IL-15 mRNA expression is up-regulated in blood and cerebrospinal fluid mononuclear cells in multiple sclerosis (MS)

Rating neurologic impairment in multiple sclerosis

1983 • 14,011 citations

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor

1994 • 1,423 citations

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor.

1994 • 1,079 citations

Cytokines in inflammatory brain lesions: helpful and harmful

1996 • 727 citations

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor.

1995 • 627 citations

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

1997 • 513 citations

The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis

1996 • 492 citations

IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation.

1995 • 445 citations

Interleukin‐2 receptor common γ‐chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti‐apoptotic (bcl‐2, bcl‐x_L) but not pro‐apoptotic (bax, bcl‐x_S) gene expression

1996 • 367 citations

Review: cytokines and the pathogenesis of multiple sclerosis

1996 • 331 citations

Chemoattraction of human blood T lymphocytes by interleukin-15.

1995 • 303 citations

Mechanisms of Immune Injury in Multiple Sclerosis

1996 • 242 citations

Religious psychotherapy in anxiety disorder patients

1994 • 240 citations

Increased transforming growth factor‐β, interleukin‐4, and interferon‐γ in multiple sclerosis

1994 • 162 citations

Histopathology and the blood-cerebrospinal fluid barrier in multiple sclerosis

1994 • 127 citations

IL-15, an immunomodulator of T cell responses in intracellular infection.

1997 • 120 citations

Cytokine interactions in human immunodeficiency virus-infected individuals: roles of interleukin (IL)-2, IL-12, and IL-15.

1995 • 113 citations

IL-15 stimulates the expansion of AIDS virus-specific CTL.

1996 • 112 citations

Interleukin-15 gene expression in human astrocytes and microglia in culture

1996 • 107 citations

Myelin antigen reactive T cells in cerebrovascular diseases

1992 • 88 citations

Increased levels of interferon-gamma (IFN-γ), IL-4 and transforming growth factor-beta (TGF-β) mRNA expressing blood mononuclear cells in human HIV infection

1994 • 80 citations

The immunopathogenesis of multiple sclerosis and Guillain-Barré syndrome

1996 • 58 citations

Role of cytokines in multiple sclerosis and experimental autoimmune encephalomyelitis

1994 • 50 citations

Interferon-gamma, interleukin-4 and transforming growth factor-beta mRNA expression in multiple sclerosis and myasthenia gravis.

1994 • 37 citations

Cytokine mRNA profiles in mononuclear cells in acute aseptic meningoencephalitis

1995 • 17 citations