Down-regulation of notch target gene expression by suppressor of deltex

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1998 • 1,600 citations

Notch Signaling: From the Outside In

2000 • 958 citations

Fringe is a glycosyltransferase that modifies Notch

2000 • 846 citations

Glycosyltransferase activity of Fringe modulates Notch–Delta interactions

2000 • 686 citations

Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch

1996 • 656 citations

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

1996 • 481 citations

Ubiquitination and Endocytosis of Plasma Membrane Proteins: Role of Nedd4/Rsp5p Family of Ubiquitin-Protein Ligases

2000 • 356 citations

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats

1995 • 324 citations

Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin Ligase

2000 • 321 citations

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.

1996 • 316 citations

Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary

1994 • 254 citations

Notch signalling mediates segmentation of the Drosophila leg

1998 • 223 citations

Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos

1998 • 217 citations

The Notch signalling regulator Fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DxD

2000 • 199 citations

Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila

1995 • 199 citations

Notch signalling inDrosophila: three ways to use a pathway

1998 • 195 citations

Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos

1998 • 193 citations

Notch-Mediated Segmentation and Growth Control of the Drosophila Leg

1999 • 181 citations

Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate

2001 • 180 citations

Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing

1997 • 178 citations

Analysis of the genetic hierarchy guiding wing vein development in Drosophila

1995 • 165 citations

The Drosophila melanogaster Suppressor of deltex Gene, a Regulator of the Notch Receptor Signaling Pathway, Is an E3 Class Ubiquitin Ligase

1999 • 154 citations

Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch

1999 • 130 citations

The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe

2000 • 122 citations

Multiple levels of Notch signal regulation (Review)

2002 • 106 citations

Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling

2002 • 102 citations

Notch signaling directly controls cell proliferation in the Drosophila wing disc

2000 • 101 citations

The establishment of segmentation in theDrosophilaleg

2001 • 93 citations

Genetic Characterization of the Drosophila melanogaster Suppressor of deltex Gene: A Regulator of Notch Signaling

1998 • 73 citations

Two different activities ofSuppressor of Hairlessduring wing development inDrosophila

2000 • 61 citations

Repression by Notch is required before Wingless signalling during muscle progenitor cell development in Drosophila

1999 • 59 citations

Extra tarsal joints and abnormal cuticular polarities in various mutants ofDrosophila melanogaster

1986 • 58 citations

daughterlesscoordinates somatic cell proliferation, differentiation and germline cyst survival during follicle formation inDrosophila

2002 • 36 citations

Notch Responds Differently to Delta and Wingless in CulturedDrosophila Cells

2000 • 34 citations

Spatial regulation of DELTA expression mediates NOTCH signalling for segmentation of Drosophila legs

2001 • 20 citations