Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones.

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Towards a network theory of the immune system.

1974 • 3,379 citations

Regulatory Effect of Antibody on the Immune Response

1968 • 648 citations

Suppressor T cells.

1972 • 430 citations

CROSS-IDIOTYPIC SPECIFICITY AMONG MONOCLONAL I<scp>G</scp>M PROTEINS WITH ANTI-γ-GLOBULIN ACTIVITY

1973 • 429 citations

Use of anti-idiotypic antibodies as cell-surface receptor probes

1978 • 345 citations

Antigen-Binding Myeloma Proteins of Mice

1978 • 272 citations

SUPPRESSION OF IDIOTYPIC SPECIFICITIES IN ADULT MICE BY ADMINISTRATION OF ANTIIDIOTYPIC ANTIBODY

1972 • 270 citations

Idiotypic-anti-idiotypic regulation of antibody synthesis in rabbits.

1977 • 219 citations

Idiotypic regulation of the immune system by the induction of antibodies against anti-idiotypic antibodies.

1977 • 211 citations

Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype.

1979 • 162 citations

Detection of anti‐idiotype reactive cells in the response to phosphorylcholine

1976 • 146 citations

Regulation of Immune Response by Autogenous Antibody against Receptor

1974 • 142 citations

Genetics of Immunoglobulins in the Mouse

1967 • 141 citations

Presence on idiotype-specific suppressor T cells of receptors that interact with molecules bearing the idiotype.

1977 • 130 citations

Recognition of idiotypes in lymphocyte interactions I. Idiotypic selectivity in the cooperation between T and B lymphocytes

1978 • 109 citations

Idiotypic Regulation in Immune Networks

1981 • 109 citations

Absolute frequencies of lipopolysaccharide-reactive B cells producing A5A idiotype in unprimed, streptococcal A carbohydrate-primed, anti-A5A idiotype-sensitized and anti-A5A idiotype-suppressed A/J mice.

1977 • 104 citations

Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes.

1979 • 89 citations

Production of auto-anti-idiotypic antibody during the normal immune response to TNP-ficoll. II. Hapten-reversible inhibition of anti-TNP plaque-forming cells by immune serum as an assay for auto-anti-idiotypic antibody

1979 • 89 citations

Idiotypic regulation of the immune system. Common idiotypic specificities between idiotypes and antibodies raised against anti-idiotypic antibodies in rabbits.

1979 • 88 citations

Suppression of idiotype and generation of suppressor T cells with idiotype-conjugated thymocytes.

1979 • 87 citations

Reciprocal expansions of idiotypic and anti-idiotypic clones following antigen stimulation

1979 • 77 citations

Idiotype of inulin-binding antibodies and myeloma proteins controlled by genes linked to the allotype locus of the mouse.

1976 • 77 citations

Autoregulation of an antibody response via network-induced auto-anti-idiotype

1979 • 77 citations

Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype.

1978 • 73 citations

Possible occurrence and meaning of lymphocytes bearing autoanti‐idiotypic receptors during the immune response

1978 • 59 citations

Tritium (3H) radiolabeling of protein A and antibody to high specific activity: Application to cell surface antigen radioimmunoassays

1979 • 47 citations

Immune response to levan. II. T independence of suppression of cross-reactive idiotypes by anti-idiotype antibodies.

1979 • 39 citations

Regulation of the anti-inulin antibody response by a nonallotype-linked gene.

1980 • 34 citations

Homobodies: do they exist?

1979 • 32 citations

Anti-immunoglobulin antibodies. I. Expression of cross-reactive idiotypes and Ir gene control of the response to IgG2a of the b allotype.

1980 • 29 citations

Direct and indirect suppression induced by anti-idiotype antibody in the inulin-bacterial levan antigenic system

1979 • 25 citations

Genetic and cellular regulation of the expression of specific antibody idiotypes in the anti-polyfructosan immune response.

1979 • 17 citations

Presence of plasma cells binding autologous antibody during an immune response.

1979 • 13 citations

Regulation of anti-TNP response by antiidiotypic and anti-(antiidiotypic) antibodies.

1979 • 8 citations

The Appearance of 460-Idiotype (460-Id)-Bearing Anti-TNP Antibodies Is Regulated by Suppressor T Cells Specific for 460-Id

1980 • 4 citations