The selectins: Insights into selectin-induced intracellular signaling in leukocytes

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Evaluation of High-Sensitivity C-Reactive Protein and Serum Lipid Profile in Southeastern Nigerian Women with Pre-Eclampsia

2015 • 2,005 citations

Circulating adhesion molecules in disease

1993 • 1,425 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

Selectins: Interpreters of Cell-Specific Carbohydrate Information During Inflammation

1992 • 1,255 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

The selecting: vascular adhesion molecules

1995 • 954 citations

Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor

1991 • 878 citations

PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes

1989 • 878 citations

Selectins.

1993 • 869 citations

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion

1994 • 863 citations

Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice

1994 • 835 citations

Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

1992 • 800 citations

Endothelial cell interactions with granulocytes: tethering and signaling molecules

1992 • 773 citations

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

1992 • 698 citations

Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies.

1990 • 678 citations

The chemotactic receptor for human C5a anaphylatoxin

1991 • 660 citations

P-selectin induces the expression of tissue factor on monocytes.

1994 • 595 citations

The pathway to signal achievement

1993 • 563 citations

L-selectin-mediated lymphocyte rolling on MAdCAM-1

1993 • 540 citations

High endothelial venules (HEVs): specialized endothelium for lymphocyte migration

1995 • 539 citations

PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells

1989 • 538 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 473 citations

Involvement of Platelet-Endothelial Cell Adhesion Molecule-1 in Neutrophil Recruitment in Vivo

1993 • 468 citations

Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.

1990 • 447 citations

Chemotactic factors regulate lectin adhesion molecule 1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro.

1991 • 439 citations

Transforming growth factor-alpha. A model for membrane-anchored growth factors.

1990 • 430 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

1991 • 406 citations

Characterization of E-selectin-deficient mice: Demonstration of overlapping function of the endothelial selectins

1994 • 384 citations

Lipid second messengers

1994 • 357 citations

Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils.

1991 • 347 citations

Inflammatory roles of P-selectin.

1993 • 336 citations

The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors

1990 • 323 citations

Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1

1991 • 318 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.

1989 • 308 citations

CD62/P-selectin recognition of myeloid and tumor cell sulfatides

1991 • 304 citations

Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling.

1995 • 295 citations

Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor.

1992 • 287 citations

Characterization of a specific ligand for P-selectin on myeloid cells. A minor glycoprotein with sialylated O-linked oligosaccharides

1993 • 274 citations

E-selectin supports neutrophil rolling in vitro under conditions of flow.

1993 • 273 citations

Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venules.

1993 • 271 citations

Transmembrane signaling: the joy of aggregation.

1992 • 267 citations

Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody.

1994 • 267 citations

Prevention of Activated Neutrophil Adhesion to Endothelium by Soluble Adhesion Protein GMP140

1990 • 257 citations

Structural requirements for the carbohydrate ligand of E-selectin.

1991 • 242 citations

The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development

1995 • 240 citations

L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo

1992 • 239 citations

Activated platelets induce superoxide anion release by monocytes and neutrophils through P-selectin (CD62).

1993 • 228 citations

L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin.

1995 • 228 citations

P-selectin and vascular cell adhesion molecule 1 mediate rolling and arrest, respectively, of CD4+ T lymphocytes on tumor necrosis factor α-activated vascular endothelium under flow.

1995 • 223 citations

The Src family of tyrosine protein kinases in hemopoietic signal transduction

1992 • 221 citations

Receptor Binding and Activation of Polymorphonuclear Neutrophils by Tumor Necrosis Factor-Alpha

1987 • 219 citations

Selectins

1994 • 207 citations

Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin.

1993 • 206 citations

GMP-140 binding to neutrophils is inhibited by sulfated glycans.

1991 • 202 citations

Identification of a glycoprotein ligand for E-selectin on mouse myeloid cells.

1993 • 201 citations

In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes.

1993 • 199 citations

Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin.

1994 • 198 citations

Signaling Functions of L-selectin

1995 • 190 citations

THE SITE OF LEUCOCYTE EMIGRATION DURING INFLAMMATION

1961 • 190 citations

Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-alpha and interleukin-8 mRNA in human neutrophils. Evidence for a role of L-selectin as a signaling molecule.

1994 • 188 citations

The Many Roads That Lead to Ras

1993 • 185 citations

The HNK-1 reactive sulfoglucuronyl glycolipids are ligands for L-selectin and P-selectin but not E-selectin.

