Epithelial autotoxicity of nitric oxide: role in the respiratory cytopathology of pertussis.

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

1989 • 1,747 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform.

1992 • 1,004 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1993 • 734 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

Aminoguanidine, a Novel Inhibitor of Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction

1992 • 609 citations

EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.

1990 • 512 citations

Superoxide sensitivity of the Escherichia coli aconitase.

1991 • 499 citations

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

1991 • 436 citations

Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.

1989 • 405 citations

Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide.

1992 • 283 citations

Multiple Cytokines Are Required to Induce Hepatocyte Nitric Oxide Production and Inhibit Total Protein Synthesis

1990 • 273 citations

The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids

1992 • 233 citations

Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells.

1991 • 192 citations

Ability of Monomeric Peptidoglycan Fragments from Neisseria gonorrhoeae to Damage Human Fallopian-Tube Mucosa

1984 • 180 citations

Detection, isolation, and analysis of a released Bordetella pertussis product toxic to cultured tracheal cells

1982 • 155 citations

Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases

1991 • 152 citations

Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes.

1992 • 150 citations

Biological activities and chemical composition of purified tracheal cytotoxin of Bordetella pertussis

1989 • 126 citations

The Pyrogenicity of the Synthetic Adjuvant Muramyl Dipeptide and Two Structural Analogues

1978 • 113 citations

Release of soluble peptidoglycan from growing conococci: demonstration of anhydro-muramyl-containing fragments

1980 • 106 citations

Primary structure of the peptidoglycan-derived tracheal cytotoxin of Bordetella pertussis

1989 • 101 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 94 citations

Interleukin-1 is linked to the respiratory epithelial cytopathology of pertussis

1993 • 76 citations

Induction of nitric oxide synthase activity by toxic shock syndrome toxin 1 in a macrophage-monocyte cell line.

1992 • 71 citations

Somnogenic activity of immune response modifiers

1990 • 67 citations

PERTUSSIS

1975 • 65 citations

Effects of Bordetella pertussis infection on human respiratory epithelium in vivo and in vitro

1991 • 64 citations

Dermonecrotic toxin and tracheal cytotoxin, putative virulence factors of Bordetella avium

1988 • 63 citations

Induction of interleukin 1 by synthetic and naturally occurring muramyl peptides.

1986 • 62 citations

Lipopolysaccharide and cytokines induce a macrophage-type of nitric oxide synthase in bovine retinal pigmented epithelial cells

1992 • 60 citations

Selective isolation and culture of a proliferating epithelial cell population from the hamster trachea

1980 • 55 citations

Induction, in vivo and in vitro, of macrophage membrane interleukin-1 by adjuvant-active synthetic muramyl peptides

1987 • 21 citations