Differential effects of repeated administration of novel antipsychotic drugs on the activity of midbrain dopamine neurons in the rat

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

A Canadian Multicenter Placebo-Controlled Study of Fixed Doses of Risperidone and Haloperidol in the Treatment of Chronic Schizophrenic Patients

1993 • 884 citations

Imaging Dopamine Receptors in the Human Brain by Positron Tomography

1983 • 743 citations

Differential Effects of Classical and Atypical Antipsychotic Drugs on A9 and A10 Dopamine Neurons

1983 • 589 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.

1988 • 429 citations

Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors

1993 • 334 citations

Seroquel: biochemical profile of a potential atypical antipsychotic

1993 • 271 citations

Risperidone: clinical safety and efficacy in schizophrenia.

1992 • 208 citations

Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons

1985 • 196 citations

Survey on the pharmacodynamics of the new antipsychotic risperidone

1994 • 195 citations

Clonidine modulates dopamine cell firing in rat ventral tegmental area

1989 • 126 citations

Seroquel: electrophysiological profile of a potential atypical antipsychotic

1993 • 117 citations

Neurochemical and in vivo pharmacological profile of sertindole, a limbic-selective neuroleptic compound

1991 • 113 citations

Seroquel: behavioral effects in conventional and novel tests for atypical antipsychotic drug

1993 • 103 citations

Double-blind Comparison of Risperidone and Haloperidol in Schizophrenic and Schizoaffective Psychoses

1993 • 99 citations

Dose dependent occupancy of central dopamine D2 receptors by the novel neuroleptic CP-88,059-01: a study using positron emission tomography and11C-raclopride

1993 • 98 citations

Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurones in rats: Acute and repeated treatment

1992 • 86 citations

Effects of amperozide in schizophrenia

1991 • 59 citations

Sertindole, a new neuroleptic with extreme selectivity on A10 versus A9 dopamine neurones in the rat

1990 • 59 citations

Effects of amperozide, a putative antipsychotic drug, on rat midbrain dopamine neurons recorded in vivo

1990 • 53 citations

P-4-71 Efficacy and safety of sertindole in two double-blind, placebo-controlled trials of schizophrenic patients

1995 • 46 citations

Phencyclidine activates rat A10 dopamine neurons but reduces burst activity and causes regularization of firing

1990 • 42 citations

Amperozide and emotional behaviour

1990 • 42 citations

Clozapine: An atypical neuroleptic

1990 • 41 citations

Effect of amperozide on rat cortical 5-HT2 and striatal and limbic dopamine D2 receptor occupancy: Implications for antipsychotic action

1992 • 34 citations

The 5‐HT₂ antagonist ritanserin blocks the effect of pre‐frontal cortex inactivation on rat A10 dopamine neurons in vivo

1989 • 29 citations

Failure of chronic haloperidol to induce depolarization inactivation of dopamine neurons in unanesthetized rats

1994 • 23 citations

Comparison of the effect of substituted benzamides on midbrain dopamine neurones after treatment of rats for 21 days

1993 • 8 citations

Olanzapine, a novel atypical antipsychotic, has electrophysiological effects on A9 and A10 dopamine cells similar to clozapine

1995 • 4 citations