Genetic and temporal control of neonatal antibody expression.

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

A better cell line for making hybridomas secreting specific antibodies

1978 • 1,649 citations

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1979 • 859 citations

Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization.

1980 • 653 citations

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

1979 • 472 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

Genetics of the Antibody Response to Dextran in Mice

1972 • 348 citations

Evidence for the clonal abortion theory of B-lymphocyte tolerance.

1975 • 293 citations

In vitro tolerance induction of neonatal murine B cells.

1976 • 281 citations

THE MECHANISM OF ANTIGENIC STIMULATION OF PRIMARY AND SECONDARY CLONAL PRECURSOR CELLS

1972 • 272 citations

Analysis of the repertoire of anti‐(4‐hydroxy‐3‐nitro‐phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti‐idiotope antibodies

1979 • 254 citations

GENETICS OF A NEW IgVH (T15 IDIOTYPE) MARKER IN THE MOUSE REGULATING NATURAL ANTIBODY TO PHOSPHORYLCHOLINE

1974 • 247 citations

Rearrangement of genetic information may produce immunoglobulin diversity

1978 • 209 citations

Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones.

1981 • 190 citations

Somatic mutation of immunoglobulin light-chain variable-region genes

1981 • 184 citations

Inherited Immunoglobulin Idiotypes of the Mouse

1977 • 168 citations

Deletions are associated with somatic rearrangement of immunoglobulin heavy chain genes

1980 • 159 citations

Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance.

1976 • 123 citations

Heterogeneity of the BALB/c antiphosphorylcholine antibody response at the precursor cell level.

1975 • 121 citations

The characterization fo the B-cell repertoire specific for the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl determinants in neonatal BALB/c mice.

1975 • 117 citations

Genetic control of antibody specificity in the mouse

1975 • 116 citations

Neonatal treatment with low doses of anti-idiotypic antibody leads to the expression of a silent clone.

1981 • 105 citations

ONTOGENY OF B-LYMPHOCYTE FUNCTION

1974 • 100 citations

Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype

1977 • 91 citations

Adaptive differentiation of murine lymphocytes. I. Both T and B lymphocytes differentiating in F1 transplanted to parental chimeras manifest preferential cooperative activity for partner lymphocytes derived from the same parental type corresponding to the chimeric host.

1978 • 84 citations

Late acquisition of a germ line antibody specificity

1976 • 81 citations

Antibody-specific immunoregulation

1977 • 66 citations

Idiotypic analysis of anti-GAT antibodies. I. Presence of common idiotypic specificities in both responder and nonresponder mice.

1978 • 65 citations

Patterned acquisition of the antibody repertoire: diversity of the hemagglutinin-specific B-cell repertoire in neonatal BALB/c mice.

1979 • 64 citations

Contribution of immunoglobulin heavy-chain variable-region genes to antibody diversity

1980 • 62 citations

Immunological unresponsiveness to native dextran B512 in young animals of dextran high responder strains is due to lack of Ig receptors expression. Evidence for a nonrandom expression of V-genes.

1978 • 62 citations

Frequency of occurrence of idiotypes associated with anti-p-azophenylarsonate antibodies arising in mice immunologically suppressed with respect to a cross-reactive idiotype.

1977 • 57 citations

Bursectomy in ovo Blocks the Generation of Immunoglobulin Diversity

1978 • 53 citations

Differential expression of an equivalent clonotype among BALB/c and C57BL/6 mice

1978 • 52 citations

The monoclonal anti-phosphorylcholine antibody response in several murine strains: genetic implications of a diverse repertoire.

1977 • 51 citations

Recovery of antibody activity on reoxidation of completely reduced polyalanyl heavy chain and its Fd fragment derived from anti-2,4-dinitrophenyl antibody

1968 • 48 citations

Antibody diversity in amphibians: inheritance of isoelectric focusing antibody patterns in isogenic frogs

1978 • 46 citations

Idiotype‐specific neonatal suppression of phosphorylcholine‐responsive B cells

1977 • 43 citations

Tolerance induction in maturing B cells.

1977 • 40 citations

Maturation of the lymphoid system. I. Induction of tolerance in neonates with a T-dependent antigen that is an obligate immunogen in adults.

1979 • 39 citations

Analysis of the primary anti-(4-hydroxy-3-nitrophenyl) acetyl (NP) responsive B cells in BALB/C and B10.D2 mice.

1980 • 36 citations

Isoelectric analysis of neonatal monofocal antibody

1973 • 35 citations

Heterogeneity of the BALB/c IgM anti-phosphorylcholine antibody response

1982 • 33 citations

Unique determinants associated with hybridoma proteins expressing a cross-reactive idiotype: frequency among individual immune sera.

1980 • 30 citations

Immature B cells as the target for in vivo tolerance induction.

1981 • 30 citations

Age-dependent changes in the relative affinity of anti-dinitrophenyl antibodies in mice.

1975 • 25 citations

In vitro tolerance induction of neonatal murine B cells as a probe for the study of B-cell diversification.

1977 • 24 citations

Hapten-specific B cell repertoire probed by hybridoma technology: selection and characterization of representative clonotypes from the antibody-forming cell pool.

1982 • 22 citations

B cell repertoire ontogeny: heritable but dissimilar development of parental and F1 repertoires.

1981 • 21 citations

Idiotype sharing by murine strains differing in immunoglobulin allotype

1978 • 12 citations

Studies of a cross-reactive idiotype associated with anti-para-azophenylarsonate antibodies of A/J mice.

1976 • 12 citations

Ontogeny of Clonal Dominance

1979 • 6 citations