Phorbol ester activation of the protein kinase C pathway inhibits gonadotropin-releasing hormone gene expression.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

1990 • 1,061 citations

Immortalization of hypothalamic GnRH by genetically targeted tumorigenesis

1990 • 959 citations

Regulation of neurotransmitter receptor desensitization by protein phosphorylation

1990 • 439 citations

Glutamic Acid Decarboxylase-Containing Axons Synapse on LHRH Neurons in the Rat Medial Preoptic Area

1985 • 274 citations

Luteinizing hormone-releasing hormone neurons express Fos protein during the proestrous surge of luteinizing hormone.

1990 • 268 citations

Two Mammalian Genes Transcribed from Opposite Strands of the Same DNA Locus

1987 • 195 citations

Luteinizing Hormone-Releasing Hormone Neurons Express c-fosAntigen after Steroid Activation*

1990 • 194 citations

Immunocytochemical evidence for direct synaptic connections between corticotrophin-releasing factor (CRF) and gonadotrophin-releasing hormone (GnRH)- containing neurons in the preoptic area of the rat

1988 • 191 citations

The Mammalian GnRH Gene and Its Pivotal Role in Reproduction

1987 • 162 citations

Demonstration of serotoninergic axons terminating on luteinizing hormone-releasing hormone neurons in the preoptic area of the rat using a combination of immunocytochemistry and high resolution autoradiography

1985 • 129 citations

Role of primary response genes in generating cellular responses to growth factors

1992 • 124 citations

Immunocytochemical and physiological evidence of a synapse between dopamine- and Luteinizing Hormone Releasing Hormone-containing neurons in the ewe median eminence.

1989 • 118 citations

Further Studies on the Radioimmunoassay of Gonadotropin-Releasing Hormone: Effect of Radioiodination, Antiserum and Unextracted Serum on Levels of Immunoreactivity in Serum¹

1977 • 111 citations

The Rat Gonadotropin-Releasing Hormone: SH Locus: Structure and Hypothalamic Expression

1989 • 101 citations

Differences in phorbol-ester-induced down-regulation of protein kinase C between cell lines

1989 • 93 citations

Gonadotropin-Releasing Hormone-Dependent Regulation of Gonadotropin Subunit Messenger Ribonucleic Acid Levels in the Rat*

1989 • 80 citations

Structure of the rat gonadotropin releasing hormone (rGnRH) gene promoter and functional analysis in hypothalamic cells

1992 • 77 citations

Secretion of Corticotropin-Releasing Factor from Cultured Rat Hypothalamic Cells: Effects of Catecholamines*

1989 • 76 citations

GNRH Interaction with Anterior Pituitary. I. Determination of the Affinity and Number of Receptors for GNRH in Ovine Anterior Pituitary1

1979 • 71 citations

Androgen Selectively Stimulates Follicle-Stimulating Hormone-β mRNA Levels after Gonadotropin-Releasing Hormone Antagonist Administration1

1990 • 68 citations

Second Messengers Involved in the Regulation of Corticotropin-Releasing Hormone mRNA and Peptide in Cultured Rat Fetal Hypothalamic Primary Cultures

1990 • 66 citations

Phorbol ester induces both gene expression and phosphorylation of the plasma membrane Ca2+ pump

1991 • 56 citations

Potential sites of interaction between catecholamines and LHRH in the sheep brain

1988 • 52 citations

Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.

1986 • 52 citations

Immunohistochemical Studies on the Roles of Substance P in the Rat Hypothalamus: Possible Implication in the Hypothalamic-Hypophysial-Gonadal Axis

1987 • 32 citations

Catecholamine innervation of LH-RH neurons: a developmental study

1986 • 32 citations

Studies and prospectives of the protein kinase C family for cellular regulation.

1989 • 24 citations

Diacylglycerol and phorbol esters enhance LHRH and prostaglandin E2 secretion from median eminence nerve terminals in vitro

1985 • 23 citations

Signal Transduction Systems in Growth Hormone-Releasing Hormone and Somatostatin Release from Perifused Rat Hypothalamic Fragments^*

1991 • 11 citations

Transmembrane Signals and Neural Peptide Release: Role of Protein Kinase C Activators and Arachidonic Acid

1987 • 4 citations