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Geometric Control of Cell Life and Death

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Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

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Adsorption of proteins onto surfaces containing end-attached oligo(ethylene oxide): a model system using self-assembled monolayers

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Integrins: Emerging Paradigms of Signal Transduction

1995 • 1,591 citations

Features of gold having micrometer to centimeter dimensions can be formed through a combination of stamping with an elastomeric stamp and an alkanethiol ‘‘ink’’ followed by chemical etching

1993 • 1,577 citations

Actin-Based Cell Motility and Cell Locomotion

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Engineering Cell Shape and Function

1994 • 1,447 citations

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

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1992 • 1,330 citations

The locomotion of fibroblasts in culture

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1987 • 653 citations

Chemotaxis in Eukaryotic Cells: A Focus on Leukocytes and Dictyostelium

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Molecular interactions in cell adhesion complexes

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Molecular insights into cancer invasion: strategies for prevention and intervention.

1995 • 500 citations

Life at the Leading Edge: The Formation of Cell Protrusions

1993 • 442 citations

Adhesion and cytoskeletal organisation of fibroblasts in response to fibronectin fragments.

1986 • 429 citations

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

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The locomotion of fibroblasts in culture I. Movements of the leading edge

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Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity.

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1979 • 244 citations

Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity.

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EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells

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A Side View of Moving Fibroblasts

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Integrin dynamics on the tail region of migrating fibroblasts

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Epidermal growth factor receptor (EGFr); results of a 6 year follow-up study in operable breast cancer with emphasis on the node negative subgroup

1991 • 171 citations

Cytokine-induced pseudopodial protrusion is coupled to tumour cell migration

1987 • 147 citations

EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism

1996 • 146 citations

Mechanisms of leukocyte motility and chemotaxis

1994 • 136 citations

Biology of human colon cancer metastasis

1995 • 132 citations

The prognostic value of epidermal growth factor receptor (EGF-R) in primary breast cancer: Results of a 10 year follow-up study

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Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix

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Expression of epidermal growth factor receptor in breast carcinoma.

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Substratum contacts and cytoskeletal reorganization of BALB/c 3T3 cells on a cell-binding fragment and heparin-binding fragments of plasma fibronectin

1986 • 111 citations

In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals

1995 • 111 citations

Focal Adhesion Kinase (p125FAK) Expression Correlates with Motility of Human Melanoma Cell Lines

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Centripetal transport of attached particles on both surfaces of moving fibroblasts

1972 • 108 citations

Molecular insights into eukaryotic chemotaxis

1991 • 103 citations

Epidermal growth factor receptor expression as a prognostic indicator in breast cancer

1991 • 100 citations

Three‐dimensional dynamics of pseudopod formation and the regulation of turning during the motility cycle of Dictyostelium

1994 • 98 citations

Epidermal growth factor receptor in human breast cancer: Correlation with steroid hormone receptors and axillary lymph node involvement

1988 • 93 citations

Integrin αvβ3 Mediates Chemotactic and Haptotactic Motility in Human Melanoma Cells through Different Signaling Pathways

1996 • 91 citations

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF‐α, bFGF, IL‐2] on glioma spheroid growth, migration and invasion

1994 • 84 citations

Locomotion ofXenopusepidermis cells in primary culture

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Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility.

1994 • 76 citations

Regulation of neutrophil motility and adhesion by intracellular calcium transients.

1993 • 70 citations

Integrin mediated signal transduction in oncogenesis: An overview

1995 • 65 citations

Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants.

1996 • 65 citations

The in vitro motility of human gliomas increases with increasing grade of malignancy

1995 • 64 citations

Metastatic competence of BW5147 T-lymphoma cell lines is correlated with in vitro invasiveness, motility and F-actin content

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Mechanisms of tumor invasion and metastasis

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Genetic approaches to cytoskeleton function and the control of cell motility

1989 • 36 citations

Cell-to-substrate adhesions during spreading and locomotion of carcinoma cells

1980 • 29 citations

Morphology of fibroblasts in collagen gels: A study using 400 keV electron microscopy and computer graphics

1989 • 29 citations

Spreading of mouse fibroblasts on the substrate with multiple spikes

1991 • 28 citations

Suppression of Ruffling by the EGF Receptor in Chemotactic Cells

1998 • 28 citations

Excess early signaling activity inhibits cellular chemotaxis toward PDGF-BB.

1994 • 25 citations

Are Growth Factors Chemotactic Agents?

1995 • 22 citations

Quantification of motility and area changes ofDictyostelium discoideum amoebae in response to chemoattractants

1988 • 16 citations

Control of stable lamellipodia formation by expression of cell surface β1,4-galactosyltransferase cytoplasmic domains

1994 • 14 citations

Locomotor properties of human germinal centre B cells: activation by anti‐CD40 and IL‐4 allows chemoattraction by anti‐immunoglobulin

1997 • 9 citations

Chapter 15 Migration and Adhesion Assays

1996 • 3 citations