α3β1 integrin induced suppression of the Caco-2 epithelial cell IL-1 signaling pathway leading to NF-κB activation

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

Interleukin-6 family of cytokines and gp130

1995 • 1,314 citations

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

1995 • 1,205 citations

Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation

1999 • 855 citations

Nuclear factor κB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

1998 • 696 citations

Signal Transduction by Cell Adhesion Receptors and the Cytoskeleton: Functions of Integrins, Cadherins, Selectins, and Immunoglobulin-Superfamily Members

2002 • 597 citations

Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants

1998 • 573 citations

Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation.

1995 • 400 citations

The IκB/NF-κB system: a key determinant of mucosal inflammation and protection

2000 • 377 citations

NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria.

1999 • 334 citations

Bridging the Gap: Composition, Regulation, and Physiological Function of the IκB Kinase Complex

1999 • 324 citations

Cytokine induction of monocyte chemoattractant protein‐1 gene expression in human endothelial cells depends on the cooperative action of NF‐χB and AP‐1

1997 • 318 citations

Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa

1995 • 293 citations

NF-κB Is a Central Regulator of the Intestinal Epithelial Cell Innate Immune Response Induced by Infection with Enteroinvasive Bacteria

1999 • 272 citations

The α3 laminin subunit, α6β4 and α3β1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin

1999 • 255 citations

Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion

2000 • 247 citations

The inner lives of focal adhesions

2002 • 206 citations

Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells.

1997 • 183 citations

Functions of α3β1 integrin

2000 • 179 citations

A Cell Signal Pathway Involving Laminin-5, α3β1 Integrin, and Mitogen-activated Protein Kinase Can Regulate Epithelial Cell Proliferation

1999 • 155 citations

α5β1 Integrin Activates an NF-κB-Dependent Program of Gene Expression Important for Angiogenesis and Inflammation

2002 • 123 citations

Integrins and human intestinal cell functions

1999 • 118 citations

Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6.

1993 • 110 citations

Intestinal epithelial restitution. Involvement of specific laminin isoforms and integrin laminin receptors in wound closure of a transformed model epithelium.

1997 • 95 citations

Fibronectin attachment activates the NF-kappa B p50/p65 heterodimer in fibroblasts and smooth muscle cells.

1994 • 87 citations

Ligation of Integrin α3β1 by Laminin 5 at the Wound Edge Activates Rho-dependent Adhesion of Leading Keratinocytes on Collagen

2001 • 68 citations

Human colonic cancer cells synthesize and adhere to laminin-5. Their adhesion to laminin-5 involves multiple receptors among which is integrin α2β1

1998 • 68 citations

Phosphatidylinositol 3-kinase mediates integrin-dependent NF-κB and MAPK activation through separate signaling pathways

2001 • 57 citations

Integrins and human intestinal cell functions

1999 • 42 citations

Mechanisms of colon cancer binding to substratum and cells

1996 • 32 citations

Regulation of epithelial cell cytokine responses by the α3β1 integrin

2003 • 23 citations

Biotinylated probes in the electrophoretic mobility shift assay to examine specific dsDNA, ssDNA or RNA–protein interactions

1995 • 23 citations

Deleted Work

1955 • 0 citations