The catalytic unit of ram sperm adenylate cyclase can be activated through the guanine nucleotide regulatory component and prostaglandin receptors of human erythrocyte.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

[16] Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes

1974 • 1,028 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

Resolution of some components of adenylate cyclase necessary for catalytic activity.

1977 • 283 citations

Selection of a Variant Lymphoma Cell Deficient in Adenylate Cyclase

1975 • 276 citations

Development of a Mn-2+-sensitive, "soluble" adenylate cyclase in rat testis.

1975 • 190 citations

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.

1977 • 173 citations

Resolution, reconstitution and kinetics of the primary action of a hormone receptor

1980 • 149 citations

Unique uncoupling of the frog erythrocyte adenylate cyclase system by manganese. Loss of hormone and guanine nucleotide-sensitive enzyme activities without loss of nucleotide-sensitive, high affinity agonist binding.

1979 • 122 citations

[6] Separation and purification of cyclic nucleotides by alumina column chromatography

1974 • 114 citations

Adenylate cyclase assembled in vitro: cholera toxin substrates determine different patterns of regulation by isoproterenol and guanosine 5'-triphosphate.

1979 • 114 citations

A regulatory component of adenylate cyclase from human erythrocyte membranes.

1980 • 109 citations

Proteolytic activation of rat liver adenylate cyclase by a contaminant of crude collagenase from Clostridium histolyticum.

1977 • 102 citations

Reconstitution of cholera toxin-activated adenylate cyclase.

1978 • 98 citations

Physical and functional properties of adenylate cyclase from mature rat testis

1978 • 94 citations

Transient and steady state kinetics of the interaction of guanyl nucleotides with the adenylyl cyclase system from rat liver plasma membranes. Interpretation in terms of a simple two-state model.

1980 • 92 citations

Characteristics of the guanine nucleotide regulatory component of adenylate cyclase in human erythrocyte membranes

1980 • 77 citations

Enzymes of cyclic nucleotide metabolism in invertebrate and vertebrate sperm

1976 • 75 citations

Mn2+-sensitive, soluble adenylate cyclase in rat testis Differentiation from other testicular nucleotide cyclases

1977 • 63 citations

Bull sperm adenylate cyclase: Localization and partial characterization

1976 • 51 citations

Demonstration of adenylate cyclase activity in human red blood cell ghosts

1976 • 49 citations

Adenylate cyclase activity of bovine spermatozoa during maturation in the epididymis and the activation of sperm particulate adenylate cyclase by GTP and polyamines

1980 • 45 citations

On the mode of action of catecholamines on the turkey erythrocyte adenylyl cyclase. Evaluation of basic activity states after removal of endogenous GDP and interpretation of nucleotide regulation and hormone activation in terms of a two-state model.

1980 • 30 citations

Effects of cholera toxin and 5′-guanylylimidodiphosphate on human spermatozoal adenylate cyclase activity

1979 • 29 citations

Naturally soluble component(s) that confer(s) guanine nucleotide and fluoride sensitivity to adenylate cyclase.

1980 • 29 citations

A regulatory component of adenylate cyclase is located on the inner surface of human erythrocyte membranes

1979 • 25 citations

Proteolysis activates adenylate cyclase in rat liver and AC⁻ lymphoma cell independently of the guanine nucleotide regulatory site

1980 • 24 citations

Hybridization of adenylate cyclase components by membrane fusion and the effect of selective digestion by trypsin.

1980 • 24 citations

Change in the cation dependence of rat liver adenylate cyclase after proteolytic activation

1979 • 14 citations

Measurement of adenylate cyclase activity in ram spermatozoa

1976 • 13 citations

A probe for the organization of the β‐adrenergic receptor‐regulated adenylate cyclase system in turkey erythrocyte membranes by the use of a complementation assay

1980 • 8 citations