Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity.

Somatic generation of antibody diversity

1983 • 3,275 citations

Variability in the Lambda Light Chain Sequences of Mouse Antibody

1970 • 554 citations

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin.

1984 • 545 citations

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids.

1981 • 544 citations

Etiopathogenesis of Murine SLE¹

1981 • 517 citations

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

1981 • 509 citations

Gene conversion: Some implications for immunoglobulin genes

1981 • 496 citations

A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody

1981 • 470 citations

Structural Basis of Antibody Function

1983 • 371 citations

Antibody diversity: Somatic hypermutation of rearranged VH genes

1981 • 334 citations

Anti-phosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae.

1982 • 303 citations

Idiotypic cross-reactions of monoclonal human lupus autoantibodies.

1983 • 285 citations

Antigen-Binding Myeloma Proteins of Mice

1978 • 272 citations

Molecular Forms and Subunit Composition of a Cyclic Adenosine 3′,5′-Monophosphate-dependent Protein Kinase Purified from Bovine Heart Muscle

1972 • 255 citations

Use of Monoclonal Anti-mouse Immunoglobulin to Detect Mouse Antibodies

1981 • 252 citations

Responsiveness of autoimmune and normal mice to nucleic acid antigens.

1984 • 223 citations

Immunologic relation of streptococcal and tissue antigens. I. Properties of an antigen in certain strains of Group A streptococci exhibiting an immunologic cross-reaction with human heart tissue

2001 • 208 citations

A millipore filter assay for antibodies to native dna in sera of patients with systemic lupus erythematosus

1973 • 169 citations

Structural basis for the specificity of phosphorylcholine-binding immunoglobulins

1976 • 125 citations

Enzyme immunoassay for antibodies to native DNA

1983 • 118 citations

ANTIGEN-BINDING MYELOMA PROTEINS IN MICE

1971 • 115 citations

Single amino acid substitution altering antigen-binding specificity.

1982 • 112 citations

Recombination between antibody heavy chain variable-region genes: evidence for gene conversion.

1983 • 104 citations

Monoclonal antibodies to DNA and RNA from NZB/NZW F1 mice: antigenic specificities and NH2 terminal amino acid sequences.

1984 • 98 citations

Antibodies cross-reactive with DNA and cardiolipin in patients with systemic lupus erythematosus.

1982 • 91 citations

Affinity analysis of idiotype-positive and idiotype-negative Ars-binding hybridoma proteins and Ars-immune sera

1983 • 83 citations

Antigen-binding mutants of mouse myeloma cells.

1977 • 82 citations

The Response to Phosphorylcholine Dissecting an Immune Response

1975 • 81 citations

Isotypes of spontaneous and mitogen-induced autoantibodies in SLE-prone mice.

1984 • 79 citations

An improved ELISA for anti-native DNA by elimination of interference by anti-histone antibodies

1983 • 78 citations

Restriction in IgM expression. IV. Affinity analysis of monoclonal anti-phosphorylcholine antibodies.

1983 • 74 citations

Monoclonal Antibodies Reveal the Structural Basis of Antibody Diversity

1983 • 70 citations

Nucleic acid and protein sequences of phosphocholine-binding light chains.

1981 • 45 citations

Attempts to locate residues in complementarity-determining regions of antibody combining sites that make contact with antigen.

1976 • 42 citations

Evidence for gene conversion among immunoglobulin heavy chain variable region genes.

1984 • 31 citations

The response to phosphorylcholine: dissecting an immune response.

1975 • 21 citations