RECOMBINANT TNF-α MEDIATED REGULATION OF THE IκB-α/NF-κB SIGNALING PATHWAY: EVIDENCE FOR THE ENHANCEMENT OF PRO- AND ANTI-INFLAMMATORY CYTOKINES IN ALVEOLAR EPITHELIAL CELLS
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References (32)
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 • 5,936 citations
NF-κB: a key role in inflammatory diseases
2001 • 3,664 citations
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
1986 • 2,771 citations
Structure, Regulation and Function of NF-kappaB
1994 • 2,110 citations
The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation
1997 • 1,802 citations
Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer
2001 • 1,548 citations
Series Introduction: The transcription factor NF-κB and human disease
2001 • 984 citations
Two tumour necrosis factor receptors: structure and function
1995 • 800 citations
Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human Monocytes
1995 • 698 citations
Multiple signals converging on NF-κB
1999 • 483 citations
Cytokines of the Lung
1990 • 443 citations
In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C
1989 • 389 citations
NF-κB as a therapeutic target in chronic inflammation: recent advances
2000 • 377 citations
Inosine Inhibits Inflammatory Cytokine Production by a Posttranscriptional Mechanism and Protects Against Endotoxin-Induced Shock
2000 • 316 citations
Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1α and NF-κB Redox Sensitivity
2000 • 237 citations
In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.
1989 • 220 citations
Differential Regulation of Interleukin-10 (IL-10) and IL-12 by Glucocorticoids In Vitro
1998 • 203 citations
Interleukin-8 Mediates Injury from Smoke Inhalation to both the Lung Endothelial and the Alveolar Epithelial Barriers in Rabbits
1999 • 101 citations
O2-evoked regulation of HIF-1α and NF-κB in perinatal lung epithelium requires glutathione biosynthesis
2000 • 101 citations
Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium.
2001 • 83 citations
ALVEOLAR EPITHELIAL BARRIER
2000 • 79 citations
CHEMIOXYEXCITATION (Δp O2/ROS)-DEPENDENT RELEASE OF IL-1β, IL-6 AND TNF-α: EVIDENCE OF CYTOKINES AS OXYGEN-SENSITIVE MEDIATORS IN THE ALVEOLAR EPITHELIUM
2001 • 76 citations
α-Melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor κB translocation and activation: evidence for involvement of an interleukin-1β193‒195 receptor antagonism in the alveolar epithelium
2001 • 70 citations
Phosphodiesterase 4 inhibitors as novel anti-inflammatory agents
1999 • 66 citations
Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independent
1998 • 62 citations
Resistance of the Alveolar Epithelium to Injury from Septic Shock in Sheep
1995 • 56 citations
Effect of Adrenoreceptors on Endotoxin-induced Cytokines and Lipid Peroxidation in Lung Explants
1999 • 54 citations
The biphasic immunoregulation of pyrimidylpiperazine (Y‐40138) is IL‐10 sensitive and requires NF‐κB targeting in the alveolar epithelium
2001 • 27 citations
Oxidant injury to the alveolar epithelium: biochemical and pharmacologic studies.
1993 • 25 citations
A novel anti-rheumatic drug suppresses tumor necrosis factor-α and augments interleukin-10 in adjuvant arthritic rats
2000 • 23 citations
A novel dual regulator of tumor necrosis factor-α and interleukin-10 protects mice from endotoxin-induced shock
2000 • 20 citations
Targeting the alveolar epithelium in acute lung injury
1996 • 7 citations
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