Accuracy of DNA polymerase-alpha in copying natural DNA.

Complementary base pairing and the origin of substitution mutations

1976 • 835 citations

Spontaneous Mutation: Genetic Control of Mutation Rates in Bacteriophage T4

1969 • 206 citations

Kinetic basis of spontaneous mutation

1982 • 187 citations

A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos.

1982 • 180 citations

Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation.

1979 • 165 citations

Mutagenesis during in vitro DNA synthesis.

1978 • 147 citations

Rapid synthesis of oligodeoxyribonucleotides VII. Solid phase synthesis of oligodeoxyribonucleo-tides by a eontinuous flow phosphotriester method on a kieselguhr-polyamide support

1982 • 137 citations

Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster.

1983 • 132 citations

On the fidelity of DNA replication. Effect of the next nucleotide on proofreading.

1981 • 107 citations

Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis.

1981 • 101 citations

DNA polymerase accuracy and spontaneous mutation rates: frequencies of purine.purine, purine.pyrimidine, and pyrimidine.pyrimidine mismatches during DNA replication.

1981 • 91 citations

The energy relay: a proofreading scheme based on dynamic cooperativity and lacking all characteristic symptoms of kinetic proofreading in DNA replication and protein synthesis.

1980 • 91 citations

Purification of a 9S DNA polymerase .alpha. species from calf thymus

1981 • 73 citations

Studies on the mechanism of DNA polymerase alpha. Nascent chain elongation, steady state kinetics, and the initiation phase of DNA synthesis.

1981 • 71 citations

Fidelity of replication of bacteriophage X174 DNA in vitro and in Vivo

1983 • 63 citations

Molecular mechanisms of substitution mutagenesis. An experimental test of the Watson-Crick and topal-fresco models of base mispairings.

1981 • 62 citations

Asymmetric information transfer during φX174 DNA replication

1972 • 61 citations

The sequence of a region of bacteriophage φX174 DNA coding for parts of genes A and B

1977 • 58 citations

Kinetics of base misinsertion by DNA polymerase I of Escherichia coli

1983 • 44 citations