Accumulation of acetylcholine receptors is a necessary condition for normal accumulation of acetylcholinesterase during in vitro neuromuscular synaptogenesis

A new and rapid colorimetric determination of acetylcholinesterase activity

1961 • 25,114 citations

PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY

1974 • 3,882 citations

A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

1964 • 3,400 citations

Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix

1992 • 1,381 citations

A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin

1993 • 1,352 citations

Membrane organization of the dystrophin-glycoprotein complex

1991 • 1,321 citations

Molecular and cellular biology of cholinesterases

1993 • 1,192 citations

Antibody to acetylcholine receptor in myasthenia gravis

1998 • 1,149 citations

Antibody to acetylcholine receptor in myasthenia gravis: Prevalence, clinical correlates, and diagnostic value

1976 • 1,123 citations

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

Synaptic structure and development: The neuromuscular junction

1993 • 846 citations

The Molecular Forms of Cholinesterase and Acetylcholinesterase in Vertebrates

1982 • 819 citations

Agrin Acts via a MuSK Receptor Complex

1996 • 653 citations

The Agrin Hypothesis

1990 • 637 citations

Neuromuscular Junction in Myasthenia Gravis: Decreased Acetylcholine Receptors

1973 • 633 citations

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction

1989 • 566 citations

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

1995 • 530 citations

Multiple forms of acetylcholinesterase and their distribution in endplate and non‐endplate regions of rat diaphragm muscle

1973 • 505 citations

Biochemistry and Metabolism of Basement Membranes

1979 • 468 citations

Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

1980 • 452 citations

Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β2

1995 • 447 citations

Myasthenic Antibodies Cross-Link Acetylcholine Receptors to Accelerate Degradation

1978 • 425 citations

Cholinesterase is associated with the basal lamina at the neuromuscular junction

1978 • 397 citations

Peroxynitrite Inhibits Glutamate Transporter Subtypes

1996 • 375 citations

Serum Globulin in Myasthenia Gravis: Inhibition of α-Bungarotoxin Binding to Acetylcholine Receptors

1974 • 365 citations

Concentration of acetylcholine receptor mRNA in synaptic regions of adult muscle fibres

1985 • 344 citations

Identification and purification of an agrin receptor from torpedo postsynaptic membranes: A heteromeric complex related to the dystroglycans

1994 • 307 citations

Agrin Is a Heparan Sulfate Proteoglycan

1995 • 281 citations

The distribution of α‐bungarotoxin binding sites on mammalian skeletal muscle developing in vivo

1977 • 266 citations

Asymmetric and globular forms of acetylcholinesterase in mammals and birds.

1979 • 263 citations

Enzymatic Detachment of Endplate Acetylcholinesterase from Muscle

1971 • 245 citations

Dystrophin-associated proteins in muscular dystrophy

1995 • 242 citations

Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions

1992 • 231 citations

Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit.

1988 • 215 citations

RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubes

1992 • 212 citations

Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex

1995 • 209 citations

MYASTHENIA GRAVIS: A SERUM FACTOR BLOCKING ACETYLCHOLINE RECEPTORS OF THE HUMAN NEUROMUSCULAR JUNCTION

1975 • 185 citations

Agrin-induced specializations contain cytoplasmic, membrane, and extracellular matrix-associated components of the postsynaptic apparatus

1989 • 163 citations

Induction by agrin of ectopic and functional postsynaptic-like membrane in innervated muscle

1997 • 157 citations

Anchorage of collagen-tailed acetylcholinesterase to the extracellular matrix is mediated by heparan sulfate proteoglycans.

1985 • 153 citations

Accelerated degradation of acetylcholine receptor from cultured rat myotubes with myasthenia gravis sera and globulins.

1977 • 150 citations

Neural induction of the 16S acetylcholinesterase in muscle cell cultures

1978 • 147 citations

Control of junctional acetylcholinesterase by neural and muscular influences in the rat.

1980 • 138 citations

Agrin-Induced Postsynaptic-like Apparatus in Skeletal Muscle Fibersin Vivo

1997 • 132 citations

Motor neurons contain agrin-like molecules.

1988 • 131 citations

The Basal Lamina of the Neuromuscular Junction

1983 • 118 citations

Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle

1997 • 110 citations

Compartmentalization of acetylcholinesterase mRNA and enzyme at the vertebrate neuromuscular junction

1993 • 106 citations

Role of the main immunogenic region of acetylcholine receptor in myasthenia gravis. An Fab monoclonal antibody protects against antigenic modulation by human sera.

