Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia

Basic local alignment search tool

1990 • 87,358 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Base-Calling of Automated Sequencer Traces UsingPhred. I. Accuracy Assessment

1998 • 6,925 citations

Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities

1998 • 5,382 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

Consed: A Graphical Tool for Sequence Finishing

1998 • 3,325 citations

National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

1996 • 1,906 citations

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

1996 • 1,464 citations

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

1991 • 915 citations

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1998 • 796 citations

A Steroid Receptor Coactivator, SRA, Functions as an RNA and Is Present in an SRC-1 Complex

1999 • 788 citations

Tumour-suppressor activity of H19 RNA

1993 • 638 citations

Does this have a familiar RING?

1996 • 632 citations

Random subcloning of sonicated DNA: Application to shotgun DNA sequence analysis

1983 • 605 citations

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

1998 • 445 citations

B-Cell Chronic Lymphocytic Leukemia: A Bird of a Different Feather

1999 • 408 citations

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

1999 • 371 citations

Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma

1994 • 302 citations

MEC1 and MEC2: two new cell lines derived from B-chronic lymphocytic leukaemia in prolymphocytoid transformation

1999 • 266 citations

Somatic ATM Mutations Indicate a Pathogenic Role of ATM in B-Cell Chronic Lymphocytic Leukemia

1999 • 263 citations

Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma

1994 • 261 citations

Chromosome aberrations in B-cell chronic lymphocytic leukemia: reassessment based on molecular cytogenetic analysis

1999 • 255 citations

B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2.

1995 • 255 citations

ATM mutations in B-cell chronic lymphocytic leukemia.

1999 • 242 citations

Somatic ATM Mutations Indicate a Pathogenic Role of ATM in B-Cell Chronic Lymphocytic Leukemia

1999 • 220 citations

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia

1997 • 212 citations

Tumor suppression by RNA from the 3′ untranslated region of α-tropomyosin

1993 • 201 citations

Monosomy 13 Is Associated With the Transition of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma

1999 • 200 citations

Comparative Genomic Hybridization Analysis of Natural Killer Cell Lymphoma/Leukemia

1999 • 179 citations

Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma

1998 • 159 citations

Characterization of Nonrandom Chromosomal Gains and Losses in Multiple Myeloma by Comparative Genomic Hybridization

1998 • 153 citations

Noncoding RNA genes

1999 • 149 citations

Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia.

1998 • 142 citations

13q deletions in lymphoid malignancies

1995 • 137 citations

Cloning and Gene Mapping of the Chromosome 13q14 Region Deleted in Chronic Lymphocytic Leukemia

1997 • 130 citations

Direct DNA sequencing of PCR-amplified vector inserts following enzymatic degradation of primer and dNTPs.

1994 • 129 citations

Exhaustive mutation scanning by fluorescence-assisted mismatch analysis discloses new genotype-phenotype correlations in angiodema.

1996 • 113 citations

Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia

1996 • 112 citations

Detailed Molecular Delineation of 13q14.3 Loss in B-Cell Chronic Lymphocytic Leukemia

1998 • 101 citations

Identification of two distinct deleted regions on chromosome 13 in prostate cancer

1998 • 94 citations

The Human Genome Project—An Overview

2000 • 86 citations

Efficient detection of point mutations on color-codedstrands of target DNA.

1994 • 81 citations

The Human Genome Project?An Overview

2000 • 80 citations

5th International Workshop on Chronic Lymphocytic Leukemia

1992 • 77 citations

Analysis of alterations of oncogenes and tumor suppressor genes in chronic lymphocytic leukemia.

1994 • 77 citations

Collection of mRNA-like non-coding RNAs

1999 • 76 citations

Limiting the location of putative human prostate cancer tumor suppressor genes on chromosome 18q

2001 • 68 citations

Epstein-Barr virus (EBV) can immortalize B-cll cells activated by cytokines.

1994 • 67 citations

A cosmid and cDNA fine physical map of a human chromosome 13q14 region frequently lost in B‐cell chronic lymphocytic leukemia and identification of a new putative tumor suppressor gene, Leu5

1998 • 65 citations

Molecular Delineation of 13q Deletion Boundaries in 20 Patients With Myeloid Malignancies

1998 • 60 citations

Deletion of three distinct regions on chromosome 13q in human non-small-cell lung cancer

1997 • 59 citations

Molecular Delineation of 13q Deletion Boundaries in 20 Patients With Myeloid Malignancies

1998 • 52 citations

Limiting the location of a putative human prostate cancer tumor suppressor gene at chromosome 13q14.3

1999 • 50 citations

Construction of a 780-kb PAC, BAC, and Cosmid Contig Encompassing the Minimal Critical Deletion Involved in B Cell Chronic Lymphocytic Leukemia at 13q14.3

1997 • 45 citations

A biological role for deletions in chromosomal band 13q14 in mantle cell and peripheral t-cell lymphomas?

1999 • 42 citations

Multiple regions of deletion on chromosome arm 13q in head-and-neck squamous-cell carcinoma

1999 • 37 citations

Establishment and characterization of the tumors of chronic lymphocytic leukemia cell line in nude and scid mice

1993 • 22 citations

Exclusion of Leu1 and Leu2 genes as tumor suppressor genes in 13q14.3-deleted B-CLL

1999 • 19 citations

Molecular Pathogenesis of B-Cell Chronic Lymphocytic Leukemia: Analysis of 13q14 Chromosomal Deletions

2000 • 12 citations