Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

Toll-like receptor control of the adaptive immune responses

2004 • 4,092 citations

Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences

2004 • 3,040 citations

The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases

2002 • 2,592 citations

The immunological and genetic basis of inflammatory bowel disease

2003 • 1,766 citations

Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial

2003 • 1,139 citations

Immune Regulation by helminth parasites: cellular and molecular mechanisms

2003 • 1,102 citations

Probiotics in the management of atopic eczema

2000 • 995 citations

Human Metapneumovirus and Lower Respiratory Tract Disease in Otherwise Healthy Infants and Children

2004 • 927 citations

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

2003 • 811 citations

Lactobacillus species prevents colitis in interleukin 10 gene–deficient mice

1999 • 771 citations

Trichuris suis therapy in Crohn's disease

2004 • 740 citations

Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: epidemiological study

2000 • 697 citations

Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells

2002 • 632 citations

Asthma: an epidemic of dysregulated immunity

2002 • 613 citations

Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

2001 • 605 citations

Links between innate and adaptive immunity via type I interferon

2002 • 583 citations

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4+ T Cells

2001 • 538 citations

Tolerance and Autoimmunity

2001 • 453 citations

Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease

2003 • 413 citations

Anisakis simplex: dangerous — dead and alive?

2002 • 402 citations

Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?

2001 • 386 citations

Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma

2001 • 365 citations

Long‐Term Treatment of Intestinal Helminths Increases Mite Skin‐Test Reactivity in Gabonese Schoolchildren

2004 • 339 citations

Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes

2003 • 312 citations

A well‐tolerated grass pollen‐specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections

2001 • 283 citations

Heligmosomoides polygyrus inhibits established colitis in IL‐10‐deficient mice

2004 • 278 citations

Schistosomiasis Decreases Central Nervous System Inflammation and Alters the Progression of Experimental Autoimmune Encephalomyelitis

2003 • 260 citations

Immunomodulation of experimental autoimmune encephalomyelitis by helminth ova immunization

2002 • 248 citations

No effect of oral treatment with an intestinal bacterial strain, Lactobacillus rhamnosus (ATCC 53103), on birch‐pollen allergy: a placebo‐controlled double‐blind study

2002 • 243 citations

An Enteric Helminth Infection Protects Against an Allergic Response to Dietary Antigen

2002 • 238 citations

Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells

2004 • 213 citations

Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice.

1993 • 176 citations

Concurrent infection with Schistosoma mansoni attenuates inflammation induced changes in colonic morphology, cytokine levels, and smooth muscle contractility of trinitrobenzene sulphonic acid induced colitis in rats

2003 • 168 citations

Atypical Pathogen Infection in Adults with Acute Exacerbation of Bronchial Asthma

2003 • 164 citations

Exposure to Infant Siblings During Early Life and Risk of Multiple Sclerosis

2005 • 164 citations

Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: Involvement of phosphatidylinositol 3-kinase and nuclear factor ?B pathways in tumor necrosis factor ? production in rheumatoid arthritis

2002 • 163 citations

Respiratory Syncytial Virus Predisposes Mice to Augmented Allergic Airway Responses Via IL-13-Mediated Mechanisms

2001 • 152 citations

Helminth infection modulates the development of allergen-induced airway inflammation

2004 • 150 citations

Use of Bacille Calmette–Guèrin (BCG) in multiple sclerosis

1999 • 145 citations

Influenza Virus Lung Infection Protects from Respiratory Syncytial Virus–Induced Immunopathology

2000 • 138 citations

Mucosal co-application of lactic acid bacteria and allergen induces counter-regulatory immune responses in a murine model of birch pollen allergy

2003 • 128 citations

Atypical pathogens and respiratory tract infections

2004 • 124 citations

Effect of Bacillus Calmette-Guerin vaccination on new-onset type 1 diabetes. A randomized clinical study.

