GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

1990 • 1,044 citations

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 • 1,031 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 845 citations

Nested expression domains of four homeobox genes in developing rostral brain

1992 • 794 citations

The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo

1994 • 786 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 727 citations

Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.

1993 • 708 citations

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

1994 • 567 citations

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

1994 • 550 citations

An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes.

1988 • 518 citations

GATA-6: A Zinc Finger Transcription Factor That Is Expressed in Multiple Cell Lineages Derived from Lateral Mesoderm

1996 • 469 citations

Cytostatic Gene Therapy for Vascular Proliferative Disorders with a Constitutively Active form of the Retinoblastoma Gene Product

1995 • 455 citations

GATA transcription factors: key regulators of hematopoiesis.

1995 • 430 citations

Production of homozygous mutant ES cells with a single targeting construct.

1992 • 418 citations

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst.

1994 • 372 citations

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

1991 • 364 citations

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.

1993 • 329 citations

A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila

1996 • 310 citations

Transcriptional Elements from the Human SP-C Gene Direct Expression in the Primordial Respiratory Epithelium of Transgenic Mice

1993 • 299 citations

Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.

1992 • 295 citations

Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of Hnf-4−/− embryos

1997 • 295 citations

HNF-3β as a regulator of floor plate development

1994 • 287 citations

Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro

1995 • 275 citations

Structure and Expression of a Smooth Muscle Cell-specific Gene, SM22α

1995 • 254 citations

GATA-5: A Transcriptional Activator Expressed in a Novel Temporally and Spatially-Restricted Pattern during Embryonic Development

1997 • 253 citations

GATA-4 is a novel transcription factor expressed in endocardium of the developing heart

1993 • 250 citations

Origin and differentiation of extraembryonic tissues in the mouse.

1983 • 233 citations

end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos

1997 • 220 citations

Investigation of cell lineage and differentiation in the extraembryonic endoderm of the mouse embryo.

1982 • 195 citations

The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells.

1994 • 186 citations

Mouse GATA-4: a Retinoic Acid-Inducible GATA-Binding Transcription Factor Expressed in Endodermally Derived Tissues and Heart

1993 • 181 citations

Production and analysis of chimeric mice

1987 • 175 citations

A Nonerythroid GATA-Binding Protein Is Required for Function of the Human Preproendothelin-1 Promoter in Endothelial Cells

1990 • 163 citations

Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis

1994 • 163 citations

Establishment and Organization of Germ Layers in the Gastrulating Mouse Embryo

2007 • 148 citations

The gene serpent has homeotic properties and specifies endoderm versus ectoderm within the Drosophila gut

1994 • 142 citations

Production of Homozygous Mutant ES Cells with a Single Targeting Construct

1992 • 140 citations

The Expression Pattern of the Chick Homeobox Gene gMHox Suggests a Role in Patterning of the Limbs and Face and in Compartmentalization of Somites

1994 • 131 citations

Investigation of cell lineage and differentiation in the extraembryonic endoderm of the mouse embryo

1982 • 117 citations

The Pem Homeobox Gene Is X-Linked and Exclusively Expressed in Extraembryonic Tissues during Early Murine Development

1994 • 115 citations

Structure and Expression of the Murine Slow/Cardiac Troponin C Gene

1989 • 111 citations

ENC-1: A Novel MammalianKelch-Related Gene Specifically Expressed in the Nervous System Encodes an Actin-Binding Protein

1997 • 95 citations

A nonerythroid GATA-binding protein is required for function of the human preproendothelin-1 promoter in endothelial cells.

1990 • 89 citations

Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity

1992 • 77 citations

Regulation of vitellogenin gene expression in transgenic Caenorhabditis elegans: short sequences required for activation of the vit-2 promoter.

1992 • 67 citations

Cloning and Characterization of the Mouse Clara Cell-Specific 10-kDa Protein Gene: Comparison of the 5′-Flanking Region with the Human, Rat, and Rabbit Gene

1993 • 48 citations

The GATA-4 Transcription Factor Transactivates the Cardiac Muscle-Specific Troponin C Promoter-Enhancer in Nonmuscle Cells

1994 • 42 citations

DNA-Protein Interactions in the Caenorhabditis elegans Embryo: Oocyte and Embryonic Factors That Bind to the Promoter of the Gut-Specific ges-1 Gene

1994 • 31 citations

Regulation of Vitellogenin Gene Expression in Transgenic Caenorhabditis elegans: Short Sequences Required for Activation of the vit-2 Promoter

1992 • 15 citations