Carnitine inhibits arachidonic acid turnover, platelet function, and oxidative stress

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?

1994 • 3,002 citations

Flow Cytometric Analysis of Respiratory Burst Activity in Phagocytes With Hydroethidine and 2′,7′-Dichlorofluorescin

1990 • 869 citations

Fatty acid import into mitochondria

2000 • 753 citations

CARNITINE

1988 • 610 citations

Methods of Detection of Vascular Reactive Species

2001 • 547 citations

Arachidonic acid as a bioactive molecule

2001 • 520 citations

Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

1998 • 489 citations

Hydrogen Peroxide Is Involved in Collagen-Induced Platelet Activation

1998 • 310 citations

A role for inositol triphosphate in intracellular Ca2+ mobilization and granule secretion in platelets.

1985 • 263 citations

Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation.

1994 • 251 citations

Oxygen Free Radicals and Platelet Activation

1997 • 236 citations

Arachidonic Acid and Phosphorylation Synergistically Induce a Conformational Change of p47 to Activate the Phagocyte NADPH Oxidase

2000 • 235 citations

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C

1995 • 228 citations

Lucigenin (Bis-N-methylacridinium) as a Mediator of Superoxide Anion Production

1997 • 220 citations

NADPH oxidase of neutrophils

1996 • 208 citations

Nutritional regulation of cellular phosphatidylinositol

1987 • 206 citations

Involvement of NADH/NADPH Oxidase in Human Platelet ROS Production

2001 • 198 citations

Superoxide anion formation from lucigenin: an electron spin resonance spin‐trapping study

1997 • 192 citations

Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human platelets.

1993 • 191 citations

L -propionyl-carnitine as superoxide scavenger, antioxidant, and DNA cleavage protector.

2000 • 182 citations

Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase

1995 • 172 citations

Platelet Activation by Superoxide Anion and Hydroxyl Radicals Intrinsically Generated by Platelets That Had Undergone Anoxia and Then Reoxygenated

1997 • 149 citations

Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes.

1992 • 129 citations

The requirement for phospholipase A2 for activation of the assembled NADPH oxidase in human neutrophils

1994 • 124 citations

Free radical scavenging is involved in the protective effect of l-propionyl-carnitine against ischemia-reperfusion injury of the heart

1991 • 120 citations

Nitric oxide and its role in lipid peroxidation

1999 • 115 citations

Superoxide Anion and Hydroxyl Radical Release by Collagen-induced Platelet Aggregation - Role of Arachidonic Acid Metabolism

2000 • 98 citations

Radiolabeled Native Low-Density Lipoprotein Injected Into Patients With Carotid Stenosis Accumulates in Macrophages of Atherosclerotic Plaque

2000 • 84 citations

Myocardial carnitine and carnitine palmitoyltransferase deficiencies in patients with severe heart failure

2000 • 58 citations

Lucigenin Is a Mediator of Cytochrome C Reduction but Not of Superoxide Production

1999 • 56 citations

Vitamin E Inhibits Collagen-Induced Platelet Activation by Blunting Hydrogen Peroxide

1999 • 52 citations

Polymorphonuclear leukocyte-derived O2-reactive species activate primed platelets in human whole blood

1993 • 45 citations

[7] Nitric oxide and superoxide detection in human platelets

1999 • 37 citations

Structure and Properties of a Secretable Phospholipase A2 from Human Platelets

1990 • 32 citations

[9] Nitric oxide in platelets

1996 • 29 citations

Inhibition of platelet-activating factor synthesis in human neutrophils and platelets by propionyl-l-carnitine

1999 • 24 citations

Substrate Utilization and Work Efficiency during Submaximal Exercise in Vitamin C Depleted-Repleted Adults

1999 • 17 citations