1985 • 106 citations

Association of the synaptic form of acetylcholinesterase with extracellular matrix in cultured mouse muscle cells

1982 • 98 citations

Developmental regulation of 16S acetylcholinesterase and acetylcholine receptors in a mouse muscle cell line

1983 • 94 citations

Substrate-bound agrin induces expression of acetylcholine receptor epsilon-subunit gene in cultured mammalian muscle cells.

1996 • 83 citations

Early appearance of and neuronal contribution to agrin-like molecules at embryonic frog nerve-muscle synapses formed in culture

1992 • 77 citations

The putative agrin receptor binds ligand in a calcium-dependent manner and aggregates during agrin-induced acetylcholine receptor clustering

1991 • 75 citations

Developmental Regulation of Acetylcholinesterase Transcripts in the Mouse Diaphragm: Alternative Splicing and Focalization

1995 • 71 citations

Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation.

1995 • 69 citations

Agrin and the molecular choreography of synapse formation

1993 • 69 citations

Axotomy-induced neurofilament phosphorylation is inhibited in situ by micromjection of PKA and PKC inhibitors into identified lamprey neurons

1993 • 68 citations

Synthesis and Transport of Agrin-Like Molecules in Motor Neurons

1990 • 68 citations

The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies

1991 • 68 citations

Dystrophin-associated proteins and synapse formation: Is α-dystroglycan the agrin receptor?

1994 • 60 citations

Distribution and anchoring of molecular forms of acetylcholinesterase

1989 • 55 citations

Myoblast fusion and innervation with rat motor nerve alter distribution of acetylcholinesterase and its mRNA in cultures of human muscle

1995 • 54 citations

Agrin-induced reorganization of extracellular matrix components on cultured myotubes: relationship to AChR aggregation.

1990 • 53 citations

Testing the Agrin Hypothesis

1996 • 48 citations

Agrin induces α‐actinin, filamin, and vinculin to co‐localize with AChR clusters on cultured chick myotubes

1991 • 42 citations

Allelic variants of acetylcholinesterase: genetic evidence that all acetylcholinesterase forms in avian nerves and muscles are encoded by a single gene.

1988 • 42 citations

Transient Interactions between Collagen-tailed Acetylcholinesterase and Sulfated Proteoglycans Prior to Immobilization on the Extracellular Matrix

1996 • 41 citations

Action of veratridine on acetylcholinesterase in cultures of rat muscle cells

1984 • 39 citations

Nicotinic acetylcholine receptor : structure and function

1986 • 39 citations

Presynaptic or postsynaptic origin of acetylcholinesterase at neuromuscular junctions? An immunological study in heterologous nerve-muscle cultures

1986 • 30 citations

Use of a replica technique to isolate muscle cell lines defective in expressing the acetylcholine receptor.

1985 • 25 citations

Clusters of 43-kDa protein are absent from genetic variants of C2 muscle cells with reduced acetylcholine receptor expression

1989 • 22 citations

Effect of myasthenic patient sera on the number and distribution of acetylcholine receptors in muscle and nerve-muscle cultures from rat

1988 • 21 citations

Molecular Biology of Muscle and Neural Acetylcholine Receptors

1986 • 16 citations

Recombinant neuromuscular synapses

1992 • 14 citations

Former Neuritic Pathways Containing Endogenous Neural Agrin Have High Synaptogenic Activity

1995 • 14 citations

Acetylcholinesterase in Cocultures of Rat Myotubes and Spinal Cord Neurons: Effects of Collagenase and cis‐Hydroxyproline on Molecular Forms, Intra‐ and Extracellular Distribution, and Formation of Patches at Neuromuscular Contacts

1990 • 13 citations

Schwann Cells Modify Expression of Acetylcholinesterase and Butyrylcholinesterase at Rat Neuromuscular Junctions

1997 • 12 citations

Effect of sera from myasthenia gravis patients and of α-bungarotoxin on acetylcholinesterase during in vitro neuromuscular synaptogenesis

1993 • 9 citations

Erratic Deposition of Agrin during the Formation of Xenopus Neuromuscular Junctions in Culture

1995 • 6 citations

Decorin is specifically solubilized by heparin from the extracellular matrix of rat skeletal muscles

1993 • 6 citations

[26] Transferrin: Assay of myotrophic effects and method for immunocytochemical localization

1987 • 3 citations

Deleted Work

1955 • 0 citations