A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus.

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids.

1981 • 544 citations

High frequency of natural autoantibodies in normal newborn mice.

1985 • 387 citations

Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity.

1984 • 344 citations

QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES

1972 • 291 citations

Origins of anti-DNA autoantibodies.

1985 • 289 citations

Idiotypic cross-reactions of monoclonal human lupus autoantibodies.

1983 • 285 citations

Production of autoantibodies by human-human hybridomas.

1982 • 228 citations

Somatic evolution of variable region structures during an immune response.

1986 • 211 citations

Antigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNA.

1981 • 171 citations

Lymphocytes capable of making monoclonal autoantibodies that react with multiple organs are a common feature of the normal B cell repertoire.

1984 • 171 citations

Binding of cytoskeletal proteins by monoclonal anti-DNA lupus autoantibodies

1984 • 171 citations

The genetic basis of antibody production: A single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse

1983 • 151 citations

Human Monoclonal Autoantibodies That React with Multiple Endocrine Organs

1983 • 145 citations

Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies.

1985 • 139 citations

Influence of Clonal Selection on the Expression of Immunoglobulin Variable Region Genes

1984 • 120 citations

A monoclonal anti-DNA antibody also binds to cell-surface protein(s).

1984 • 118 citations

Anti-oxazolone hybridomas and the structure of the oxazolone idiotype.

1983 • 114 citations

Lupus prone (SWR x NZB)F1 mice produce potentially nephritogenic autoantibodies inherited from the normal SWR parent.

1985 • 107 citations

Mouse Myelomas producing Precipitating Antibody to Nucleic Acid Bases and/or Nitrophenyl Derivatives

1968 • 102 citations

Expression and rearrangement of homologous immunoglobulin VH genes in two mouse strains.

1984 • 84 citations

Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera

1983 • 83 citations

Hybrids from normal, germ free, nude and neonatal mice produce monoclonal autoantibodies to eight different intracellular structures.

1985 • 80 citations

Homology of the NH2-terminal amino acid sequences of the heavy and light chains of human monoclonal lupus autoantibodies containing the dominant 16/6 idiotype.

1985 • 79 citations

Binding of monoclonal anti-native DNA autoantibodies to DNA of varying size and conformation

1985 • 78 citations

Structural diversity among anti-p-azophenylarsonate monoclonal antibodies from A/J mice: Comparison of Id− and Id+ sequences

1981 • 65 citations

Expression of a VHCκ chimaeric protein in mouse myeloma cells

1984 • 57 citations

Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA sequences in whole cell lysates.

1984 • 54 citations

Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity.

1985 • 51 citations

Presence of natural autoantibodies in hyperimmunized mice.

1985 • 48 citations

Autoantibodies to intracellular proteins

1986 • 48 citations

Idiotype connectance in the immune system. I. Expression of a cross-reactive idiotype on induced anti-p-azophenylarsonate antibodies and on endogenous antibodies not specific for arsonate.

1983 • 45 citations

Two structurally distinct and independently regulated idiotypic families associated with the A/J response to azophenylarsonate

1981 • 44 citations

γM RHEUMATOID FACTORS REACTING WITH NITROPHENYL GROUPS AND DENATURED DEOXYRIBONUCLEIC ACID

1969 • 40 citations

Base specificity and idiotypy of anti-DNA autoantibodies reactive with synthetic nucleic acids.

1985 • 38 citations

Murine polyspecific antibodies. I. Monoclonal and serum anti-DNA antibodies cross-reactive with 2,4,6-trinitrophenyl derivatives.

1985 • 30 citations

T-cell hybridoma specific for a cytochrome c peptide: specific antigen binding and interleukin 2 production.

1983 • 29 citations

A human myeloma protein with specificity against dinitrophenyl and nucleic acid derivatives

1972 • 23 citations

Structural Correlates of Idiotypy in the Arsonate System^a

1983 • 22 citations

Amino acid sequence of the Fv region of a human monoclonal IgM (protein WEA) with antibody activity against 3,4-pyruvylated galactose in Klebsiella polysaccharides K30 and K33.

1983 • 21 citations

The interaction of mouse myeloma immunoglobulin S15 with negatively charged polysaccharide antigens

1982 • 9 citations

Autoantibodies and nuclear antigens

1985 • 8 citations