Lectin and epidermal growth factor domains of P-selectin at physiologic density are the recognition unit for leukocyte binding

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

1990 • 997 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation.

1985 • 886 citations

PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes

1989 • 878 citations

Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

1992 • 800 citations

Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

1989 • 799 citations

Expression cloning of a functional glycoprotein ligand for P-selectin

1993 • 734 citations

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

1992 • 698 citations

An endothelial ligand for L-Selectin is a novel mucin-like molecule

1992 • 660 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140

1991 • 592 citations

PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells

1989 • 538 citations

Cloning of a lymphocyte homing receptor reveals a lectin domain

1989 • 522 citations

Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.

1992 • 519 citations

GMP-140 mediates adhesion of stimulated platelets to neutrophils

1990 • 515 citations

CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.

1991 • 505 citations

A monoclonal antibody to a membrane glycoprotein binds only to activated platelets.

1984 • 456 citations

Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains

1989 • 428 citations

A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets.

1984 • 426 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

1991 • 406 citations

A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein.

1986 • 402 citations

The Phosphorylation State of Eucaryotic Initiation Factor 2 Alters Translational Efficiency of Specific mRNAs

1989 • 393 citations

PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15)

1990 • 367 citations

Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.

1989 • 308 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

CD62/P-selectin recognition of myeloid and tumor cell sulfatides

1991 • 304 citations

Structural and functional characterization of monomeric soluble P-selectin and comparison with membrane P-selectin

1993 • 297 citations

Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor–IgG chimaera

1991 • 293 citations

GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interaction.

1991 • 247 citations

Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein

1992 • 237 citations

Isolation and Quantitation of the Platelet Membrane Glycoprotein Deficient in Thrombasthenia Using a Monoclonal Hybridoma Antibody

1980 • 209 citations

GMP-140 binding to neutrophils is inhibited by sulfated glycans.

1991 • 202 citations

Identification of a glycoprotein ligand for E-selectin on mouse myeloid cells.

1993 • 201 citations

Structure of human platelet membrane glycoproteins IIb and IIIa as determined by electron microscopy.

1985 • 194 citations

The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.

1991 • 175 citations

CD66 nonspecific cross-reacting antigens are involved in neutrophil adherence to cytokine-activated endothelial cells.

1992 • 168 citations

P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.

1992 • 160 citations

P- and E-selectin use common sites for carbohydrate ligand recognition and cell adhesion.

1993 • 150 citations

Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin density.

1992 • 130 citations

ELISA for quantitation of l-selectin shed from leukocytes in vivo

1992 • 127 citations

A role for the epidermal growth factor-like domain of P-selectin in ligand recognition and cell adhesion

1994 • 124 citations

Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration.

1991 • 121 citations

The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: Role of the EGF domain in endothelial binding

1990 • 117 citations

Molecular mapping of functional domains of the leukocyte receptor for endothelium, LAM-1.

1991 • 97 citations

Granule membrane protein 140 (GMP140) binds to carcinomas and carcinoma-derived cell lines.

1992 • 93 citations

Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres).

1992 • 88 citations

Lectin domain peptides from selectins interact with both cell surface ligands and Ca2+ ions.

1992 • 73 citations

Rapid phosphorylation and selective dephosphorylation of P-selectin accompanies platelet activation

1993 • 53 citations

The cytoplasmic domain of P-selectin is phosphorylated on serine and threonine residues

1993 • 48 citations