Regulation of gonadotropin-releasing hormone (GnRH) gene expression in hypothalamic neuronal cells

Immortalization of hypothalamic GnRH by genetically targeted tumorigenesis

1990 • 959 citations

A Deletion Truncating the Gonadotropin-Releasing Hormone Gene Is Responsible for Hypogonadism in the hpg Mouse

1986 • 533 citations

Characterization of cDNA for precursor of human luteinizing hormone releasing hormone

1984 • 444 citations

Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat.

1986 • 353 citations

Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons.

1992 • 281 citations

A DNA cassette containing a trimerized SV40 polyadenylation signal which efficiently blocks spurious plasmid-initiated transcription.

1989 • 215 citations

Migratory arrest of gonadotropin-releasing hormone neurons in transgenic mice.

1991 • 214 citations

Calcium signaling and episodic secretion of gonadotropin-releasing hormone in hypothalamic neurons.

1992 • 204 citations

Two Mammalian Genes Transcribed from Opposite Strands of the Same DNA Locus

1987 • 195 citations

Isolation and Characterization of the Human Gonadotropin-Releasing Hormone Gene in the Hypothalamus and Placenta

1990 • 120 citations

Inhibition of gonadotropin hormone-releasing hormonerelease by prolactin from GT1 neuronal cell lines through prolactinreceptors.

1994 • 117 citations

Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene.

1991 • 106 citations

Glucocorticoid receptor-mediated repression of gonadotropin-releasing hormone promoter activity in GT1 hypothalamic cell lines.

1994 • 102 citations

Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons.

1993 • 101 citations

The Rat Gonadotropin-Releasing Hormone: SH Locus: Structure and Hypothalamic Expression

1989 • 101 citations

N-methyl-D-aspartate (NMDA) receptors mediate the release of gonadotropin-releasing hormone (GnRH) by NMDA in a hypothalamic GnRH neuronal cell line (GT1-1).

1994 • 86 citations

Structure of the rat gonadotropin releasing hormone (rGnRH) gene promoter and functional analysis in hypothalamic cells

1992 • 77 citations

The complete nucleotide sequence of the human gonadotropin-releasing hormone gene

1989 • 64 citations

Immortalized hypothalamic GT1-7 neurons express functional gamma-aminobutyric acid type A receptors.

1992 • 59 citations

Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression.

1992 • 57 citations

Transmembrane Signals Mediating Neural Peptide Secretion: Role of Protein Kinase C Activators and Arachidonic Acid Metabolites in Luteinizing Hormone-Releasing Hormone Secretion

1986 • 55 citations

Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.

1986 • 52 citations

Differential expression of gamma-aminobutyric acid receptors in immortalized luteinizing hormone-releasing hormone neurons.

1993 • 49 citations

Processing of gonadotropin-releasing hormone gene transcripts in the rat brain.

1994 • 46 citations

Estrogen negatively regulates rat gonadotropin releasing hormone (rGnRH) promoter activity in transfected placental cells

1992 • 43 citations

Evidence for transcriptional inhibition of GnRH gene expression by phorbol ester at a proximal promoter region

1994 • 37 citations

Diacylglycerol and phorbol esters enhance LHRH and prostaglandin E2 secretion from median eminence nerve terminals in vitro

1985 • 23 citations

Transmembrane Signals and Intracellular Messengers Mediating LHRH and LH Secretion

1987 • 21 citations

Deleted Work

1955 • 0 citations