1999 • 121 citations

The effect of neonatal BCG vaccination on atopy and asthma at age 7 to 14 years: An historical cohort study in a community with a very low prevalence of tuberculosis infection and a high prevalence of atopic disease

2003 • 121 citations

Respiratory Syncytial Virus in Allergic Lung Inflammation Increases Muc5ac and Gob-5

2004 • 115 citations

Tapeworm Infection Reduces Epithelial Ion Transport Abnormalities in Murine Dextran Sulfate Sodium-Induced Colitis

2001 • 111 citations

Mycoplasma pneumoniae Induces Chronic Respiratory Infection, Airway Hyperreactivity, and Pulmonary Inflammation: a Murine Model of Infection-Associated Chronic Reactive Airway Disease

2002 • 106 citations

Triggering of Innate Immune Responses by Schistosome Egg Glycolipids and Their Carbohydrate Epitope GalNAcβ1‐4(Fucα1‐2Fucα1‐3)GlcNAc

2002 • 97 citations

Infection of mice with the helminth Strongyloides stercoralis suppresses pulmonary allergic responses to ovalbumin

2001 • 97 citations

Mini‐review: Regulatory T cells and infection: suppression revisited

2004 • 97 citations

The influence of infections on the development and severity of allergic disorders

2000 • 90 citations

Respiratory syncytial virus‐induced CCL5/RANTES contributes to exacerbation of allergic airway inflammation

2003 • 86 citations

Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells

2004 • 78 citations

The effects ofMycobacterium vaccaeon allergen-induced airway responses in atopic asthma

2003 • 75 citations

Influenza A Virus Infection Inhibits the Efficient Recruitment of Th2 Cells into the Airways and the Development of Airway Eosinophilia

2003 • 72 citations

Mycobacterium vaccae induces a population of pulmonary CD11c⁺ cells with regulatory potential in allergic mice

2004 • 69 citations

Infection withMycobacterium bovisBCG Diverts Traffic of Myelin Oligodendroglial Glycoprotein Autoantigen-Specific T Cells Away from the Central Nervous System and Ameliorates Experimental Autoimmune Encephalomyelitis

2003 • 60 citations

Lower prevalence of reported asthma in adolescents with symptoms of rhinitis that received neonatal BCG

2004 • 58 citations

Effect of Bacille Calmette-Guérin Vaccination on C-Peptide Secretion in Children Newly Diagnosed With IDDM

1998 • 58 citations

Changes in Pulmonary Function and Parasite Burden in Rats Infected with Strongyloides venezuelensis Concomitant with Induction of Allergic Airway Inflammation

2003 • 56 citations

Suppression of allergic airway disease using mycobacterial lipoglycans

2004 • 55 citations

Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages

2003 • 54 citations

Tissue Parasites in Patients with Chronic Urticaria

2003 • 51 citations

Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice

2004 • 48 citations

Environmental Modulation of Autoimmune Arthritis Involves the Spontaneous Microbial Induction of T Cell Responses to Regulatory Determinants Within Heat Shock Protein 65

2001 • 47 citations

Allergic airway inflammation is exacerbated during acute influenza infection and correlates with increased allergen presentation and recruitment of allergen‐specific T‐helper type 2 cells

2004 • 47 citations

Cross-reactivity of T lymphocytes in infection and autoimmunity

2004 • 46 citations

Modulation of Inhaled Antigen-Induced IgE Tolerance by Ongoing Th2 Responses in the Lung

2001 • 42 citations

Prior Bordetella pertussis infection modulates allergen priming and the severity of airway pathology in a murine model of allergic asthma

2004 • 42 citations

Effect of repeated intradermal injections of heat‐inactivated Mycobacterium bovis bacillus Calmette–Guérin in adult asthma

2004 • 38 citations

Dendritic cells from Chlamydia‐infected mice show altered Toll‐like receptor expression and play a crucial role in inhibition of allergic responses to ovalbumin

2004 • 34 citations

Infection with Influenza A Virus Leads to Flu Antigen-Induced Cutaneous Anaphylaxis in Mice

2002 • 28 citations

Lyme disease and current aspects of immunization.

2002 • 22 citations

Inhibition of allergic disorders by infection with bacteria or the exposure to bacterial products

2003 • 22 citations

Effects of primary and secondary low‐grade respiratory syncytial virus infections in a murine model of asthma

2004 • 21 citations