocyte metabolism in sterptozocin-induced diabetic rats despite near-euglycemia with phlorizin

1994 • 2 citations