Cytoskeleton organization and submembranous interactions in intestinal and renal brush borders

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

A 130K protein from chicken gizzard: Its localization at the termini of microfilament bundles in cultured chicken cells

1979 • 794 citations

Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review

1979 • 765 citations

Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cells.

1975 • 615 citations

The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border.

1982 • 539 citations

Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats

1983 • 496 citations

Ischemic damage and repair in the rat proximal tubule: Differences among the S1, S2, and S3 segments

1978 • 490 citations

Membrane Recycling by Coated Vesicles

1981 • 450 citations

Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

1980 • 444 citations

Topology of microvillar membrance hydrolases of kidney and intestine.

1982 • 437 citations

Anchoring and Biosynthesis of Stalked Brush Border Membrane Proteins: Glycosidases and Peptidases of Enterocytes and Renal Tubuli

1986 • 405 citations

Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells.

1981 • 386 citations

Identification and Characterization of Epithelial Cells in Mammalian Tissues by Immunofluorescence Microscopy Using Antibodies to Prekeratin

1979 • 348 citations

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures.

1980 • 306 citations

Identification and organization of the components in the isolated microvillus cytoskeleton.

1979 • 303 citations

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats

1986 • 297 citations

Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells.

1983 • 294 citations

An F-actin- and calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin

1982 • 276 citations

Quick-freeze, deep-etch visualization of the cytoskeleton beneath surface differentiations of intestinal epithelial cells.

1981 • 267 citations

The terminal web. A reevaluation of its structure and function.

1979 • 243 citations

Specimen preparation for electron microscopy using low temperature embedding resins

1982 • 240 citations

Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy.

1978 • 232 citations

Assembly polypeptides from coated vesicles mediate reassembly of unique clathrin coats.

1983 • 228 citations

F-actin binding and bundling properties of fimbrin, a major cytoskeletal protein of microvillus core filaments.

1981 • 214 citations

Calcium-dependent conformational changes in the 36-kDa subunit of intestinal protein I related to the cellular 36-kDa target of Rous sarcoma virus tyrosine kinase.

1985 • 200 citations

Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells?

1985 • 193 citations

Fodrin is the general spectrin-like protein found in most cells whereas spectrin and the TW protein have a restricted distribution

1983 • 191 citations

Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells.

1980 • 176 citations

Microdomains of distinctive glycoprotein composition in the kidney proximal tubule brush border.

1984 • 174 citations

The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.

1986 • 173 citations

Identification and localization of immunoreactive forms of caldesmon in smooth and nonmuscle cells: a comparison with the distributions of tropomyosin and alpha-actinin.

1985 • 170 citations

F actin assembly modulated by villin: Ca++-dependent nucleation and capping of the barbed end

1981 • 167 citations

Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium.

1976 • 165 citations

Actin in the Brush-Border of Epithelial Cells of the Chicken Intestine

1971 • 165 citations

Regulation of actin polymerization by villin, a 95,000 dalton cytoskeletal component of intestinal brush borders

1980 • 149 citations

Mechanism of brush border contractility studied by the quick-freeze, deep-etch method.

1983 • 149 citations

Changes in villin synthesis and subcellular distribution during intestinal differentiation of HT29-18 clones.

1987 • 146 citations

The 110,000-dalton actin- and calmodulin-binding protein from intestinal brush border is a myosin-like ATPase.

1984 • 138 citations

Localization of myosin, actin, and tropomyosin in rat intestinal epithelium: immunohistochemical studies at the light and electron microscope levels.

1980 • 137 citations

Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli.

1983 • 136 citations

Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. II. Extrarenal distribution.

1986 • 131 citations

Characterization and localization of myosin in the brush border of intestinal epithelial cells

1978 • 131 citations

Isolation and characterization of desmosome-associated tonofilaments from rat intestinal brush border.

1981 • 129 citations

Characterization of the 110-kdalton actin-calmodulin-, and membrane-binding protein from microvilli of intestinal epithelial cells.

1983 • 121 citations

A procedure for the isolation of the epithelial brush border membrane of hamster small intestine

1961 • 118 citations

Renal tubular uptake of protein: effect of molecular charge

1983 • 118 citations

alpha-Actinin localization in the junctional complex of intestinal epithelial cells.

1979 • 116 citations

Demonstration of at least two different actin-binding sites in villin, a calcium-regulated modulator of F-actin organization.

1981 • 115 citations

Distribution of actin and the actin-associated proteins myosin, tropomyosin, alpha-actinin, vinculin, and villin in rat and bovine exocrine glands.

1983 • 114 citations

Kinetics, competition, and selectivity of tubular absorption of proteins

1982 • 111 citations

Reactivation of intestinal epithelial cell brush border motility: ATP-dependent contraction via a terminal web contractile ring.

1982 • 109 citations

Renal Receptors for Calcitonin

1973 • 105 citations

The 46,000-dalton tyrosine protein kinase substrate is widespread, whereas the 36,000-dalton substrate is only expressed at high levels in certain rodent tissues.

