Localization of adenylyl and guanylyl cyclase in rat brain by in situ hybridization: comparison with calmodulin mRNA distribution

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Localization of nitric oxide synthase indicating a neural role for nitric oxide

1990 • 2,996 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Long-Term Depression

1989 • 1,151 citations

Long-term potentiation and NMDA receptors in rat visual cortex

1987 • 953 citations

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

1991 • 875 citations

Adenyl Cyclase

1962 • 853 citations

Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure

1989 • 745 citations

Identification of a Specialized Adenylyl Cyclase That May Mediate Odorant Detection

1990 • 695 citations

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

1985 • 636 citations

PROTEIN KINASES IN THE BRAIN

1985 • 559 citations

Identification of a calcium-binding protein as a calcium-dependent regulator of brain adenylate cyclase.

1975 • 546 citations

N-methyl-D-aspartate receptor antagonist desegregates eye-specific stripes.

1987 • 529 citations

Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action?

1989 • 451 citations

Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin.

1978 • 446 citations

Protein phosphorylation in the brain

1983 • 428 citations

Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches

1990 • 397 citations

Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brain

1988 • 390 citations

Cloning and expression of a widely distributed (type IV) adenylyl cyclase.

1991 • 363 citations

Protein activator of cyclic 3′:5′-nucleotide phosphodiesterase of bovine or rat brain also activates its adenylate cyclase

1975 • 361 citations

Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.

1991 • 286 citations

Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain.

1981 • 279 citations

Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: Expression in areas associated with learning and memory

1991 • 269 citations

Differential expression of three glutamate receptor genes in developing rat brain: an in situ hybridization study.

1991 • 252 citations

Calmodulin Activation of Adenylate Cyclase in Pancreatic Islets

1979 • 234 citations

Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration

1990 • 226 citations

Molecular cloning and expression of cDNAs coding for soluble guanylate cyclase from rat lung.

1990 • 220 citations

Differential regional expression of three natriuretic peptide receptor genes within primate tissues.

1991 • 189 citations

Immunohistochemical localization of guanylate cyclase within neurons of rat brain.

1982 • 186 citations

Mapping second messenger systems in the brain: differential localizations of adenylate cyclase and protein kinase C.

1986 • 181 citations

Long-term potentiation in the hippocampus

1983 • 167 citations

Immunocytochemistry of cGMP in the Cerebellum of the Immature, Adult, and Aged Rat: the Involvement of Nitric Oxide. A Micropharmacological Study

1990 • 159 citations

Dephosphorylation of Neuromodulin by Calcineurin

1989 • 157 citations

Climbing fiber activation and 3′,5′-cyclic guanosine monophosphate (cGMP) content in cortex and deep nuclei of cerebellum

1976 • 156 citations

Calmodulin activates the isolated catalytic unit of brain adenylate cyclase.

1981 • 147 citations

G Proteins: Transducers Of Receptor-Generated Signals

1987 • 143 citations

Molecular cloning of a cDNA coding for 70 kilodalton subunit of soluble guanylate cyclase from rat lung

1988 • 140 citations

Localization of mRNAs encoding the α‐subunits of signal‐transducing G‐proteins within rat brain and among peripheral tissues

1987 • 130 citations

Two different adenylyl cyclases in brain distinguished by monoclonal antibodies

1988 • 126 citations

Immunocytochemical localization of cyclic GMP: Light and electron microscope evidence for involvement of neuroglia

1979 • 112 citations

Enzymatic regulation of the concentration of cyclic GMP in mouse brain

1978 • 106 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 94 citations

Immunological distinction between calmodulin-sensitive and calmodulin-insensitive adenylate cyclases.

1987 • 93 citations

The expanding family of guanylyl cyclases

1991 • 91 citations

Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species.

1987 • 91 citations

Muscarinic cholinergic receptors in rat corpus striatum and regulation of guanosine cyclic 3',5'-monophosphate.

1978 • 86 citations

The Croonian Lecture, 1988 - Inositol lipids and calcium signalling

1988 • 81 citations

Rapid mobility of motile varicosities and inclusions containing alpha- spectrin, actin, and calmodulin in regenerating axons in vitro

1985 • 80 citations

Long-term desensitization of quisqualate-specific glutamate receptors in Purkinje cells investigated with wedge recording from rat cerebellar slices

1989 • 76 citations

Biochemical regulation and physiological significance of cyclic nucleotides in the nervous system.

1977 • 67 citations

In situ hybridization histochemistry and the study of gene expression in the human brain

1990 • 62 citations

Guanylate cyclase activity in various rat brain areas

1977 • 58 citations

The catalytic unit of ram sperm adenylate cyclase can be activated through the guanine nucleotide regulatory component and prostaglandin receptors of human erythrocyte.

1981 • 56 citations

Regional Distribution of Calmodulin Activity in Rat Brain

1985 • 54 citations

Ca²⁺/Calmodulin Distinguishes Between Guanyl‐5′‐yl‐Imidodiphosphate‐and Opiate‐Mediated Inhibition of Rat Striatal Adenylate Cyclase

1987 • 49 citations

Calmodulin stimulation and calcium regulation of smooth muscle adenylate cyclase activity.

1983 • 48 citations

Calmodulin plays a dominant role in determining neurotransmitter regulation of neuronal adenylate cyclase

1988 • 44 citations

Redox modulation of splenic cell soluble guanylate cyclase activity: activation by hydrophilic and hydrophobic oxidants represented by ascorbic and dehydroascorbic acids, fatty acid hydroperoxides, and prostaglandin endoperoxides.

1978 • 40 citations

Calmodulin is tightly associated with synaptic vesicles independent of calcium.

1984 • 39 citations

Differential Regional Expression of Three Natriuretic Peptide Receptor Genes within Primate Tissues

1991 • 38 citations

Differences between high-affinity forskolin binding sites in dopamine-rich and other regions of rat brain.

1988 • 36 citations

Different chromosomal localization of two adenylyl cyclase genes expressed in human brain

1992 • 36 citations

Nerve cells and nervous systems: an introduction to neuroscience

1991 • 35 citations

Regulation of Calmodulin-sensitive Adenylate Cyclase by the Stimulatory G-protein, Gs

1989 • 32 citations

Calmodulin activates adenylate cyclase from rabbit heart plasma membranes

1984 • 26 citations

Inositol lipids and calcium signalling

1990 • 24 citations

Calmodulin stimulation of the rat cerebral cortical adenylate cyclase is required for the detection of guanine nucleotide- or hormone-mediated inhibition.

1987 • 18 citations

Trypsin solubilization of rat liver membrane-bound guanylate cyclase results in a form kinetically distinct from the cytosolic enzyme.

1981 • 17 citations

General characteristics, localization, and adaptative responsiveness of neurotransmitter-sensitive adenylate cyclases in the central nervous system.

1981 • 10 citations

Acute and chronic effects of climbing fiber lesions on cerebellar cyclic guanosine monophosphate

1987 • 6 citations

Nerve Cells and Nervous Systems: An introduction to neuroscience

1992 • 2 citations