Back to search

RECOMBINANT TNF-α MEDIATED REGULATION OF THE IκB-α/NF-κB SIGNALING PATHWAY: EVIDENCE FOR THE ENHANCEMENT OF PRO- AND ANTI-INFLAMMATORY CYTOKINES IN ALVEOLAR EPITHELIAL CELLS

Data up to Jan 2025

Published2002
Citations26
References32

Total Citations Per Year

Abstract

References (32)

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB: a key role in inflammatory diseases

2001 • 3,664 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

1997 • 1,802 citations

Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer

2001 • 1,548 citations

Series Introduction: The transcription factor NF-κB and human disease

2001 • 984 citations

Two tumour necrosis factor receptors: structure and function

1995 • 800 citations

Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human Monocytes

1995 • 698 citations

Multiple signals converging on NF-κB

1999 • 483 citations

Cytokines of the Lung

1990 • 443 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

NF-κB as a therapeutic target in chronic inflammation: recent advances

2000 • 377 citations

Inosine Inhibits Inflammatory Cytokine Production by a Posttranscriptional Mechanism and Protects Against Endotoxin-Induced Shock

2000 • 316 citations

Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1α and NF-κB Redox Sensitivity

2000 • 237 citations

In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.

1989 • 220 citations

Differential Regulation of Interleukin-10 (IL-10) and IL-12 by Glucocorticoids In Vitro

1998 • 203 citations

Interleukin-8 Mediates Injury from Smoke Inhalation to both the Lung Endothelial and the Alveolar Epithelial Barriers in Rabbits

1999 • 101 citations

O2-evoked regulation of HIF-1α and NF-κB in perinatal lung epithelium requires glutathione biosynthesis

2000 • 101 citations

Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium.

2001 • 83 citations

ALVEOLAR EPITHELIAL BARRIER

2000 • 79 citations

CHEMIOXYEXCITATION (Δp O2/ROS)-DEPENDENT RELEASE OF IL-1β, IL-6 AND TNF-α: EVIDENCE OF CYTOKINES AS OXYGEN-SENSITIVE MEDIATORS IN THE ALVEOLAR EPITHELIUM

2001 • 76 citations

α-Melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor κB translocation and activation: evidence for involvement of an interleukin-1β193‒195 receptor antagonism in the alveolar epithelium

2001 • 70 citations

Phosphodiesterase 4 inhibitors as novel anti-inflammatory agents

1999 • 66 citations

Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independent

1998 • 62 citations

Resistance of the Alveolar Epithelium to Injury from Septic Shock in Sheep

1995 • 56 citations

Effect of Adrenoreceptors on Endotoxin-induced Cytokines and Lipid Peroxidation in Lung Explants

1999 • 54 citations

The biphasic immunoregulation of pyrimidylpiperazine (Y‐40138) is IL‐10 sensitive and requires NF‐κB targeting in the alveolar epithelium

2001 • 27 citations

Oxidant injury to the alveolar epithelium: biochemical and pharmacologic studies.

1993 • 25 citations

A novel anti-rheumatic drug suppresses tumor necrosis factor-α and augments interleukin-10 in adjuvant arthritic rats

2000 • 23 citations

A novel dual regulator of tumor necrosis factor-α and interleukin-10 protects mice from endotoxin-induced shock

2000 • 20 citations

Targeting the alveolar epithelium in acute lung injury

1996 • 7 citations

Cited By (0)

No citing papers found in database

RECOMBINANT TNF-α MEDIATED REGULATION OF THE IκB-α/NF-κB SIGNALING PATHWAY: EVIDENCE FOR… (2002) – Cytokine | Metascience Observatory Explorer