Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy

1986 • 1,694 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Infection of HTLV-III/LAV in HTLV-I-Carrying Cells MT-2 and MT-4 and Application in a Plaque Assay

1985 • 860 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1987 • 823 citations

pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

1987 • 620 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen

1987 • 485 citations

HIV infection is blocked in vitro by recombinant soluble CD4

1988 • 446 citations

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1988 • 425 citations

The CD4 antigen: Physiological ligand and HIV receptor

1988 • 413 citations

Soluble CD4 molecules neutralize human immunodeficiency virus type 1

1988 • 403 citations

Epitopes of the CD4 Antigen and HIV Infection

1986 • 379 citations

Human immunodeficiency virus can productively infect cultured human glial cells.

1987 • 307 citations

Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism.

1988 • 299 citations

Variable and conserved neutralization antigens of human immunodeficiency virus

1986 • 296 citations

Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4

1988 • 294 citations

The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4

1988 • 277 citations

HIV infection does not require endocytosis of its receptor, CD4

1988 • 228 citations

Isolation of transforming DNA: Cloning the hamster aprt gene

1980 • 226 citations

Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: Receptor modulation and differentiation induced by phorbol ester

1987 • 187 citations

Infection of brain-derived cells with the human immunodeficiency virus

1987 • 172 citations

Establishment of a human medulloblastoma cell line

1977 • 161 citations

The human and simian immunodeficiency viruses HIV-1, HIV-2 and SIV interact with similar epitopes on their cellular receptor, the CD4 molecule

1988 • 144 citations

Pseudotypes of human T-cell leukemia virus types 1 and 2: neutralization by patients' sera.

1984 • 139 citations

Susceptibility to infection by the human immunodeficiency virus (HIV) correlates with T4 expression in a parental monocytoid cell line and its subclones

1987 • 130 citations

HIV infection of primate lymphocytes and conservation of the CD4 receptor

1987 • 107 citations

Monoclonal anti-idiotypic antibody mimics the CD4 receptor and binds human immunodeficiency virus.

1987 • 85 citations

Susceptibility of human glial cells to infection with human immunodeficiency virus (HIV)

1987 • 75 citations

Studies on human immunodeficiency virus-induced cytopathic effects: use of human rhabdomyosarcoma (RD) cells

1988 • 17 citations

Characterization of a monoclonal antibody specific for the HIV-1 precursor glycoprotein

1988 • 12 citations