Hypoxia-stimulated expression of angiogenic growth factors in cervical cancer cells and cervical cancer-derived fibroblasts

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

1989 • 3,308 citations

Tumor Induction of VEGF Promoter Activity in Stromal Cells

1998 • 964 citations

Oxygenation predicts radiation response and survival in patients with cervix cancer

1998 • 604 citations

Macrophage responses to hypoxia: relevance to disease mechanisms

1999 • 391 citations

Human Endothelium as a Source of Multifunctional Cytokines: Molecular Regulation and Possible Role in Human Disease

1999 • 333 citations

Production of Vascular Endothelial Growth Factor by Murine Macrophages

1998 • 304 citations

Angiogenesis and Metastasis

2002 • 294 citations

104 candidate genes for the hypoxic tumor phenotype

1999 • 283 citations

Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.

1998 • 244 citations

Hypoxia Upregulates the Synthesis of TGF-β1 by Human Dermal Fibroblasts

1991 • 230 citations

Expression of vascular endothelial growth factor in synovial fibroblasts is induced by hypoxia and interleukin 1beta.

1997 • 226 citations

Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix

1999 • 213 citations

Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor β-1

1998 • 193 citations

Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression.

1994 • 185 citations

Expression of vascular endothelial growth factor (VEGF) and its two receptors (VEGF‐R1‐Flt1 and VEGF‐R2‐Flk1/KDR) in non‐small cell lung carcinomas (NSCLCs): correlation with angiogenesis and survival

1999 • 177 citations

Hypoxia-induced up-regulation of angiogenin in human malignant melanoma.

1999 • 158 citations

Pericellular PO2 and O2 consumption in monolayer cell cultures

1995 • 154 citations

Fibroblast Response to Hypoxia: The Relationship between Angiogenesis and Matrix Regulation

1999 • 150 citations

Tumoral vascularity as a prognostic factor in cancer.

1996 • 146 citations

Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia

1997 • 139 citations

3-D Coculture of Hepatic Sinusoidal Cells with Primary Hepatocytes—Design of an Organotypical Model

1996 • 115 citations

Cell inactivation and cell cycle inhibition as induced by extreme hypoxia: the possible role of cell cycle arrest as a protection against hypoxia‐induced lethal damage

1991 • 112 citations

Angiogenesis in Malignancies of the Female Genital Tract

1999 • 103 citations

Treatment outcome in advanced squamous cell carcinoma of the uterine cervix: relationships to pretreatment tumor oxygenation and vascularization

2000 • 99 citations

Adaptive Responses of the Endothelium to Stress

2000 • 82 citations

Expression and regulation of vascular endothelial growth factor in choroidal fibroblasts

1995 • 80 citations

Different Angiogenic Pathways in Human Cervical Cancers

1998 • 64 citations

Expression of vascular endothelial growth factor (VEGF) and its mRNA in uterine cervical cancers

1999 • 62 citations

A quantitative analysis of the reduction in oxygen levels required to induce up-regulation of vascular endothelial growth factor (VEGF) mRNA in cervical cancer cell lines

1999 • 47 citations

Secretion rates and levels of vascular endothelial growth factor in clone A or HCT‐8 human colon tumour cells as a function of oxygen concentration

1995 • 36 citations

Immunohistochemical expression of growth factors in subacute thyroiditis and their effects on thyroid folliculogenesis and angiogenesis in collagen gel matrix culture

1999 • 34 citations

Quantitative RT-PCR Assay Detecting the Transcriptional Induction of Vascular Endothelial Growth Factor Under Hypoxia

1994 • 33 citations

Hypoxia-Induced Release of Peptide Growth Factors from Neonatal Porcine Pulmonary Artery Smooth Muscle Cells

1999 • 24 citations