Microinjection of morphine into various amygdaloid nuclei differentially affects nociceptive responsiveness and RVM neuronal activity

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Disinhibition of off-cells and antinociception produced by an opioid action within the rostral ventromedial medulla

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Peptide immunoreactive neurons in the amygdala and the bed nucleus of the stria terminalis project to the midbrain central gray in the rat

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Evidence that disinhibition of brain stem neurones contributes to morphine analgesia

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Hyperalgesia during Naloxone-Precipitated Withdrawal from Morphine Is Associated with Increased On-Cell Activity in the Rostral Ventromedial Medulla

1990 • 181 citations

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The amygdala is essential for the expression of conditional hypoalgesia.

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The central nucleus of the amygdala contributes to the production of morphine antinociception in the rat tail-flick test

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Putative pain modulating neurons in the rostral ventral medulla: Reflex-related activity predicts effects of morphine

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Antinociception following opioid stimulation of the basolateral amygdala is expressed through the periaqueductal gray and rostral ventromedial medulla

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Chapter 28 Sites of action of opiates in production of analgesia

1988 • 153 citations

Morphine microinjected into the periaqueductal gray has differential effects on 3 classes of medullary neurons

1986 • 149 citations

The central nucleus of the amygdala contributes to the production of morphine antinociception in the formalin test

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Bilateral lesions of the amygdala attenuate analgesia induced by diverse environmental challenges

1994 • 109 citations

Lesions of the periaqueductal gray and rostral ventromedial medulla disrupt antinociceptive but not cardiovascular aversive conditional responses

1994 • 106 citations

Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray

2000 • 88 citations

An electrophysiological characterization of the projection from the central nucleus of the amygdala to the periaqueductal gray of the rat: the role of opioid receptors

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Conditional hypoalgesia is attenuated by Naltrexone applied to the periaqueductal gray

1990 • 83 citations

Inhibition of the tail flick reflex following microinjection of morphine into the amygdala

1993 • 78 citations

Opioid antagonists in the periaqueductal gray inhibit morphine and β-endorphin analgesia elicited from the amygdala of rats

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Influence of intra-amygdaloid opiate injections on shock thresholds, tail-flick latencies and open field behaviour in rats

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Microinfusion of mu but not delta or kappa opioid agonists into the basolateral amygdala results in inhibition of the tail flick reflex in pentobarbital-anesthetized rats.

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Elevation of aversive threshold in rats by intra-amygdaloid injection of morphine sulphate

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The neural basis of footshock analgesia: The role of specific ventral medullary nuclei

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Physiological Survey of Medullary Raphe and Magnocellular Reticular Neurons in the Anesthetized Rat

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NMDA receptors in the midbrain periaqueductal gray mediate hypothalamically evoked hissing behavior in the cat

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Supraspinal circuitry mediating opioid antinociception: Antagonist and synergy studies in multiple sites

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Interamygdaloid projections of the basal and accessory basal nuclei of the rat amygdaloid complex

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Hypoalgesia elicited by a conditioned stimulus is blocked by a μ, but not a δ or a κ , opioid antagonist injected into the rostral ventromedial medulla

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The neural basis of footshock analgesia: The effect of periaqueductal gray lesions and decerebration

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Fos expression in the spinal cord is suppressed in rats displaying conditioned hypoalgesia.

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Fos expression in the spinal cord is suppressed in rats displaying conditioned hypoalgesia.

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The role of the basolateral nucleus of the amygdala in the pathway between the amygdala and the midbrain periaqueductal gray in the rat

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Limbic influence on the periaqueductal gray: A single unit study in the awake squirrel monkey

1984 • 24 citations

Two distinct unit activity responses to morphine in the rostral ventromedial medulla of awake rats

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Pain-Modulating Neurons and Behavioral State

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Expression of antinociception in response to a signal for shock is blocked after selective downregulation of μ-opioid receptors in the rostral ventromedial medulla

2000 • 16 citations

The effect of foot-shock on the noxious-evoked activity of neurons in the rostral ventral medulla

1990 • 7 citations