Mutagenicity of quinones: pathways of metabolic activation and detoxification.

Revised methods for the Salmonella mutagenicity test

1983 • 7,295 citations

Dietary Carcinogens and Anticarcinogens

1983 • 3,028 citations

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

1977 • 854 citations

A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens.

1982 • 747 citations

Toxic drug effects associated with oxygen metabolism: Redox cycling and lipid peroxidation

1981 • 650 citations

A general mechanism for microsomal activation of quinone anticancer agents to free radicals.

1978 • 645 citations

A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds

1980 • 585 citations

DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

1982 • 530 citations

Sampling of vehicle emissions for chemical analysis and biological testing.

1983 • 457 citations

One-electron-transfer reactions in biochemical systems V. Difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase)

1970 • 335 citations

Naturally occurring quinones as potential bioreductive alkylating agents

1981 • 214 citations

A quantitative test for superoxide radicals produced in biological systems

1982 • 182 citations

Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: Relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity

1983 • 180 citations

Benzo[a]pyrenedione/benzo[a]pyrenediol oxidation-reduction couples and the generation of reactive reduced molecular oxygen

1977 • 158 citations

Quinone-stimulated superoxide formation by subcellular fractions, isolated hepatocytes, and other cells.

1981 • 119 citations

Metabolism of benzo(a)pyrene-3,6-quinone and 3-hydroxybenzo(a)pyrene in liver microsomes from 3-methylcholanthrene-treated rats

1978 • 115 citations

SKF 525-A inhibition, induction, and 452-nm complex formation.

1976 • 110 citations

Structure-antitumor activity relationships among quinone derivatives.

1974 • 85 citations

Potential bioreductive alkylating agents. 2. Antitumor effect and biochemical studies of naphthoquinone derivatives

1973 • 80 citations

The history, properties, and function of NADPH-cytochrome P-450 reductase

1980 • 72 citations

Benzo(α)pyrene quinones can be generated by lipid peroxidation and are conjugated with glutathione by glutathione S-transferase B from rat liver

1981 • 60 citations

Mutagenicity of natural naphthoquinones and benzoquinones in the Salmonella/microsome test

1983 • 58 citations

Cytocidal action of the quinone group and its relationship to antitumor activity.

1983 • 54 citations

Mutagenicity of anthraquinone and hydroxylated anthraquinones in the Ames/Salmonella microsome system

1982 • 38 citations

Possible role of DT-diaphorase in the bioactivation of antitumor quinones

1983 • 37 citations

Interaction of benzo- and naphtoquinones with soluble glutathione S-tranferases from rat liver

1983 • 24 citations

[66] Detection and measurement of drug-induced oxygen radical formation

1984 • 15 citations

ChemInform Abstract: NATURALLY OCCURRING QUINONES AS POTENTIAL BIOREDUCTIVE ALKYLATING AGENTS

1982 • 5 citations