Interaction between Virion-Bound Host Intercellular Adhesion Molecule-1 and the High-Affinity State of Lymphocyte Function-Associated Antigen-1 on Target Cells Renders R5 and X4 Isolates of Human Immunodeficiency Virus Type 1 More Refractory to Neutralization

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

Production of high-titer helper-free retroviruses by transient transfection.

1993 • 2,280 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

Atomic structure of the ectodomain from HIV-1 gp41

1997 • 1,610 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 • 1,194 citations

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

1996 • 1,058 citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

1988 • 967 citations

Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

1993 • 636 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

1988 • 412 citations

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells

1989 • 405 citations

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120

1995 • 405 citations

Evidence for Cell-Surface Association Between Fusin and the CD4-gp120 Complex in Human Cell Lines

1996 • 367 citations

Identification of the residues in human CD4 critical for the binding of HIV

1989 • 357 citations

Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates

1992 • 287 citations

Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity

1997 • 280 citations

Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1

1995 • 263 citations

Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1.

1995 • 250 citations

A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.

1988 • 248 citations

The acquisition of host-encoded proteins by nascent HIV-1

1998 • 191 citations

Syncytium-inducing (SI) phenotype suppression at seroconversion after intramuscular inoculation of a non-syncytium-inducing/SI phenotypically mixed human immunodeficiency virus population

1995 • 177 citations

Macromolecular interactions in the assembly of HIV and other retroviruses

1994 • 174 citations

Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Primary Isolates to Antibodies and CD4-Based Reagents Is Independent of Coreceptor Usage

1998 • 165 citations

Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus

1997 • 157 citations

The presence of host-derived HLA-DR1 on human immunodeficiency virus type 1 increases viral infectivity

1997 • 141 citations

Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization

1997 • 140 citations

Acquisition of host cell-surface-derived molecules by HIV-1

1996 • 139 citations

Neutralization sensitivity of human immunodeficiency virus type 1 is determined in part by the cell in which the virus is propagated

1994 • 137 citations

Neutralization of HIV-1 by F105, a human monoclonal antibody to the CD4 binding site of gp120.

1993 • 134 citations

A Sensitive Reporter Cell Line for HIV-1tatActivity, HIV-1 Inhibitors, and T Cell Activation Effects

1994 • 130 citations

Lymphocyte Locomotion and Migration

2015 • 118 citations

Inhibition of Virus Attachment to CD4+ Target Cells Is a Major Mechanism of T Cell Line–adapted HIV-1 Neutralization

1997 • 118 citations

Nonrandom association of cellular antigens with HTLV-III virions

1987 • 113 citations

Direct identification of class II histocompatibility DR proteins in preparations of human T-cell lymphotropic virus type III

1987 • 107 citations

T Cells Expressing Activated LFA-1 Are More Susceptible to Infection with Human Immunodeficiency Virus Type 1 Particles Bearing Host-Encoded ICAM-1

1998 • 106 citations

Host cell-dependent alterations in envelope components of human immunodeficiency virus type 1 virions

1997 • 100 citations

The Amount of Host HLA-DR Proteins Acquired by HIV-1 Is Virus Strain- and Cell Type-Specific

1996 • 98 citations

Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein

1995 • 92 citations

HLA Class II on HIV Particles Is Functional in Superantigen Presentation to Human T Cells: Implications for HIV Pathogenesis

1995 • 79 citations

Level of ICAM-1 Surface Expression on Virus Producer Cells Influences both the Amount of Virion-Bound Host ICAM-1 and Human Immunodeficiency Virus Type 1 Infectivity

1998 • 76 citations

Evidence that Antibody-Mediated Neutralization of Human Immunodeficiency Virus Type 1 by Sera from Infected Individuals Is Independent of Coreceptor Usage

1998 • 75 citations

HIV Acquires Functional Adhesion Receptors from Host Cells

1995 • 68 citations

Transmission of Zidovudine-Resistant Human Immunodeficiency Virus Type 1 Variants Following Deliberate Injection of Blood from a Patient with AIDS: Characteristics and Natural History of the Virus

1995 • 67 citations

Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1

1995 • 63 citations

Role of cellular adhesion molecules in HIV type 1 infection and their impact on virus neutralization.

1998 • 59 citations

Coreceptor Utilization by Human Immunodeficiency Virus Type 1 Is Not a Primary Determinant of Neutralization Sensitivity

1998 • 55 citations

HIV Type 1 Grown on Interferon γ-Treated U937 Cells Shows Selective Increase in Virion-Associated Intercellular Adhesion Molecule 1 and HLA-DR and Enhanced Infectivity for CD4-Negative Cells

1995 • 53 citations

Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein

1995 • 49 citations

The role of lymphoid organs in the immunopathogenesis of HIV infection

1993 • 38 citations

The role of lymphoid organs in the immunopathogenesis of HIV infection

1992 • 36 citations

Involvement of human leukocyte antigen class I molecules in human immunodeficiency virus infection of CD4-positive cells

1994 • 32 citations

Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses

1996 • 30 citations

Adhesion Mediated by Intercellular Adhesion Molecule 1 Attenuates the Potency of Antibodies That Block HIV-1 gp160-Dependent Syncytium Formation

1994 • 26 citations