T Cells Expressing Activated LFA-1 Are More Susceptible to Infection with Human Immunodeficiency Virus Type 1 Particles Bearing Host-Encoded ICAM-1

Adhesion receptors of the immune system

1990 • 6,585 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 • 1,194 citations

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5

1996 • 1,181 citations

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

1996 • 1,058 citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

1988 • 967 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

HIV-1 replication is controlled at the level of T cell activation and proviral integration.

1990 • 800 citations

The Reservoir for HIV-1 in Human Peripheral Blood Is a T Cell That Maintains Expression of CD4

1989 • 732 citations

Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins

1987 • 517 citations

Lymphoid organs function as major reservoirs for human immunodeficiency virus.

1991 • 489 citations

The dynamic regulation of integrin adhesiveness

1994 • 456 citations

Evidence for Cell-Surface Association Between Fusin and the CD4-gp120 Complex in Human Cell Lines

1996 • 367 citations

Follicular dendritic cells and human immunodeficiency virus infectivity

1995 • 313 citations

Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity

1997 • 280 citations

Involvement of a Leukocyte Adhesion Receptor (LFA-1) in HIV-Induced Syncytium Formation

1989 • 264 citations

Ins and outs of LFA-1

1995 • 260 citations

Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1.

1995 • 250 citations

A monoclonal antibody (NKI-L16) directed against a unique epitope on the alpha-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions.

1988 • 248 citations

Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization

1991 • 228 citations

Microvesicles Are a Source of Contaminating Cellular Proteins Found in Purified HIV-1 Preparations

1997 • 210 citations

Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses

1994 • 204 citations

HIV requires multiple gp120 molecules for CD4-mediated infection

1990 • 179 citations

Cell Membrane Vesicles Are a Major Contaminant of Gradient-Enriched Human Immunodeficiency Virus Type-1 Preparations

1997 • 149 citations

The presence of host-derived HLA-DR1 on human immunodeficiency virus type 1 increases viral infectivity

1997 • 141 citations

Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization

1997 • 140 citations

Acquisition of host cell-surface-derived molecules by HIV-1

1996 • 139 citations

A novel LFA-1 activation epitope maps to the I domain.

1993 • 136 citations

A Sensitive Reporter Cell Line for HIV-1tatActivity, HIV-1 Inhibitors, and T Cell Activation Effects

1994 • 130 citations

Lymphocyte Locomotion and Migration

2015 • 118 citations

Nonrandom association of cellular antigens with HTLV-III virions

1987 • 113 citations

Human immunodeficiency virus (HIV) infection in CD4+ T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmission.

1991 • 109 citations

Direct identification of class II histocompatibility DR proteins in preparations of human T-cell lymphotropic virus type III

1987 • 107 citations

Host cell-dependent alterations in envelope components of human immunodeficiency virus type 1 virions

1997 • 100 citations

The Amount of Host HLA-DR Proteins Acquired by HIV-1 Is Virus Strain- and Cell Type-Specific

1996 • 98 citations

Unidirectional budding of HIV-1 at the site of cell-to-cell contact is associated with co-polarization of intercellular adhesion molecules and HIV-1 viral matrix protein

1995 • 92 citations

The Acquisition of Host-Derived Major Histocompatibility Complex Class II Glycoproteins by Human Immunodeficiency Virus Type 1 Accelerates the Process of Virus Entry and Infection in Human T-Lymphoid Cells

1997 • 83 citations

HLA Class II on HIV Particles Is Functional in Superantigen Presentation to Human T Cells: Implications for HIV Pathogenesis

1995 • 79 citations

HIV Acquires Functional Adhesion Receptors from Host Cells

1995 • 68 citations

Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1

1995 • 63 citations

HIV Type 1 Grown on Interferon γ-Treated U937 Cells Shows Selective Increase in Virion-Associated Intercellular Adhesion Molecule 1 and HLA-DR and Enhanced Infectivity for CD4-Negative Cells

1995 • 53 citations

The role of lymphoid organs in the immunopathogenesis of HIV infection

1993 • 38 citations

Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.

1990 • 37 citations

The role of lymphoid organs in the immunopathogenesis of HIV infection

1992 • 36 citations

The Acquisition of Host-Derived Major Histocompatibility Complex Class II Glycoproteins by Human Immunodeficiency Virus Type 1 Accelerates the Process of Virus Entry and Infection in Human T-Lymphoid Cells

1997 • 34 citations

Involvement of human leukocyte antigen class I molecules in human immunodeficiency virus infection of CD4-positive cells

1994 • 32 citations

Adhesion Mediated by Intercellular Adhesion Molecule 1 Attenuates the Potency of Antibodies That Block HIV-1 gp160-Dependent Syncytium Formation

1994 • 26 citations

Host cell antigenic profile acquired by HIV-1 is a marker of its cellular origin

1995 • 13 citations