1993 • 182 citations

Divergent fates of P- and E-selectins after their expression on the plasma membrane.

1993 • 181 citations

Comparison of L-selectin and E-selectin ligand specificities: The L-selectin can bind the E-selectin ligands Sialyl Lex and Sialyl Lea

1992 • 179 citations

Structural requirements regulate endoproteolytic release of the L-selectin (CD62L) adhesion receptor from the cell surface of leukocytes.

1995 • 168 citations

Higher-affinity oligosaccharide ligands for E-selectin.

1993 • 166 citations

Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectin

1994 • 163 citations

A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.

1990 • 162 citations

Activation of human neutrophils through L-selectin and Mac-1 molecules.

1995 • 159 citations

My-1, the human myeloid-specific antigen detected by mouse monoclonal antibodies, is a sugar sequence found in lacto-N-fucopentaose III

1983 • 139 citations

Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin density.

1992 • 130 citations

A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion

1994 • 124 citations

Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration.

1991 • 121 citations

Compartmentalized roles for leukocytic adhesion molecules in lung inflammatory injury.

1995 • 115 citations

A novel carbohydrate, differentiation antigen on fucogangliosides of human myeloid cells recognized by monoclonal antibody VIM-2.

1988 • 108 citations

Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils.

1991 • 107 citations

Bovine gamma/delta T cells bind E-selectin via a novel glycoprotein receptor: first characterization of a lymphocyte/E-selectin interaction in an animal model.

1993 • 99 citations

Soluble and insoluble immune complexes activate human neutrophil NADPH oxidase by distinct Fc gamma receptor-specific mechanisms.

1990 • 99 citations

The peripheral lymph node homing receptor, LECAM-1, is involved in CD18-independent adhesion of human neutrophils to endothelium

1991 • 93 citations

Low-dose chymotrypsin treatment inhibits neutrophil migration into sites of inflammation in vivo: Effects on Mac-1 and MEL-14 adhesion protein expression and function

1991 • 93 citations

Granulocyte migration through endothelium in culture.

1979 • 91 citations

Neutrophil aggregation is beta 2-integrin- and L-selectin-dependent in blood and isolated cells.

1992 • 90 citations

Induction of superoxide anion production from monocytes and neutrophils by activated platelets through the P-selectin–sialyl Lewis X interaction

1994 • 88 citations

A novel role for E- and P-selectins: shape control of endothelial cell monolayers

1994 • 79 citations

Cell surface P- and E-selectin support shear-dependent rolling of bovine gamma/delta T cells.

1994 • 77 citations

CD62/P-Selectin Binding Sites for Myeloid Cells and Sulfatides Are Overlapping

1994 • 74 citations

Lectin domain peptides from selectins interact with both cell surface ligands and Ca2+ ions.

1992 • 73 citations

Protein synthesis dependent and independent mechanisms of neutrophil emigration. Different mechanisms of inflammation in rabbits induced by interleukin-1, tumor necrosis factor alpha or endotoxin versus leukocyte chemoattractants.

1989 • 58 citations

Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65).

1992 • 55 citations

Role of ELAM‐1 in Adhesion of Monocytes to Activated Human Endothelial Cells

1992 • 51 citations

Margination and Emigration of Leucocytes

1985 • 47 citations

Structure and function of L‐selectin

1992 • 45 citations

Receptors and Intracellular Signaling in Human Neutrophils

1990 • 44 citations

Lectin and epidermal growth factor domains of P-selectin at physiologic density are the recognition unit for leukocyte binding

1995 • 39 citations

The role of G-proteins versus protein tyrosine kinases in the regulation of lymphocyte activation

1992 • 39 citations

Granulocyte migration through endothelium in culture

1979 • 31 citations

PMN binding to P-selectin is inhibited by sulfatide

1992 • 28 citations

Phosphorylation of surface E‐selectin and the effect of soluble ligand (Sialyl Lewis^x) on the half‐life of E‐selectin

1993 • 28 citations

Adhesion Molecules and the Lung

1996 • 17 citations

L-Selectin mediates downregulation of neutrophil TNF receptors

1994 • 10 citations

Molecular Cloning of the Human Neurokinin‐2 Receptor cDNA by Polymerase Chain Reaction and Isolation of the Genea

1991 • 6 citations