Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells

1988 • 1,246 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

Estrogen Binding, Receptor mRNA, and Biologic Response in Osteoblast-Like Osteosarcoma Cells

1988 • 836 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode.

1989 • 704 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neurones

1983 • 526 citations

Pituitary Stalk Portal Blood Collection in Rhesus Monkeys: Evidence for Pulsatile Release of Gonadotropin-Releasing Hormone (GnRH)

1976 • 482 citations

Pulsatile Gonadotropin Secretion during the Human Menstrual Cycle: Evidence for Altered Frequency of Gonadotropin-Releasing Hormone Secretion*

1984 • 261 citations

Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene.

1987 • 231 citations

Gonadotropin-Releasing Hormone: Role of Pulsatile Secretion in the Regulation of Reproduction

1986 • 218 citations

Thyroid hormones regulate levels of thyrotropin-releasing-hormone mRNA in the paraventricular nucleus.

1987 • 179 citations

A Single Domain of the Estrogen Receptor Confers Deoxyribonucleic Acid Binding and Transcriptional Activation of the Rat Prolactin Gene

1988 • 173 citations

Relationship of nuclear estrogen receptor levels to induction of ovalbumin and conalbumin mRNA in chick oviduct.

1977 • 164 citations

The Mammalian GnRH Gene and Its Pivotal Role in Reproduction

1987 • 162 citations

Isolation and Characterization of the Human Gonadotropin-Releasing Hormone Gene in the Hypothalamus and Placenta

1990 • 120 citations

Thyroid Hormone Inhibition of Human Thyrotropin β-Subunit Gene Expression is Mediated by a Cis-acting Element Located in the First Exon

1989 • 119 citations

In SituHybridization Histochemistry for Messenger Ribonucleic Acid (mRNA) Encoding Gonadotropin-Releasing Hormone (GnRH): Effect of Estrogen on Cellular Levels of GnRH mRNA in Female Rat Brain

1988 • 113 citations

Regulation of Pro-Gonadotropin-Releasing Hormone Gene Expression by Sex Steroids in The Brain of Male and Female Rats

1989 • 103 citations

Gonadotropin-Releasing Hormone Gene Expression during the Rat Estrous Cycle: Effects of Pentobarbital and Ovarian Steroids*

1990 • 94 citations

Estradiol stimulates preoptic area-anterior hypothalamic proGnRH-GAP gene expression in ovariectomized rats

1989 • 94 citations

An upstream region of the rat luteinizing hormone β gene binds estrogen receptor and confers estrogen responsiveness

1989 • 81 citations

Further Evidence that Most Luteinizing Hormone‐Releasing Hormone Neurons are not Directly Estrogen‐Responsive: Simultaneous Localization of Luteinizing Hormone‐Releasing Hormone and Estrogen Receptor Immunoreactivity in the Guinea‐Pig Brain

1992 • 81 citations

LHRH messenger RNA in neurons in the intact and castrate male rat forebrain, studied by in situ hybridization

1987 • 72 citations

Differential Effects of Estrogen on Luteinizing Hormone-Releasing Hormone Gene Expression in Slice Explant Cultures Prepared from Specific Rat Forebrain Regions

1989 • 65 citations

Effect of Castration and Steroid Replacement on Immunoreactive Gonadotropin-Releasing Hormone in the Hypothalamus and Preoptic Area*

1980 • 65 citations

In situ hybridization for LHRH mRNA following estrogen treatment

1989 • 60 citations

Identification of an Estrogen-Responsive Element from the 5′-Flanking Region of the Rat Prolactin Gene

1987 • 59 citations

Steroid Hormones Modulate the Release of Immunoreactive Gonadotropin-Releasing Hormone from Cultured Human Placental Cells*

1990 • 57 citations

Gene expression in hypothalamic neurons: Luteinizing hormone releasing hormone

1986 • 54 citations

Administration of Gonadal Steroids to the Castrated Male Rat Prevents a Decrease in the Release of Gonadotropin-Releasing Hormone from the Incubated Hypothalamus

1979 • 41 citations

Evidence of Estrogen Receptors in Normal Human Osteoblast-Like Cells

1989 • 16 citations

Selective photochemical treatment of oestrogen receptor in a Xenopus liver extract destroys hormone binding and transcriptional activation but not DNA binding.

1990 • 8 citations