Decreased muscarinic receptor binding in subjects with schizophrenia: a study of the human hippocampal formation

Diagnostic and Statistical Manual of Mental Disorders, 3rd ed

1981 • 7,500 citations

Implications of Normal Brain Development for the Pathogenesis of Schizophrenia

1987 • 3,683 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

Muscarinic Receptor Subtypes

1990 • 1,346 citations

Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats

1998 • 1,002 citations

Schizophrenia: A neural diathesis-stress model.

1997 • 847 citations

The Human Brain

1999 • 759 citations

Cholinergic innervation of the rat hippocampus as revealed by choline acetyltransferase immunocytochemistry: A combined light and electron microscopic study

1985 • 594 citations

The Human Brain: Surface, Three-Dimensional Sectional Anatomy and MRI

1991 • 586 citations

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

1987 • 442 citations

Expression of m1-m4 muscarinic acetylcholine receptor proteins in rat hippocampus and regulation by cholinergic innervation

1995 • 413 citations

Neurochemistry and pharmacology of the major hippocampal transmitter systems: Synaptic and nonsynaptic interactions

1998 • 362 citations

Cholinergic Hyperactivity and Negative Schizophrenic Symptoms

1989 • 353 citations

Psychopathology and the Brain

1992 • 325 citations

Cell biology of the hippocampal formation in schizophrenia

1999 • 324 citations

Tissue pH as an indicator of mRNA preservation in human post-mortem brain

1995 • 318 citations

Psychopathology and the Brain

1991 • 279 citations

Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells.

1992 • 271 citations

SCHIZOPHRENIA AND THE LIMBIC SYSTEM

1974 • 223 citations

Relational features of acetylcholine, noradrenaline, serotonin and GABA axon terminals in the stratum radiatum of adult rat hippocampus (CA1)

1995 • 198 citations

Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and α1-adrenergic receptors in vitro

1999 • 190 citations

Clozapine is a potent and selective muscarinic M4 receptor agonist

1994 • 179 citations

The inositol 1,4,5‐trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA.

1992 • 156 citations

Biochemistry of Dementia

1981 • 155 citations

Preclinical pharmacology of neuroleptics: focus on new generation compounds.

1996 • 135 citations

An Improved Approach to Prepare Human Brains for Research

1995 • 130 citations

Problem of diagnosis in postmortem brain studies of schizophrenia

1996 • 120 citations

Muscarinic cholinergic hyperactivity in schizophrenia

1991 • 116 citations

Glutamate in schizophrenia: clinical and research implications

1997 • 94 citations

Dopamine in Schizophrenia

1996 • 93 citations

Increased hippocampal acetylcholine release during a working memory task

1996 • 81 citations

Antischizophrenic drugs: Affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects

1974 • 75 citations

Biochemistry of Dementia

1980 • 71 citations

Differential alterations in muscarinic receptor subtypes in Alzheimer's disease: Implications for cholinergic-based therapies

1995 • 68 citations

Clozapine is a potent and selective muscarinic antagonist at the five cloned human muscarinic acetylcholine receptors expressed in CHO-K1 cells

1991 • 68 citations

The cholinergic system in Alzheimer's disease

1980 • 67 citations

Serotonin2 receptors and the serotonin transporter in the schizophrenic brain

1995 • 60 citations

The Effects of AMPA‐induced Lesions of the Medial Septum and Vertical Limb Nucleus of the Diagonal Band of Broca on Spatial Delayed Non‐matching to Sample and Spatial Learning in the Water Maze

1995 • 57 citations

Chapter 28 Physiological mechanisms of cholinergic action in the hippocampus

1990 • 56 citations

Demonstration of the facilitatory role of 8-OH-DPAT on cholinergic transmission in the rat hippocampus using in vivo microdialysis

1997 • 54 citations

Enhancement of cortical and hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by BAY×3702 in freely moving rats

1999 • 53 citations

Changes in the serotonin transporter in the hippocampus of subjects with schizophrenia identified using [3H]paroxetine

1996 • 47 citations

Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus

1993 • 29 citations

Does dopamine exert a tonic inhibitory control on the release of striatal acetylcholine in vivo?

1994 • 27 citations