Mechanisms of Altered Hormone and Neurotransmitter Action during Aging: The Role of Impaired Calcium Mobilization

Prolonged Ca ²⁺ -Dependent Afterhyperpolarizations in Hippocampal Neurons of Aged Rats

1984 • 489 citations

Textbook of endocrinology

1982 • 388 citations

Central neurotransmitters and aging

1980 • 297 citations

Alterations in Leukocyte β-Receptor Affinity with Aging

1984 • 255 citations

Alterations in calcium content and biochemical processes in cultured skin fibroblasts from aged and Alzheimer donors.

1986 • 218 citations

Treatment Development Strategies for Alzheimer’s Disease

1987 • 198 citations

Corticosterone receptors decline in a site-specific manner in the aged rat brain

1983 • 162 citations

Correlations between membrane viscosity, serum cholesterol, lymphocyte activation and aging in man

1980 • 160 citations

Changes in the mechanisms of hormone and neurotransmitter action during aging: Current status of the role of receptor and post-receptor alterations. A review

1982 • 153 citations

Age-dependent alterations in synaptic membrane systems for Ca2+ regulation

1984 • 130 citations

Review of Biological Research in Aging

1984 • 127 citations

Aging and 3,4-diaminopyridine alter synaptosomal calcium uptake.

1983 • 118 citations

Age-dependent effects in enzyme induction- a biochemical expression of aging

1971 • 118 citations

Age-Related Changes in Specific Glucocorticoid Binding by Steroid-Responsive Tissues of Rats

1974 • 100 citations

Hormone action during aging: Alterations and mechanisms

1979 • 96 citations

Alterations in the properties of β-adrenergic receptors of myocardial membranes in aging: Impairments in agonist—receptor interactions and guanine nucleotide regulation accompany diminished catecholamine-responsiveness of adenylated cyclase

1982 • 89 citations

Immunodeficiency of aging: restorative effects of phorbol ester combined with calcium ionophore.

1986 • 87 citations

Aging Decreases the Sensitivity of Rat Cortical Synaptosomes to Calcium Ionophore‐Induced Acetylcholine Release

1986 • 74 citations

Improvement of 8-arm maze performance in aged fischer 344 rats with 3,4-diaminopyridine

1983 • 69 citations

Decreased Beta-adrenergic Agonist Affinity and Adenylate Cyclase Activity in Senescent Rat Lung

1983 • 65 citations

Age-related reduced affinity in [3H]nitrendipine labeling of brain voltage-dependent calcium channels

1985 • 65 citations

Vascular Contraction: Effect of Age and Extracellular Calcium

1976 • 61 citations

Amelioration of age-related neurochemical and behavioral deficits by 3,4-diaminopyridine

1983 • 58 citations

Modulation of rat parotid cell alpha-adrenergic responsiveness at a step subsequent to receptor activation.

1982 • 57 citations

Age related variations of some polymorphonuclear leukocyte functions

1985 • 56 citations

Do vasopressin-related peptides induce hippocampal corticosterone receptors? Implications for aging

1984 • 54 citations

Subsynaptosomal distribution of calcium during aging and 3,4-diaminopyridine treatment

1985 • 51 citations

Changes in Specific Dexamethasone Binding during Aging in WI-38 Cells*

1981 • 49 citations

Aging-associated diminished rat prostate androgen receptor content concurrent with decreased androgen dependence

1977 • 48 citations

Multiple transduction mechanisms are likely involved in calcium-mediated exocrine secretory events in rat parotid cells.

