The crystal structure of pertussis toxin

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

Stereochemical quality of protein structure coordinates

1992 • 1,503 citations

OB(oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences.

1993 • 917 citations

Structure of a C-type mannose-binding protein complexed with an oligosaccharide

1992 • 873 citations

The detection and classification of membrane-spanning proteins

1985 • 854 citations

Nicotinic Acetylcholine Receptor an 9 Å Resolution

1993 • 822 citations

Using known substructures in protein model building and crystallography.

1986 • 766 citations

The crystal structure of diphtheria toxin

1992 • 663 citations

Surface, subunit interfaces and interior of oligomeric proteins

1988 • 644 citations

Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli

1991 • 556 citations

Structure of the Calcium-Dependent Lectin Domain from a Rat Mannose-Binding Protein Determined by MAD Phasing

1991 • 547 citations

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution.

1986 • 517 citations

Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model

1982 • 497 citations

Pertussis Toxin Gene: Nucleotide Sequence and Genetic Organization

1986 • 364 citations

Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.

1986 • 343 citations

Refined Structure of Escherichia coli Heat-labile Enterotoxin, a Close Relative of Cholera Toxin

1993 • 299 citations

Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli

1992 • 288 citations

Neurological complications of pertussis inoculation

1974 • 271 citations

The concept of pertussis as a toxin-mediated disease

1984 • 262 citations

A role of the B-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells.

1983 • 227 citations

Characterization of Two Adhesins of Bordetella pertussis for Human Ciliated Respiratory-Epithelial Cells

1985 • 224 citations

Bordetella pertussis infection in mice: correlation of specific antibodies against two antigens, pertussis toxin, and filamentous hemagglutinin with mouse protectivity in an intracerebral or aerosol challenge system

1984 • 174 citations

2·2 Å resolution structure analysis of two refined N-acetylneuraminyl-lactose—Wheat germ agglutinin isolectin complexes

1990 • 162 citations

Activation by thiol of the latent NAD glycohydrolase and ADP-ribosyltransferase activities of Bordetella pertussis toxin (islet-activating protein).

1983 • 148 citations

A phased translation function

1988 • 145 citations

Pertussis toxin has eukaryotic-like carbohydrate recognition domains.

1992 • 143 citations

Mouse-protecting and histamine-sensitizing activities of pertussigen and fimbrial hemagglutinin from Bordetella pertussis

1981 • 131 citations

The processing of diffraction data taken on a screenless Weissenberg camera for macromolecular crystallography

1989 • 119 citations

Binding of pertussis toxin to eucaryotic cells and glycoproteins

1989 • 119 citations

Lectin-like binding of pertussis toxin to a 165-kilodalton Chinese hamster ovary cell glycoprotein.

1988 • 113 citations

Pertussis Toxin S1 Mutant with Reduced Enzyme Activity and a Conserved Protective Epitope

1988 • 113 citations

A focusing Weissenberg camera with multi-layer-line screens for macromolecular crystallography

1983 • 111 citations

Separation and characterization of two distinct hemagglutinins contained in purified leukocytosis-promoting factor from Bordetella pertussis

1976 • 106 citations

Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity.

1988 • 105 citations

Adenine nucleotides promote dissociation of pertussis toxin subunits.

1986 • 72 citations

Site-specific alterations in the B oligomer that affect receptor-binding activities and mitogenicity of pertussis toxin.

1993 • 67 citations

Stimulation of the thiol-dependent ADP-ribosyltransferase and NAD glycohydrolase activities of Bordetella pertussis toxin by adenine nucleotides, phospholipids, and detergents

1986 • 64 citations

ADP-ribosyltransferase mutations in the catalytic S-1 subunit of pertussis toxin

1988 • 61 citations

Pertussis vaccine and injury to the brain

1990 • 60 citations

Use of glycosyltransferases to restore pertussis toxin receptor activity to asialoagalactofetuin.

1988 • 55 citations

Protein architecture: new superfamilies

1992 • 50 citations

Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine

1990 • 48 citations

Comparison of the B-pentamers of heat-labile enterotoxin and verotoxin-1: two structures with remarkable similarity and dissimilarity

1993 • 46 citations

Structural characterization of pertussis toxin A subunit.

1987 • 45 citations

Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.

1989 • 43 citations

Identification of an active‐site residue in subunit S1 of pertussis toxin by photocrosslinking to NAD

1989 • 41 citations

Alkylation of Cysteine 41, but Not Cysteine 200, Decreases the ADP-ribosytransferase Activity of the S1 Subunit of Pertussis Toxin

1989 • 37 citations

Investigation of the lectin-like binding domains in pertussis toxin using synthetic peptide sequences. Identification of a sialic acid binding site in the S2 subunit of the toxin.

1992 • 35 citations

Characterization of pertussis toxin analogs containing mutations in B-oligomer subunits

1993 • 33 citations

Protein‐chemical analysis of pertussis toxin reveals homology between the subunits S₂ and S₃, between S₁ and the A chains of enterotoxins of Vibrio cholerae and Escherichia coli and identifies S₂ as the haptoglobin‐binding subunit

1986 • 32 citations

Adverse Effects of Pertussis and Rubella Vaccines

1992 • 31 citations

Protein architecture: New superfamilies

1992 • 31 citations

Inhibition of pertussis toxin binding to model receptors by antipeptide antibodies directed at an antigenic domain of the S2 subunit

1989 • 30 citations

Role of Tryptophan 26 in the NAD Glycohydrolase Reaction of the S-1 Subunit of Pertussis Toxin

1989 • 27 citations

Role of Cysteine 41 of the A Subunit of Pertussis Toxin

1989 • 26 citations

Interaction of pertussis toxin with cells and model membranes.

1992 • 23 citations

A novel process for preparing an acellular pertussis vaccine composed of non-pyrogenic toxoids of pertussis toxin and filamentous hemagglutinin

1991 • 11 citations

Protease treatment of pertussis toxin identifies the preferential cleavage of the S1 subunit

1991 • 10 citations

Tutorial on automated Patterson interpretation to find heavy atoms

1992 • 9 citations

A unique sequence of the Bordetella pertussis toxin operon

1989 • 7 citations

Density modification: theory and practice

1992 • 6 citations

Preliminary X-ray crystallographic analysis of holotoxin from Bordetella pertussis

1990 • 3 citations