Does innate immune privilege exist?

The Fas Death Factor

1995 • 4,070 citations

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Innate Immunity: The Virtues of a Nonclonal System of Recognition

1997 • 2,397 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Innate immunity: impact on the adaptive immune response

1997 • 1,542 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

1948 • 1,042 citations

Immunologically Privileged Sites

1978 • 815 citations

Endotoxin-induced uveitis in rats as a model for human disease

1980 • 538 citations

Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.

1991 • 470 citations

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1997 • 453 citations

Regulation of the Proinflammatory Effects of Fas Ligand (CD95L)

1998 • 391 citations

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.

1997 • 375 citations

Transgenic expression of CD95 ligand on islet β cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts

1997 • 373 citations

Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site

1999 • 360 citations

Unraveling Immune Privilege

1995 • 302 citations

ORTHOTOPIC CORNEAL TRANSPLANTATION IN MICE—EVIDENCE THAT THE IMMUNOGENETIC RULES OF REJECTION DO NOT APPLY

1992 • 298 citations

A second study of the behaviour and fate of skin homografts in rabbits: A Report to the War Wounds Committee of the Medical Research Council.

1945 • 273 citations

Immune Privilege and Immune Regulation in the Eye

1990 • 265 citations

Studies on the induction of anterior chamber‐associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor‐β

1992 • 250 citations

Cutting Edge: Role of Macrophage Migration Inhibitory Factor in Inhibiting NK Cell Activity and Preserving Immune Privilege

1998 • 249 citations

Aqueous humor contains transforming growth factor-beta and a small (less than 3500 daltons) inhibitor of thymocyte proliferation.

1990 • 234 citations

Corneal allografts fail to express Ia antigens

1979 • 227 citations

Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor

1992 • 225 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

Immune response to immunization via the anterior chamber of the eye. I. F. lymphocyte-induced immune deviation.

1977 • 208 citations

Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor.

1994 • 207 citations

Soluble Fas Ligand Is Chemotactic for Human Neutrophilic Polymorphonuclear Leukocytes

1999 • 175 citations

Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice.

1981 • 156 citations

ROLE OF FAS-FAS LIGAND INTERACTIONS IN THE IMMUNOREJECTION OF ALLOGENEIC MOUSE CORNEAL TRANSPLANTS1

1997 • 147 citations

Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens.

1980 • 139 citations

The Expression of HLA Antigens by Cells in the Human Cornea

1984 • 124 citations

Suppression of nitric oxide generated by inflammatory macrophages by calcitonin gene-related peptide in aqueous humor.

1998 • 108 citations

Isolation and characterization of a unique natural killer cell inhibitory factor present in the anterior chamber of the eye.

1996 • 107 citations

Aqueous humor induces transforming growth factor-ß (TGF-ß)-producing regulatory T-cells

1997 • 102 citations

Distinctive humoral immune responses following anterior chamber and intravenous administration of soluble antigen. Evidence for active suppression of IgG2-secreting B lymphocytes.

1990 • 97 citations

Inhibition of lymphocyte proliferation by aqueous humor.

1989 • 96 citations

Immunoregulatory properties of bone marrow-derived cells in the iris and ciliary body.

1989 • 95 citations

Immune response to immunization via the anterior chamber of the eye. II. An analysis of F1 lymphocyte-induced immune deviation.

1978 • 93 citations

T-cell mediated responses in a murine model of orthotopic corneal transplantation.

1995 • 91 citations

Alpha-Melanocyte-Stimulating Hormone Suppresses Antigen-Stimulated T Cell Production of Gamma-lnterferon

1994 • 87 citations

Immune privilege and suppression of immunogenic inflammation in the anterior chamber of the eye

1991 • 86 citations

Regional Immunity and Ocular Immune Privilege

1999 • 81 citations

The distribution and ontogeny of MHC antigens in murine ocular tissue.

1987 • 77 citations

Specific aqueous humor factors induce activation of regulatory T cells.

1999 • 76 citations

Do immunologically privileged sites require a functioning spleen?

1974 • 65 citations

Die Entwickelung der in fremden Grund versetzten lebenden Gewebe

1873 • 62 citations

Epithelium-deficient corneal allografts display immune privilege beneath the kidney capsule.

2000 • 61 citations

Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors.

1997 • 59 citations

A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation.

1998 • 59 citations

Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 1. Inhibition of T-cell activation in vitro by direct cell-to-cell contact.

2000 • 58 citations

A role for CD95 ligand in preventing graft rejection

1996 • 54 citations

Aqueous humor factors and their effect on the immune response in the anterior chamber

1990 • 47 citations

Mice deficient in tumor necrosis factor receptors p55 and p75, interleukin-4, or inducible nitric oxide synthase are susceptible to endotoxin-induced uveitis.

1998 • 44 citations

Immunologically Privileged Sites

1978 • 43 citations

Local inhibition of natural killer cell activity promotes the progressive growth of intraocular tumors.

1997 • 23 citations

Effect of aqueous humor on apoptosis of inflammatory cell types.

1999 • 21 citations

[Research on the complementary and anticomplementary power of the aqueous humor and the vitreous body of the guinea pig].

1960 • 3 citations

Deleted Work

1955 • 0 citations