Secretory traffic in the eukaryotic parasite Toxoplasma gondii

Toxoplasmic Encephalitis in AIDS

1992 • 1,293 citations

Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

1999 • 1,175 citations

A Plastid of Probable Green Algal Origin in Apicomplexan Parasites

1997 • 754 citations

Nuclear-encoded proteins target to the plastid inToxoplasma gondiiandPlasmodium falciparum

1998 • 705 citations

Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts.

1997 • 650 citations

Chapter 3: Molecular Tools for Genetic Dissection of the Protozoan Parasite Toxoplasma gondii

1995 • 592 citations

A plastid organelle as a drug target in apicomplexan parasites

1997 • 589 citations

Complete Gene Map of the Plastid-like DNA of the Malaria ParasitePlasmodium falciparum

1996 • 560 citations

Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway

2000 • 536 citations

Sorting and storage during secretory granule biogenesis: looking backward and looking forward

1998 • 516 citations

Lysosome‐related organelles

2000 • 467 citations

Toxoplasma gondii : Fusion Competence of Parasitophorous Vacuoles in Fc Receptor-Transfected Fibroblasts

1990 • 446 citations

Molecular Bases for the Recognition of Tyrosine-based Sorting Signals

1999 • 414 citations

Association of host cell endoplasmic reticulum and mitochondria with the Toxoplasma gondii parasitophorous vacuole membrane: A high affinity interaction

1997 • 314 citations

Golgi Structure Correlates with Transitional Endoplasmic Reticulum Organization in Pichia pastoris and Saccharomyces cerevisiae

1999 • 313 citations

Phagosome acidification blocked by intracellular Toxoplasma gondii

1985 • 295 citations

Lysosome-related organelles

2000 • 288 citations

Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore.

1996 • 288 citations

Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole

2001 • 284 citations

Conservation of a Gliding Motility and Cell Invasion Machinery in Apicomplexan Parasites

1999 • 284 citations

Secretory granule biogenesis: rafting to the SNARE

2001 • 256 citations

ATPase-defective Mammalian VPS4 Localizes to Aberrant Endosomes and Impairs Cholesterol Trafficking

2000 • 249 citations

The Plastid of Toxoplasma gondii Is Divided by Association with the Centrosomes

2000 • 234 citations

Toxoplasma gondii Resides in a Vacuole That Avoids Fusion with Host Cell Endocytic and Exocytic Vesicular Trafficking Pathways

1999 • 206 citations

A novel polymer of tubulin forms the conoid of Toxoplasma gondii

2002 • 200 citations

Identification and Characterization of an Escorter for Two Secretory Adhesins in Toxoplasma gondii

2001 • 196 citations

The Toxoplasma Adhesive Protein MIC2 Is Proteolytically Processed at Multiple Sites by Two Parasite-derived Proteases

2000 • 191 citations

Kinetics and pattern of organelle exocytosis duringToxoplasma gondii/host-cell interaction

1993 • 190 citations

Defining the cell cycle for the tachyzoite stage of Toxoplasma gondii

2001 • 189 citations

Expression, selection, and organellar targeting of the green fluorescent protein in Toxoplasma gondii

1998 • 183 citations

Gene Discovery by EST Sequencing inToxoplasma gondiiReveals Sequences Restricted to the Apicomplexa

1998 • 182 citations

Daughter Cell Assembly in the Protozoan ParasiteToxoplasma gondii

2002 • 181 citations

The nuclear envelope serves as an intermediary between the ER and Golgi complex in the intracellular parasite Toxoplasma gondii

1999 • 173 citations

A plastid segregation defect in the protozoan parasite Toxoplasma gondii

2001 • 170 citations

A family of transmembrane microneme proteins ofToxoplasma gondiicontain EGF-like domains and function as escorters