1984 • 103 citations

Villin: a cytoskeletal protein and a differentiation marker expressed in some human adenocarcinomas

1987 • 102 citations

A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture.

1986 • 98 citations

Partial reconstruction of the microvillus core bundle: characterization of villin as a Ca(++)-dependent, actin-bundling/depolymerizing protein

1982 • 96 citations

Effect of villin on the kinetics of actin polymerization

1984 • 95 citations

Rapid membrane recycling in renal proximal tubule cells.

1982 • 95 citations

Role of fimbrin and villin in determining the interfilament distances of actin bundles

1983 • 94 citations

Development of the structural components of the brush border in absorptive cells of the chick intestine

1979 • 86 citations

Presence of an extensive clathrin coat on the apical plasmalemma of the rat kidney proximal tubule cell.

1984 • 86 citations

Mechanism of proximal tubule brush border loss and regeneration following mild renal ischemia.

1981 • 85 citations

Immunocytochemical localization of alpha-actinin in intestinal epithelial cells.

1979 • 82 citations

Effect of molecular charge on endocytic uptake of ferritin in renal proximal tubule cells.

1981 • 81 citations

The membrane composition of coated pits, microvilli, endosomes, and lysosomes is distinctive in the rat kidney proximal tubule cell.

1986 • 81 citations

Antibody-mediated injury to proximal tubules in Heymann nephritis

1980 • 76 citations

Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin

1981 • 75 citations

Proteins of the kidney microvillus membrane. Identification of subunits after sodium dodecylsullphate/polyacrylamide-gel electrophoresis

1976 • 72 citations

Tropomyosin distinguishes between the two actin-binding sites of villin and affects actin-binding properties of other brush border proteins.

1987 • 69 citations

Changes in the distribution of the 34-kdalton tyrosine kinase substrate during differentiation and maturation of chicken tissues.

1984 • 69 citations

Villin--a marker of brush border differentiation and cellular origin in human renal cell carcinoma.

1986 • 69 citations

Abundance, relative gelation activity, and distribution of the 95,000-dalton actin-binding protein from Dictyostelium discoideum.

1983 • 67 citations

The microvillus 110K cytoskeletal protein is an integral membrane protein

1984 • 66 citations

Insulin Binding and Degradation by Luminal and Basolateral Tubular Membranes from Rabbit Kidney

1982 • 64 citations

Analysis of the pinocytic process in rat kidney II. Biochemical composition of pinocytic vesicles compared to brush border microvilli, lysosomes and basolateral plasma membranes

1976 • 63 citations

A gelsolin-like Ca2+-dependent actin-binding domain in villin

1985 • 63 citations

Endocytosis in kidney proximal tubule cells and cultured fibroblasts: a review of the structural aspects of membrane recycling between the plasma membrane and endocytic vacuoles.

1984 • 59 citations

Cellular mechanisms of tubular protein transport.

1976 • 59 citations

Studies on the spectrin-like protein from the intestinal brush border, TW 260/240, and characterization of its interaction with the cytoskeleton and actin.

1984 • 54 citations

Cytoskeletal proteins of the rat kidney proximal tubule brush border.

1986 • 52 citations

ANALYSIS OF THE PINOCYTIC PROCESS IN RAT KIDNEY

1974 • 50 citations

Calcium dependence of villin-induced actin depolymerization

1984 • 50 citations

Isolation of brush border fragments from homogenates of rat and rabbit kidney cortex

1968 • 49 citations

Spectrin, fodrin, and TW260/240: A family of related proteins lining the plasma membrane

1983 • 48 citations

Proteinuria induced by sodium maleate in rats: Effects on ultrastructure and protein handling in renal proximal tubule

1980 • 45 citations

Ligand-induced conformational changes in villin, a calcium-controlled actin-modulating protein.

1983 • 43 citations

Isolation and characterization of mammalian villin and fimbrin, the two bundling proteins of the intestinal microvilli.

1983 • 32 citations

Binding and Degradation of Insulin by Isolated Renal Brush Border Membranes

1982 • 32 citations

Interactions of a protease inhibitor and other peptides with isolated brush border membranes from rat renal cortex

1973 • 30 citations

Surface and cytoplasmic domains in polarized epithelial cells.

1982 • 27 citations

The structure of an unusual leghemoglobin gene from soybean.

1983 • 26 citations

Passively transferred anti-brush border antibodies induce injury of proximal tubules in the absence of complement.

1984 • 19 citations

Effects of villin on the polymerization and subunit exchange of actin

1983 • 19 citations

The dynamic interrelationships of actin and vinculin in cultured cells

1983 • 16 citations

Reevaluation of the hydrophobic nature of the 110‐kD calmodulin‐, actin‐, and membrane‐binding protein of the intestinal microvillus

1986 • 15 citations

Actin assembly and filament cross‐linking in the presence of TW 260/240, the tissue‐specific spectrin of the chicken intestinal brush border

1985 • 13 citations

The role of brush border enzymes in tubular reabsorption of disaccharides

1977 • 11 citations

Altered reabsorption of protein by the renal cortex in rats treated with hypertonic saline or mannitol.

1975 • 9 citations