Leukemia inhibitory factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line. Role of STAT pathway.

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation

1995 • 2,525 citations

Cytokine signal transduction

1994 • 1,358 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1994 • 1,015 citations

Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components

1994 • 972 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

Association of Transcription Factor APRF and Protein Kinase Jak1 with the Interleukin-6 Signal Transducer gp130

1994 • 822 citations

A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

1993 • 797 citations

Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein

1992 • 772 citations

Release of Multiple Hormones by a Direct Action of Interleukin-1 on Pituitary Cells

1987 • 670 citations

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.

1992 • 661 citations

LIFRβ and gp130 as Heterodimerizing Signal Transducers of the Tripartite CNTF Receptor

1993 • 632 citations

The Receptor for Ciliary Neurotrophic Factor

1991 • 604 citations

Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.

1991 • 587 citations

Cardiotrophin-1

1995 • 432 citations

The alphas, betas, and kinases of cytokine receptor complexes

1993 • 418 citations

A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)

1992 • 378 citations

INTERLEUKIN-6 STIMULATES ANTERIOR PITUITARY HORMONE RELEASEIN VITRO.

1989 • 323 citations

Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion.

1994 • 251 citations

Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor.

1994 • 213 citations

Paradoxical responses of hypothalamic corticotropin-releasing factor (CRF) messenger ribonucleic acid (mRNA) and CRF-41 peptide and adenohypophysial proopiomelanocortin mRNA during chronic inflammatory stress.

1992 • 198 citations

Activation of Acute Phase Response Factor (APRF)/Stat3 Transcription Factor by Growth Hormone

1995 • 180 citations

Intrinsic Pituitary Interleukin-1β Is Induced by Bacterial Lipopolysaccharide**

1990 • 142 citations

Human and murine pituitary expression of leukemia inhibitory factor. Novel intrapituitary regulation of adrenocorticotropin hormone synthesis and secretion.

1995 • 134 citations

Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion

1994 • 130 citations

Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: identification as leukemia inhibitory factor.

1992 • 122 citations

Interleukin-2 and interleukin-2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures.

1992 • 109 citations

In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.

1995 • 106 citations

The Protooncogene c-fosIs Induced by Corticotropin-Releasing Factor and Stimulates Proopiomelanocortin Gene Transcription in Pituitary Cells

1991 • 103 citations

Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1.

1995 • 92 citations

Effects of Protein Kinase-C-Related Adrenocorticotropin Secretagogues and Interleukin-1 on Proopiomelanocortin Gene Expression in Rat Anterior Pituitary Cells*

1989 • 89 citations

Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation.

1994 • 81 citations

The molecular biology of the CNTF receptor

1993 • 80 citations

Differential tyrosine phosphorylation of JAK1, JAK2, and STAT1 by growth hormone and interferon-gamma in IM-9 cells.

1994 • 75 citations

In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade.

1993 • 67 citations

The molecular biology of the CNTF receptor

1993 • 53 citations

INTERLEUKIN-6 SECRETING HUMAN PITUITARY ADENOMASIN VITRO

1991 • 52 citations

Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by cFos-dependent and -independent pathways: characterization of an AP1 site in exon 1

1995 • 48 citations

In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3

1995 • 47 citations

Defective Glucocorticoid Regulation of Proopiomelanocortin Gene Expression and Peptide Secretion in a Small Cell Lung Cancer Cell Line*

1990 • 44 citations

Proopiomelanocortin Gene Promoter Elements Required for Constitutive and Glucocorticoid-Repressed Transcription

1991 • 43 citations

Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein.

1994 • 42 citations

Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein

1994 • 15 citations

In Vitro Activation of the Transcription Factor Gamma Interferon Activation Factor by Gamma Interferon: Evidence for a Tyrosine Phosphatase/Kinase Signaling Cascade

1993 • 12 citations