Structural Correlates of Idiotypy in the Arsonate System^a

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a γ2a variable region

1981 • 677 citations

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

1981 • 509 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.

1982 • 411 citations

Analysis of the repertoire of anti‐NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

1978 • 316 citations

QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES

1972 • 291 citations

Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangments in heavy chain V-region gene segments

1980 • 272 citations

Similar Idiotypic Specificities in Immunoglobulin Fractions with Different Antibody Functions or Even without Detectable Antibody Function

1971 • 228 citations

Idiotypic regulation of the immune system by the induction of antibodies against anti-idiotypic antibodies.

1977 • 211 citations

The genetic basis of antibody production: A single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse

1983 • 151 citations

IUPAC-IUB Commission on Biochemical Nomenclature A One-Letter Notation for Amino Acid Sequences1–3

1968 • 140 citations

Hybridoma proteins expressing the predominant idiotype of the antiazophenylarsonate response of A/J mice.

1980 • 129 citations

Single amino acid substitution altering antigen-binding specificity.

1982 • 112 citations

Absolute frequencies of lipopolysaccharide-reactive B cells producing A5A idiotype in unprimed, streptococcal A carbohydrate-primed, anti-A5A idiotype-sensitized and anti-A5A idiotype-suppressed A/J mice.

1977 • 104 citations

The genetic basis of antibody production: The dominant anti‐arsonate idiotype response of the strain a mouse

1982 • 100 citations

Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera

1983 • 83 citations

Structural studies on induced antibodies with defined idiotypic specificities. IX. Framework differences in the heavy- and light-chain-variable regions of monoclonal anti-p-azophenylarsonate antibodies from A/J mice differing with respect to a cross-reactive idiotype.

1980 • 73 citations

The strain A anti‐p‐azophenylarsonate major crossreactive idiotypic family includes members with no reactivity toward p‐azophenylarsonate

1981 • 67 citations

Structural diversity among anti-p-azophenylarsonate monoclonal antibodies from A/J mice: Comparison of Id− and Id+ sequences

1981 • 65 citations

Somatic Mutation in Genes for the Variable Portion of the Immunoglobulin Heavy Chain

1982 • 60 citations

Structural Studies on Induced Antibodies with Defined Idiotypic Specificities

1975 • 57 citations

Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype.

1981 • 56 citations

Idiotypic analysis of monoclonal antibodies to poly(Glu60Ala30Tyr10).

1979 • 45 citations

Two structurally distinct and independently regulated idiotypic families associated with the A/J response to azophenylarsonate

1981 • 44 citations

VH families in the antibody response to p-azophenylarsonate: correlation between serology and amino acid sequence.

1982 • 44 citations

Structural studies on induced antibodies with defined idiotypic specificities—VIII.

1979 • 40 citations

Monoclonal ant-idiotypic antibodies reactive with a highly conserved determinant on A/J serum anti-para-azophenylarsonate antibodies.

1981 • 35 citations

Unique determinants associated with hybridoma proteins expressing a cross-reactive idiotype: frequency among individual immune sera.

1980 • 30 citations

Immunoglobulin idiotype and anti-anti-idiotype utilize the same variable region genes irrespective of antigen specificity.

1983 • 30 citations

Relationship of idiotypes of the anti-p-azophenylarsonate antibodies of A/J and BALB/c mice.

1981 • 26 citations

An intrastrain cross-reactive idiotype associated with anti-p-azophenylarsonate antibodies of BALB/c mice.

1981 • 24 citations

Induction and characterization of isogeneic anti‐idiotypic antibodies to BALB/c myeloma S117: lack of reactivity with major idiotypic determinants

1979 • 22 citations

Structural Studies on Induced Antibodies with Defined Idiotypic Specificities

1979 • 20 citations

Fine specificity of idiotope suppression in the A/J anti-azophenylarsonate response.

1983 • 19 citations

Structural Studies on Induced Antibodies with Defined Idiotypic Specificities

1977 • 16 citations