1983 • 47 citations

Reduced glucocorticoid binding site concentration in cortical neuronal perikarya from senescent rats

1976 • 45 citations

[3H] cortisol binding by young and old human liver cytosol proteins in vitro

1973 • 43 citations

Effect of senescence on Ca2+—ion transport by heart mitochondria

1982 • 42 citations

Regulation of calcium transport in cardiac cells

1984 • 40 citations

Cytoplasmic and Nuclear Binding of Estradiol in the Brain and Pituitary of Old Female Rats

1981 • 40 citations

Age-related changes in cytoplasmic estradiol receptor concentrations in microdissected brain nuclei: Correlations with changes in steroid-induced sexual behavior

1984 • 39 citations

Glucocorticoid receptors: from development to aging. A Review

1984 • 37 citations

Reduced glucocorticoid responsiveness and receptor concentration in splenic leukocytes of senescent rats

1975 • 37 citations

Neurotransmitter receptors in the central nervous system and aging: Pharmacological aspect (review)

1984 • 36 citations

Age-dependent increase in [3H]verapamil binding to rat cortical membranes

1985 • 35 citations

Functionality of the liver glucocorticoid receptor during the life cycle and development of a low-affinity membrane binding site

1978 • 32 citations

Chapter 30 The striatal dopaminergic system as a model for modulation of altered neurotransmitter action during aging: effects of dietary and neuroendocrine manipulations

1986 • 29 citations

Effect of Aging on the Dissociation Kinetics and Estradiol Receptor Nuclear Interactions in Mouse Uteri: Correlation with Biological Effects*

1986 • 27 citations

Age-Associated Changes in Nuclear Binding of Rat Uterine Estradiol Receptor Complexes

1985 • 25 citations

The influence of age on the calcium-efflux pathway and matrix calcium buffering power in brain mitochondria

1986 • 24 citations

Glucocorticoid receptors in WI-38 fibroblasts Characterization and changes with population doubling in culture

1979 • 24 citations

Glucocorticoid Receptors in Adult and Senescent Rat Liver*

1983 • 23 citations

Endocrine aging in CBA mice: Characterization of uterine cytosolic and nuclear sex steroid receptors

1982 • 21 citations

On the Presence of Nonfunctional Uterine Estrogen Receptors in Middle-Aged and Old C₅₇BL/6 J Mice*

1985 • 20 citations

Impaired Adrenergic Stimulation of Rat Parotid Cell Glucose Oxidation During Aging: The Role of Calcium

1986 • 20 citations

Alpha1-adrenergic stimulation of phosphatidylinositol-phosphatidic acid turnover in rat parotid cells.

1982 • 19 citations

Ionophore A23187 partially reverses LH secretory defect of pituitary cells from old rats

1987 • 19 citations

Hepatic Glucocorticoid Binders in Mature and Senescent C57BL/6J Male Mice

1976 • 19 citations

Changes in cortisol binding to soluble receptor proteins in rat liver and thymus during development and ageing

1975 • 17 citations

Effect of Maturation and Age on Lymphocyte Proliferation Induced by A23187 Through an Interleukin-Independent Pathway

1985 • 17 citations

Studies on the age-related decline in the response of lymphoid cells to mitogens: Measurements of Concanavalin A binding and stimulation of calcium and sugar uptake in thymocytes from rats of varying ages

1986 • 16 citations

Corticosterone binding in cytosols from brain regions of mature and senescent male C57BL/6J mice

1976 • 14 citations

Decreased estrogenic stimulation of RNA polymerase II in aged rat uteri is apparently due to reduced nuclear binding of receptor-estradiol complexes.

1985 • 14 citations

Age-Related Changes in the Formation of Glucocorticoid and Insulin Receptors during Lectin-Induced Activation of Human Peripheral Blood Lymphocytes

1985 • 8 citations

Public Policy and the Aging

1985 • 8 citations

Steroid-receptor complexes and their interaction with the rat liver nuclei during ontogenesis

1986 • 8 citations

Effect of age upon the uptake and binding of calcium in rat aorta

1984 • 8 citations

Impaired conversion of rat uterine estradiol receptors during aging

1986 • 7 citations

Effect of age on myofibrillar protease activity and muscle binding of glucocorticoid hormones in the rat

1981 • 7 citations

Stimulation of parotid cell glucose oxidation

1983 • 3 citations