2002 • 167 citations

Acidocalcisomes in Toxoplasma gondii tachyzoites

1996 • 157 citations

Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii

2001 • 147 citations

Origin, targeting, and function of the apicomplexan plastid

1999 • 146 citations

The Toxoplasma Micronemal Protein MIC4 Is an Adhesin Composed of Six Conserved Apple Domains

2001 • 143 citations

Progress in Taxonomy of the Apicomplexan Protozoa

1988 • 142 citations

Inhibition ofToxoplasma gondiiReplication by Dinitroaniline Herbicides

1996 • 142 citations

Measuring tubulin content in Toxoplasma gondii : A comparison of laser-scanning confocal and wide-field fluorescence microscopy

2002 • 135 citations

Genetic complementation in apicomplexan parasites

2002 • 130 citations

PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished)

2002 • 130 citations

Analysis of targeting sequences demonstrates that trafficking to the Toxoplasma gondii plastid branches off the secretory system

2000 • 127 citations

RAP1 controls rhoptry targeting of RAP2 in the malaria parasite Plasmodium falciparum

2000 • 127 citations

The microneme protein MIC3 of Toxoplasma gondii is a secretory adhesin that binds to both the surface of the host cells and the surface of the parasite

2000 • 126 citations

THE EXTRACHROMOSOMAL DNAS OF APICOMPLEXAN PARASITES

1994 • 121 citations

Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms.

2000 • 121 citations

The Protozoan Parasite Toxoplasma gondii Targets Proteins to Dense Granules and the Vacuolar Space Using Both Conserved and Unusual Mechanisms

1998 • 120 citations

TgM2AP participates in Toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2

2001 • 115 citations

Subcellular localization of acetyl-CoA carboxylase in the apicomplexan parasite Toxoplasma gondii

2001 • 109 citations

Targeting of soluble proteins to the rhoptries and micronemes in Toxoplasma gondii

2001 • 96 citations

Two Conserved Amino Acid Motifs Mediate Protein Targeting to the Micronemes of the Apicomplexan Parasite Toxoplasma gondii

2000 • 95 citations

Processing of Toxoplasma ROP1 protein in nascent rhoptries

1998 • 93 citations

Characterization of the lipid content ofToxoplasma gondiirhoptries

1991 • 92 citations

Endocytosis at the micropore ofToxoplasma gondii

1994 • 71 citations

Cell Invasion by Un‐Palatable Parasites

2000 • 70 citations

Targeted Reduction of Nucleoside Triphosphate Hydrolase by Antisense RNA Inhibits Toxoplasma gondii Proliferation

1999 • 70 citations

Differential sorting and post-secretory targeting of proteins in parasitic invasion

2000 • 69 citations

Constitutive Calcium-independent Release of Toxoplasma gondii Dense Granules Occurs through the NSF/SNAP/SNARE/Rab Machinery

1999 • 66 citations

Acidic compartments and rhoptry formation in Toxoplasma gondii

1998 • 61 citations

Toxoplasma gondii Rab5 enhances cholesterol acquisition from host cells

2002 • 60 citations

The pro region of Toxoplasma ROP1 is a rhoptry-targeting signal

2001 • 54 citations

Intracellular trafficking of dense granule proteins in Toxoplasma gondii and experimental evidences for a regulated exocytosis

1999 • 51 citations

Development of a Stable Episomal Shuttle Vector for Toxoplasma gondii

1998 • 42 citations

Analysis of apicoplast targeting and transit peptide processing in Toxoplasma gondii by deletional and insertional mutagenesis

2001 • 40 citations

[1] Forward and reverse genetics in the study of the obligate, intracellular parasite Toxoplasma gondii

1995 • 34 citations

Toxoplasma gondii ADP-ribosylation Factor 1 Mediates Enhanced Release of Constitutively Secreted Dense Granule Proteins

2001 • 25 citations

Cytoplasmic tail motifs mediate endoplasmic reticulum localization and export of transmembrane reporters in the protozoan parasite Toxoplasma gondii

2000 • 23 citations