Purification of full-length recombinant human and rat type 1 11β-hydroxysteroid dehydrogenases with retained oxidoreductase activities

A Transgenic Model of Visceral Obesity and the Metabolic Syndrome

2001 • 1,743 citations

Does central obesity reflect “Cushing's disease of the omentum”?

1997 • 755 citations

11β-Hydroxysteroid Dehydrogenase

1997 • 725 citations

Intracrinology

1991 • 654 citations

Cloning and Expression of Rat cDNA Encoding Corticosteroid 11β-Dehydrogenase

1989 • 452 citations

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

1991 • 434 citations

Affinity Fusion Strategies for Detection, Purification, and Immobilization of Recombinant Proteins

1997 • 330 citations

Purification and Characterization of the Corticosteroid 1lβ-Dehydrogenase Component of the Rat Liver 1lβ-Hydroxysteroid Dehydrogenase Complex*

1988 • 308 citations

11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta- reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations.

1995 • 301 citations

The N-terminal Anchor Sequences of 11β-Hydroxysteroid Dehydrogenases Determine Their Orientation in the Endoplasmic Reticulum Membrane

1999 • 190 citations

11 beta-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity

1996 • 172 citations

Expression of 11β-Hydroxysteroid Dehydrogenase Using Recombinant Vaccinia Virus

1990 • 158 citations

Lumenal Orientation and Post-translational Modifications of the Liver Microsomal 11 -Hydroxysteroid Dehydrogenase

1995 • 117 citations

The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

1997 • 108 citations

In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I

2000 • 97 citations

Metabolic conversion as a pre‐receptor control mechanism for lipophilic hormones

2001 • 80 citations

11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta- reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations

1995 • 80 citations

The positive relationship between codon usage bias and translation initiation AUG context inSaccharomyces cerevisiae

1999 • 71 citations

Functional Expression, Characterization, and Purification of the Catalytic Domain of Human 11-β-Hydroxysteroid Dehydrogenase Type 1

2001 • 65 citations

The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

1997 • 64 citations

Selective inhibition of human type 1 11β‐hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics

1998 • 61 citations

The purification of 11β-hydroxysteroid dehydrogenase from mouse liver microsomes

1994 • 52 citations

Extraction of 11β-hydroxysteroid dehydrogenase from rat liver microsomes by detergents

1985 • 49 citations

Human 11β-Hydroxysteroid Dehydrogenase Type 1 Is Enzymatically Active in Its Nonglycosylated Form

2000 • 31 citations

Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli

2000 • 30 citations

Novel enzymological profiles of human 11β-hydroxysteroid dehydrogenase type 1

2001 • 26 citations

Use of Pichia pastoris as a Model Eukaryotic System

1998 • 22 citations

Heterogeneity of 11β-hydroxysteroid dehydrogenase type 1/microsomal carbonyl reductase (11β-HSD/CR) in guinea pig tissues. Purification of the liver form suggests modification in the cosubstrate binding site

2000 • 5 citations